GGA2 and CCDC91

Number of citations of the paper that reports this interaction (PMID 12808037)
20

Data Source:
HPRD (in vitro, in vivo)

		GGA2	CCDC91
Gene Name		golgi-associated, gamma adaptin ear containing, ARF binding protein 2	coiled-coil domain containing 91
Image
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Trans-Golgi Network Endosome Membrane Clathrin Adaptor Complex Clathrin-coated Vesicle	Nucleoplasm Golgi Apparatus Membrane
	Molecular Function	Protein Binding ADP-ribosylation Factor Binding	Identical Protein Binding
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport	Protein Transport
Pathways
Drugs
Diseases
GWAS			Height ( 20881960 23563607) Obesity-related traits ( 23251661)
Protein-Protein Interactions		30 interactors: AFTPH APP ARF1 ARF3 ATXN1 BACE1 BACE2 CA8 CCDC91 CLINT1 CLTC GGA1 GGA3 HGS HTT IGF2R LRP3 M6PR PIN1 RAB5A RABEP1 RABGEF1 RNF11 SORL1 SORT1 SPG21 STAB1 SYNRG TRIM23 VPS18	6 interactors: ECT2 EWSR1 GGA1 GGA2 SYNRG TESC
Entrez ID		23062	55297
HPRD ID		09347	16905
Ensembl ID		ENSG00000103365	ENSG00000123106
Uniprot IDs		Q9UJY4	Q05D28 Q7Z6B0
PDB IDs		1MHQ	1OM9
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Endocytosis Intracellular Transport Protein Transport Establishment Of Protein Localization Transport Establishment Of Localization In Cell Protein Localization Cellular Localization Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Lysosomal Transport Golgi Vesicle Transport Vacuolar Transport Cellular Protein Localization Endosomal Transport Regulation Of Vesicle-mediated Transport Endosome To Lysosome Transport Cytoplasmic Transport Visual Learning Membrane Organization Visual Behavior Protein Targeting To Lysosome Protein Localization To Lysosome Associative Learning Cellular Copper Ion Homeostasis Membrane Protein Ectodomain Proteolysis Signaling Protein Targeting To Vacuole Copper Ion Homeostasis Cell Communication Negative Regulation Of Signaling Establishment Of Protein Localization To Vacuole Learning Transition Metal Ion Homeostasis Membrane Protein Proteolysis Regulation Of Exocytosis Retrograde Vesicle-mediated Transport, Golgi To ER Regulation Of Synaptic Plasticity Regulation Of Protein Catabolic Process Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Phosphorylation Neural Plate Formation Negative Regulation Of Kit Signaling Pathway Positive Regulation Of Early Endosome To Recycling Endosome Transport Negative Regulation Of Tau-protein Kinase Activity Negative Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Negative Regulation Of Neurofibrillary Tangle Assembly Positive Regulation Of Choline O-acetyltransferase Activity	Protein Transport Establishment Of Protein Localization Protein Localization Intracellular Protein Transport Cellular Protein Localization Intracellular Transport Establishment Of Localization In Cell Positive Regulation Of Sodium:proton Antiporter Activity Cellular Localization Regulation Of Sodium:proton Antiporter Activity Transport Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Megakaryocyte Differentiation Regulation Of Proton Transport Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Activation Of Rac GTPase Activity Vesicle-mediated Transport Positive Regulation Of Sodium Ion Transmembrane Transport
Tagcloud ?		addressed adulthood allele attributable byg c57bl c57bl6 disrupted ear establishes gga1 gga3 ggas harbors homozygous hypomorphic insertional knockout lethality mutagenesis neonatal ola129sv placement redundancy ribosylation runted survive tigm true
Tagcloud (Difference) ?		addressed adulthood allele attributable byg c57bl c57bl6 disrupted ear establishes gga1 gga3 ggas harbors homozygous hypomorphic insertional knockout lethality mutagenesis neonatal ola129sv placement redundancy ribosylation runted survive tigm true
Tagcloud (Intersection) ?