BEND5 and VPS25

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		BEND5	VPS25
Gene Name		BEN domain containing 5	vacuolar protein sorting 25 homolog (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus	ESCRT II Complex Nucleus Nucleoplasm Nucleolus Mitochondrion Cytosol Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function		Structural Molecule Activity Protein Binding Protein Homodimerization Activity
	Biological Process		Transcription, DNA-templated Regulation Of Transcription, DNA-templated Endosomal Transport Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Organization
Pathways			Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: APP BUD31 BZRAP1 CTNNBIP1 DDR1 EIF3D FAM161A GFI1B GORASP2 GRAP2 LCE1B PRKAB2 RTP5 UBE2I USP2 USP20 USP7 VPS25 ZGPAT ZNF417	10 interactors: APIP BEND5 CHMP6 CRLF3 REL RHOXF2 SNF8 SPRY2 TRIM27 VPS36
Entrez ID		79656	84313
HPRD ID		07756	14396
Ensembl ID			ENSG00000131475
Uniprot IDs		Q7L4P6	Q9BRG1
PDB IDs			2ZME 3CUQ 3HTU
Enriched GO Terms of Interacting Partners?		Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Protein Deubiquitination Protein Catabolic Process Regulation Of Receptor Activity Protein Modification By Small Protein Removal Regulation Of Protein Metabolic Process Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Cellular Macromolecule Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of SUMO Transferase Activity Regulation Of Metabolic Process Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Proteolysis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Smooth Muscle Cell-matrix Adhesion Regulation Of Vascular Permeability Involved In Acute Inflammatory Response Synaptic Growth At Neuromuscular Junction Formation Of Cytoplasmic Translation Initiation Complex Regulation Of ERBB Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Collateral Sprouting In Absence Of Injury Negative Regulation Of Gene Expression Cellular Protein Metabolic Process Negative Regulation Of DNA-templated Transcription, Initiation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Regulation Of Protein Catabolic Process Cellular Process Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Mitotic Cell Cycle Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity	Endosomal Transport Vacuolar Transport Regulation Of Gene Expression Establishment Of Localization In Cell Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Interleukin-2 Secretion L-methionine Biosynthetic Process From S-adenosylmethionine Cellular Localization Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cytokine Production Protein Transport Establishment Of Protein Localization Intracellular Transport Mitotic Cell Cycle Process Regulation Of Transcription, DNA-templated S-adenosylmethionine Cycle Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Calcium Ion Import Endosome Transport Via Multivesicular Body Sorting Pathway Mitotic Cell Cycle Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Late Endosome To Vacuole Transport Regulation Of Intracellular Signal Transduction Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Protein Kinase Activity Lung Growth Interferon-gamma Secretion L-methionine Biosynthetic Process From Methylthioadenosine Regulation Of Transcription From RNA Polymerase II Promoter Membrane Organization Negative Regulation Of Kinase Activity Regulation Of Neurotrophin TRK Receptor Signaling Pathway Protein Localization L-methionine Salvage Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Positive Regulation Of Interleukin-12 Biosynthetic Process Bud Elongation Involved In Lung Branching Negative Regulation Of Cell Death Negative Regulation Of Transferase Activity Cell Cycle Process Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Protein Phosphorylation Establishment Of Organelle Localization Methionine Biosynthetic Process Regulation Of Interleukin-12 Biosynthetic Process
Tagcloud ?		app apps aptamer deliver delivery endothelial entrapped evaporation flurbiprofen functionalized glycol importantly loaded micelles murine offer peg pla polyethylene polylactic quantified retention solvent spectroscopy therapeutically transferrin transferring unmodified w	bmp consequent contexts directs endosomal endosome enu escrt fgf fgfr gestation hyperactivation hypomorphic limbs machineries mutagenesis mysterious patterning polydactylous polydactyly preferential shh sort sorting specification survive unperturbed vacuolar vertebrate
Tagcloud (Difference) ?		app apps aptamer deliver delivery endothelial entrapped evaporation flurbiprofen functionalized glycol importantly loaded micelles murine offer peg pla polyethylene polylactic quantified retention solvent spectroscopy therapeutically transferrin transferring unmodified w	bmp consequent contexts directs endosomal endosome enu escrt fgf fgfr gestation hyperactivation hypomorphic limbs machineries mutagenesis mysterious patterning polydactylous polydactyly preferential shh sort sorting specification survive unperturbed vacuolar vertebrate
Tagcloud (Intersection) ?