CA8 and CRX

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CA8	CRX
Gene Name		carbonic anhydrase VIII	cone-rod homeobox
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nucleus Transcription Factor Complex
	Molecular Function	Carbonate Dehydratase Activity Zinc Ion Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Nuclear Hormone Receptor Binding Leucine Zipper Domain Binding
	Biological Process	One-carbon Metabolic Process Phosphatidylinositol-mediated Signaling	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Visual Perception Circadian Rhythm Organ Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Photoreceptor Cell Differentiation Response To Stimulus Retina Development In Camera-type Eye
Pathways
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951) Obesity-related traits ( 23251661) Response to amphetamines ( 22952603)
Protein-Protein Interactions		9 interactors: CRX GGA2 HSD17B14 ITPR1 LNX1 LRCH4 MAGED1 SPDL1 TBX3	44 interactors: ABI2 AES ATG12 ATXN7 BANF1 C1orf109 C9orf72 CA8 CCNC CREBBP CSNK1G2-AS1 EIF5A EP300 GCM2 GUCD1 IPO13 KAT2A KIAA0141 KLHL32 LARP4 LONRF1 M1AP MDFI MLLT6 NIP7 NPAS2 NR2E3 NRL OSGIN1 PARK2 PDC PID1 PPP1R16B PRKAB2 PSMB10 QRICH1 RAX2 RBFOX1 ROR2 SFI1 SOX5 STK16 SZT2 UBXN2B
Entrez ID		767	1406
HPRD ID		00266	03748
Ensembl ID			ENSG00000105392
Uniprot IDs		P35219	O43186
PDB IDs		2W2J
Enriched GO Terms of Interacting Partners?		Atrioventricular Bundle Cell Differentiation Follicle-stimulating Hormone Secretion Positive Regulation Of Photoreceptor Cell Differentiation	Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Positive Regulation Of Rhodopsin Gene Expression N-terminal Peptidyl-lysine Acetylation Regulation Of Rhodopsin Gene Expression Transcription, DNA-templated Visual Perception Sensory Perception Of Light Stimulus Positive Regulation Of Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Mitochondrial Fusion Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cellular Process Organelle Organization Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Autophagy N-terminal Protein Amino Acid Acetylation Nuclear Envelope Reassembly Cellular Response To Stimulus Response To Stimulus Negative Regulation Of Wnt Signaling Pathway Cellular Metabolic Process Somitogenesis Cellular Nitrogen Compound Metabolic Process Developmental Process Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase II Promoter Histone Deubiquitination Neurological System Process Somite Development Cellular Response To Stress Regulation Of Type I Interferon Production Peptidyl-amino Acid Modification Peptidyl-lysine Modification Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Tagcloud ?		a8344g anhydrase ataxia autophagic carbonic cerebellar cybrids distinctive encephalomyopathy exhibiting fibres gait harbouring inherited lc3 lifelong maternally merrf mtdna muscular myoclonus phospho ragged retardation staurosporine sts viii waddles wdl	5sa aspect cofactor embryos exit hippo lats1 morphogenesis mst1 mst2 neurogenesis orchestrate otx5 phosphorylate photoreceptor pigmentation playing progenitor prolongs remarkably repressing retinal retinogenesis rhodopsin rx1 tead ww yap zebrafish
Tagcloud (Difference) ?		a8344g anhydrase ataxia autophagic carbonic cerebellar cybrids distinctive encephalomyopathy exhibiting fibres gait harbouring inherited lc3 lifelong maternally merrf mtdna muscular myoclonus phospho ragged retardation staurosporine sts viii waddles wdl	5sa aspect cofactor embryos exit hippo lats1 morphogenesis mst1 mst2 neurogenesis orchestrate otx5 phosphorylate photoreceptor pigmentation playing progenitor prolongs remarkably repressing retinal retinogenesis rhodopsin rx1 tead ww yap zebrafish
Tagcloud (Intersection) ?