BEND5 and CTNNBIP1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		BEND5	CTNNBIP1
Description		BEN domain containing 5	catenin beta interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus	Nucleus Nucleoplasm Cytoplasm Cytosol Beta-catenin Destruction Complex Protein-containing Complex Beta-catenin-ICAT Complex
	Molecular Function	DNA Binding Protein Binding	Transcription Coactivator Binding Protein Binding Beta-catenin Binding Armadillo Repeat Domain Binding Transcription Regulator Inhibitor Activity
	Biological Process	Negative Regulation Of DNA-templated Transcription	Negative Regulation Of Transcription By RNA Polymerase II Branching Involved In Ureteric Bud Morphogenesis Regulation Of Vascular Permeability Involved In Acute Inflammatory Response Negative Regulation Of Cell Population Proliferation Anterior/posterior Pattern Specification Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein-containing Complex Assembly Positive Regulation Of Monocyte Differentiation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Canonical Wnt Signaling Pathway Negative Regulation Of Transcription Initiation By RNA Polymerase II Negative Regulation Of Mesenchymal Cell Proliferation Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways			Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS			Platelet distribution width ( 32888494) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		31 interacting genes: APP BUD31 CFTR CTNNBIP1 DDR1 EIF3D ERBB3 FAM161A FXR1 GFI1B GORASP2 GRAP2 HOXA1 LCE1B LMO3 NTAQ1 PIMREG PRKAB2 PTGR2 RTP5 SMARCD1 TSC1 TSPOAP1 UBE2I USP2 USP20 USP7 VPS25 ZGPAT ZNF417 ZNF688	19 interacting genes: BEND5 CTNNA2 CTNNB1 EMD GINS4 INCA1 JUP KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP5-9 MSS51 NBPF19 NOTCH2NLA P4HA3 REL SPATA24 TCF7L2 USHBP1
Entrez ID		79656	56998
HPRD ID		07756	09677
Ensembl ID		ENSG00000162373	ENSG00000178585
Uniprot IDs		A0A0S2Z5N0 Q7L4P6	Q9NSA3
PDB IDs			1LUJ 1M1E 1T08
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Communication Regulation Of Signaling Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Long-term Synaptic Potentiation Cysteine-type Endopeptidase Activity Negative Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Signaling Receptor Activity	Catenin-TCF7L2 Complex Intermediate Filament Catenin Complex Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Beta-catenin-TCF7L2 Complex Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Proteoglycan Biosynthetic Process Cellular Response To Indole-3-methanol Protein-DNA Complex Response To Indole-3-methanol Nuclear Receptor Binding Alpha-catenin Binding Presynaptic Active Zone Cytoplasmic Component Beta-catenin-TCF Complex Regulation Of Canonical Wnt Signaling Pathway Regulation Of Fibroblast Proliferation Keratin Filament Postsynaptic Density, Intracellular Component Canonical Wnt Signaling Pathway Positive Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Glycoprotein Metabolic Process Cadherin Binding Pancreas Development Regulation Of Wnt Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Wnt Signaling Pathway Regulation Of Glycoprotein Biosynthetic Process Adherens Junction Detection Of Mechanical Stimulus Glial Cell Fate Determination Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation TMEM240-body Gamma-catenin-TCF7L2 Complex Intercalated Disc Transcription Corepressor Binding Skin Development Mesenchymal Stem Cell Differentiation Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Mitotic Cell Cycle, Embryonic Beta-catenin-ICAT Complex Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Renal Inner Medulla Development Scrib-APC-beta-catenin Complex Renal Outer Medulla Development Renal Vesicle Formation Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Branching Involved In Lung Morphogenesis Neural Plate Development Positive Regulation Of Nucleocytoplasmic Transport
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