CACNA1C and VCP

  • Number of citations of the paper that reports this interaction (PubMedID 21653829)
  • 54
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)

CACNA1C

VCP

Description calcium voltage-gated channel subunit alpha1 C valosin containing protein
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acoustic startle blink response ( 25387708)
  • Adult body size ( 32376654)
  • Adventurousness ( 30643258)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Aortic root size ( 28394258)
  • Appendicular lean mass ( 33097823)
  • Atypical femoral fracture in phosphonate treatment ( 31006051)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Bipolar disorder ( 18711365 34002096 33263727 31043756 28072414 20351715)
  • Bipolar disorder or major depressive disorder ( 20351715)
  • Bipolar I disorder ( 31043756)
  • Broad depression or bipolar disorder ( 30626913)
  • Broad depression or schizophrenia ( 30626913)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Diastolic blood pressure ( 30224653)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244)
  • Fractional exhaled nitric oxide (childhood) ( 24315451)
  • General risk tolerance (MTAG) ( 30643258)
  • Heel bone mineral density ( 28869591 30598549)
  • Hematocrit ( 32888494 27863252)
  • Hemoglobin ( 32888494)
  • Hemoglobin concentration ( 27863252)
  • Lumbar spine bone mineral density (integral) ( 27476799)
  • Lumbar spine bone mineral density (trabecular) ( 27476799)
  • Major depressive disorder and major depressive episode treated with electroconvulsive therapy ( 33483693)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Perceived intensity of aspartame ( 31005972)
  • Platelet count ( 32888494)
  • Platelet distribution width ( 32888494)
  • Plateletcrit ( 32888494)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale) ( 28525603)
  • Psychosis proneness (hypomanic personality scale) ( 28525603)
  • Red blood cell count ( 27863252 32888494 29403010)
  • Red blood cell traits ( 23222517)
  • Response to olanzapine in schizophrenia ( 29503163)
  • Resting heart rate ( 27798624 29769521)
  • Schizophrenia ( 23974872 25056061 28991256 29483656 21926974 22688191 30285260)
  • Schizophrenia or bipolar disorder ( 24280982)
  • Sensorimotor dexterity ( 31596458)
  • Short-term memory (digit-span task) ( 30741946)
  • Sleep quality ( 23728906)
  • Warfarin maintenance dose ( 18535201)
  • Response to quetiapine in schizophrenia ( 29503163)
Interacting Genes 25 interacting genes: ACTN2 ANKRD35 BSG C18orf32 CABP1 CACNB3 COPS5 DNAJA3 EFEMP1 FHL2 GNB1 HDAC4 IFT88 NUP133 PCBD1 PICK1 PPM1A PRKACA RIC3 RIMS1 RYR2 SRI SRRT TNIP2 VCP 98 interacting genes: ABHD17C AMFR ANKRD13A AR ASPSCR1 ATG5 ATXN1 ATXN3 ATXN7 BAG5 BRCA1 BRSK2 BUD23 CACNA1C CEP19 CLUAP1 CRMP1 CSTF1 DERL1 DGCR6 DTNB ELAVL1 EPHB4 EPSTI1 ESR1 GZMK HDAC6 HTT INSIG1 INSIG2 JAK2 LINC01554 LNX1 LZIC MAPK8IP2 MDM2 METTL17 NDRG1 NF1 NFKBIA NGLY1 NOD2 NSFL1C NTAQ1 NUB1 OPTN PBK PIK3R3 PLAA PPP1CC PPP1R11 PPP1R3A PPP1R7 PRKCD PSMA1 PSMC1 PTPN3 RIPK4 RNF10 RNF115 RNF19A RNF8 RPS6KA1 SELENOS SH2D2A SLC43A3 SNCA SPRTN STUB1 STX5 SUMO4 SVIP TMUB1 TOM1L1 TOMM34 TRIM54 UBASH3A UBC UBE4A UBE4B UBOX5 UBXN10 UBXN11 UBXN2B UBXN4 UBXN6 UFD1 USP7 VAMP2 VANGL2 VCF1 VCPIP1 VCPKMT WAC WRN XAF1 YWHAZ ZBTB25
Entrez ID 775 7415
HPRD ID 00246 03013
Ensembl ID ENSG00000151067 ENSG00000165280
Uniprot IDs A0A0A0MR67 A0A0A0MSA1 A0A804HI37 A0A804HIJ8 A0A804HJB6 A0A804HKC4 E9PDI6 F5H522 Q13936 Q59GU3 Q5V9X9 C9JUP7 P55072
PDB IDs 1T0J 2BE6 2F3Y 2F3Z 2LQC 3G43 3OXQ 5V2P 5V2Q 6C0A 6DAD 6DAE 6DAF 6U39 6U3A 6U3B 6U3D 7L8V 8EOG 8EOI 8FD7 8FHS 8HLP 8HMA 8HMB 8UKO 8UKP 8WE6 8WE7 8WE8 8WE9 8WEA 3EBB 3HU1 3HU2 3HU3 3QC8 3QQ7 3QQ8 3QWZ 3TIW 4KDI 4KDL 4KLN 4KO8 4KOD 4P0A 5B6C 5C18 5C19 5C1A 5C1B 5DYG 5DYI 5EPP 5FTJ 5FTK 5FTL 5FTM 5FTN 5GLF 5IFS 5IFW 5KIW 5KIY 5X4L 6G2V 6G2W 6G2X 6G2Y 6G2Z 6G30 6HD0 6MCK 7BP8 7BP9 7BPA 7BPB 7JY5 7K56 7K57 7K59 7L5W 7L5X 7LMY 7LMZ 7LN0 7LN1 7LN2 7LN3 7LN4 7LN5 7LN6 7MDM 7MDO 7MHS 7OAT 7PUX 7R7S 7R7T 7R7U 7RL6 7RL7 7RL9 7RLA 7RLB 7RLC 7RLD 7RLF 7RLG 7RLH 7RLI 7RLJ 7VCS 7VCT 7VCU 7VCV 7VCX 7Y4W 7Y53 7Y59 8B5R 8FCL 8FCM 8FCN 8FCO 8FCP 8FCQ 8FCR 8FCT 8HL7 8HRZ 8KG2 8OOI 8PQX 8R0E 8RS9 8RSB 8RSC 8UV2 8UVO 8UVP 8UVQ 8VKU 8VLS 8VOV 8YKA 9BOQ
Enriched GO Terms of Interacting Partners?
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