SNRPF and SRSF5

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		SNRPF	SRSF5
Gene Name		small nuclear ribonucleoprotein polypeptide F	serine/arginine-rich splicing factor 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U7 SnRNP U1 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Nuclear Speck
	Molecular Function	RNA Binding Protein Binding	Nucleotide Binding Protein Binding Poly(A) RNA Binding RS Domain Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription Histone MRNA Metabolic Process RNA Splicing Gene Expression MRNA 3'-end Processing NcRNA Metabolic Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Splice Site Selection MRNA Processing MRNA Export From Nucleus RNA Splicing Response To Wounding Gene Expression MRNA 3'-end Processing Regulation Of Cell Cycle
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Metabolism of non-coding RNA mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs snRNP Assembly Processing of Capped Intronless Pre-mRNA SLBP independent Processing of Histone Pre-mRNAs RNA Polymerase II Transcription Termination	mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: CLNS1A COIL DDX20 GEMIN5 GEMIN6 HOMER3 IKZF1 IL7R LNX1 LSM5 LSM6 LSM7 PSMA3 PUF60 SMN2 SNRPA1 SNRPD2 SNRPE SNRPG SRRT SRSF5 WDR77	16 interactors: CALM1 CD101 DYRK1A HIPK3 MAPK14 MAPK6 OLFM2 PPARGC1A RPS6KA1 SMURF1 SNRPF SREK1 SRPK1 SRPK2 SRSF1 TNK2
Entrez ID		6636	6430
HPRD ID		04645	02948
Ensembl ID			ENSG00000100650
Uniprot IDs		P62306	Q13243 Q86U32
PDB IDs		1VU2 1VU3 2Y9A 2Y9B 2Y9C 2Y9D 3CW1 3PGW 3S6N 4F77
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Assembly Ribonucleoprotein Complex Biogenesis NcRNA Metabolic Process Gene Expression RNA Metabolic Process Spliceosomal Complex Assembly Cellular Macromolecular Complex Assembly Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Component Assembly Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Termination Of RNA Polymerase II Transcription Cellular Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay DNA-templated Transcription, Termination MRNA 3'-end Processing Lymph Node Development RNA 3'-end Processing Histone MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Cellular Macromolecule Catabolic Process Positive Regulation Of Neutrophil Differentiation Metabolic Process Interleukin-7-mediated Signaling Pathway Cellular Process Positive Regulation Of T Cell Differentiation Positive Regulation Of Lymphocyte Differentiation Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of T Cell Mediated Cytotoxicity Primary MiRNA Processing Regulation Of T Cell Differentiation Positive Regulation Of NK T Cell Differentiation Aromatic Compound Catabolic Process Positive Regulation Of Granulocyte Differentiation T Cell Differentiation Regulation Of Lymphocyte Differentiation B Cell Activation	RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of MRNA Processing Regulation Of RNA Splicing Protein Phosphorylation Phosphorylation MRNA Metabolic Process RNA Processing Innate Immune Response Regulation Of Cellular Protein Metabolic Process Phosphate-containing Compound Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Peptidyl-serine Phosphorylation Cellular Protein Modification Process Positive Regulation Of Viral Genome Replication Intracellular Signal Transduction Glucose Metabolic Process Immune Response Defense Response Posttranscriptional Regulation Of Gene Expression Ribonucleoprotein Complex Assembly Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Cellular Metabolic Process Termination Of RNA Polymerase II Transcription Hexose Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Peptidyl-threonine Phosphorylation MAPK Cascade Negative Regulation Of Viral Genome Replication MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Cellular Response To Growth Factor Stimulus Signal Transduction Monosaccharide Metabolic Process Regulation Of MRNA Stability Response To Growth Factor Toll-like Receptor 5 Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Regulation Of RNA Stability Toll-like Receptor 10 Signaling Pathway Cellular Protein Metabolic Process Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Nuclear Speck Organization P38MAPK Cascade
Tagcloud ?			a014418 antiapoptotic anxa7 ar bcl2 bmi1 deregulation downregulating downregulation escape factual glioblastoma glycogen gsk3 gsk3alpha gsk3beta hnrnp manzamine mcl1 posttreatment ptpb1 reflected splicing srsf1 tyr u373 u87 va xl
Tagcloud (Difference) ?			a014418 antiapoptotic anxa7 ar bcl2 bmi1 deregulation downregulating downregulation escape factual glioblastoma glycogen gsk3 gsk3alpha gsk3beta hnrnp manzamine mcl1 posttreatment ptpb1 reflected splicing srsf1 tyr u373 u87 va xl
Tagcloud (Intersection) ?