CA8 and GGA2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CA8	GGA2
Gene Name		carbonic anhydrase VIII	golgi-associated, gamma adaptin ear containing, ARF binding protein 2
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm	Golgi Apparatus Trans-Golgi Network Endosome Membrane Clathrin Adaptor Complex Clathrin-coated Vesicle
	Molecular Function	Carbonate Dehydratase Activity Zinc Ion Binding	Protein Binding ADP-ribosylation Factor Binding
	Biological Process	One-carbon Metabolic Process Phosphatidylinositol-mediated Signaling	Intracellular Protein Transport Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951) Obesity-related traits ( 23251661) Response to amphetamines ( 22952603)
Protein-Protein Interactions		9 interactors: CRX GGA2 HSD17B14 ITPR1 LNX1 LRCH4 MAGED1 SPDL1 TBX3	30 interactors: AFTPH APP ARF1 ARF3 ATXN1 BACE1 BACE2 CA8 CCDC91 CLINT1 CLTC GGA1 GGA3 HGS HTT IGF2R LRP3 M6PR PIN1 RAB5A RABEP1 RABGEF1 RNF11 SORL1 SORT1 SPG21 STAB1 SYNRG TRIM23 VPS18
Entrez ID		767	23062
HPRD ID		00266	09347
Ensembl ID			ENSG00000103365
Uniprot IDs		P35219	Q9UJY4
PDB IDs		2W2J	1MHQ
Enriched GO Terms of Interacting Partners?		Atrioventricular Bundle Cell Differentiation Follicle-stimulating Hormone Secretion Positive Regulation Of Photoreceptor Cell Differentiation	Vesicle-mediated Transport Endocytosis Intracellular Transport Protein Transport Establishment Of Protein Localization Transport Establishment Of Localization In Cell Protein Localization Cellular Localization Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Lysosomal Transport Golgi Vesicle Transport Vacuolar Transport Cellular Protein Localization Endosomal Transport Regulation Of Vesicle-mediated Transport Endosome To Lysosome Transport Cytoplasmic Transport Visual Learning Membrane Organization Visual Behavior Protein Targeting To Lysosome Protein Localization To Lysosome Associative Learning Cellular Copper Ion Homeostasis Membrane Protein Ectodomain Proteolysis Signaling Protein Targeting To Vacuole Copper Ion Homeostasis Cell Communication Negative Regulation Of Signaling Establishment Of Protein Localization To Vacuole Learning Transition Metal Ion Homeostasis Membrane Protein Proteolysis Regulation Of Exocytosis Retrograde Vesicle-mediated Transport, Golgi To ER Regulation Of Synaptic Plasticity Regulation Of Protein Catabolic Process Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Phosphorylation Neural Plate Formation Negative Regulation Of Kit Signaling Pathway Positive Regulation Of Early Endosome To Recycling Endosome Transport Negative Regulation Of Tau-protein Kinase Activity Negative Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Negative Regulation Of Neurofibrillary Tangle Assembly Positive Regulation Of Choline O-acetyltransferase Activity
Tagcloud ?		a8344g anhydrase ataxia autophagic carbonic cerebellar cybrids distinctive encephalomyopathy exhibiting fibres gait harbouring inherited lc3 lifelong maternally merrf mtdna muscular myoclonus phospho ragged retardation staurosporine sts viii waddles wdl	addressed adulthood allele attributable byg c57bl c57bl6 disrupted ear establishes gga1 gga3 ggas harbors homozygous hypomorphic insertional knockout lethality mutagenesis neonatal ola129sv placement redundancy ribosylation runted survive tigm true
Tagcloud (Difference) ?		a8344g anhydrase ataxia autophagic carbonic cerebellar cybrids distinctive encephalomyopathy exhibiting fibres gait harbouring inherited lc3 lifelong maternally merrf mtdna muscular myoclonus phospho ragged retardation staurosporine sts viii waddles wdl	addressed adulthood allele attributable byg c57bl c57bl6 disrupted ear establishes gga1 gga3 ggas harbors homozygous hypomorphic insertional knockout lethality mutagenesis neonatal ola129sv placement redundancy ribosylation runted survive tigm true
Tagcloud (Intersection) ?