MEAF6 and L3MBTL2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MEAF6	L3MBTL2
Gene Name		MYST/Esa1-associated factor 6	l(3)mbt-like 2 (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Centrosome NuA4 Histone Acetyltransferase Complex MOZ/MORF Histone Acetyltransferase Complex	Nucleus
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Methylated Histone Binding Histone Binding
	Biological Process	Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone H2A Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Histone H3-K14 Acetylation	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Chromatin Modification
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: BRPF1 CCDC85B FXR2 JADE1 L3MBTL2 LDOC1 MRGBP PLEKHF2 TRIM54	14 interactors: AES CBX3 HIST1H3A HIST1H4A MEAF6 MPP3 PAICS PHF10 PIAS1 RNF2 STAC3 STAM2 TBC1D9B TRIM42
Entrez ID		64769	83746
HPRD ID		13347	13954
Ensembl ID			ENSG00000100395
Uniprot IDs		Q9HAF1	Q969R5
PDB IDs			2W0T 3CEY 3F70
Enriched GO Terms of Interacting Partners?		Chromatin Modification Chromatin Organization Histone H3 Acetylation Chromosome Organization Transcription, DNA-templated Histone Acetylation Internal Peptidyl-lysine Acetylation RNA Biosynthetic Process Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Growth Negative Regulation Of Cell Growth RNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of Growth Histone H4-K12 Acetylation Peptidyl-lysine Modification Gene Expression Histone H4-K5 Acetylation Histone H4-K8 Acetylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Cell Growth Histone Modification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Microtubule Depolymerization Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Microtubule Polymerization Or Depolymerization Heterocycle Metabolic Process Regulation Of Cellular Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Histone H4 Acetylation	DNA Replication-dependent Nucleosome Assembly Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Methylation On Cytosine Chromatin Organization Cellular Nitrogen Compound Metabolic Process Chromatin Silencing At RDNA Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Nitrogen Compound Metabolic Process Protein-DNA Complex Assembly Gene Expression Chromosome Organization Chromatin Silencing Chromatin Modification Negative Regulation Of Cellular Metabolic Process DNA Methylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Gene Expression, Epigenetic Regulation Of RNA Metabolic Process RNA Biosynthetic Process DNA Modification Histone Modification Histone H2A-K119 Monoubiquitination Gene Silencing Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Histone H4-K20 Demethylation Regulation Of Cellular Process Nucleosome Assembly Positive Regulation Of Anoikis Chromatin Assembly Negative Regulation Of Megakaryocyte Differentiation Positive Regulation Of Smooth Muscle Cell Differentiation Nucleosome Organization Chromatin Assembly Or Disassembly 'de Novo' IMP Biosynthetic Process Histone H3-K14 Acetylation RNA Metabolic Process Cellular Macromolecular Complex Assembly Chromatin Remodeling DNA Packaging Negative Regulation Of Hematopoietic Progenitor Cell Differentiation
Tagcloud ?			700r analyse balancing compaction competent defective dub essentially facilitates flag h2aub1 hek293 integral k675 lethal occupancy occupied polycomb prc1 repressed repressive ring2 seq stably sumo2 sumoylation tagged tails ubiquitinating
Tagcloud (Difference) ?			700r analyse balancing compaction competent defective dub essentially facilitates flag h2aub1 hek293 integral k675 lethal occupancy occupied polycomb prc1 repressed repressive ring2 seq stably sumo2 sumoylation tagged tails ubiquitinating
Tagcloud (Intersection) ?