CA8 and TBX3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CA8	TBX3
Gene Name		carbonic anhydrase VIII	T-box 3
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nucleus
	Molecular Function	Carbonate Dehydratase Activity Zinc Ion Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription RNA Polymerase II Transcription Factor Binding RNA Polymerase II Activating Transcription Factor Binding Protein Binding Sequence-specific DNA Binding
	Biological Process	One-carbon Metabolic Process Phosphatidylinositol-mediated Signaling	Negative Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Development Blood Vessel Development In Utero Embryonic Development Heart Looping Outflow Tract Morphogenesis Atrioventricular Bundle Cell Differentiation Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Cell Aging Positive Regulation Of Cell Proliferation Anterior/posterior Axis Specification, Embryo Organ Morphogenesis Specification Of Organ Position Stem Cell Maintenance Limbic System Development Male Genitalia Development Female Genitalia Development Negative Regulation Of Epithelial Cell Differentiation Mammary Gland Development Luteinizing Hormone Secretion Embryonic Forelimb Morphogenesis Forelimb Morphogenesis Embryonic Digit Morphogenesis Negative Regulation Of Apoptotic Process Negative Regulation Of Myoblast Differentiation Positive Regulation Of Cell Cycle Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Follicle-stimulating Hormone Secretion Mesoderm Morphogenesis Palate Development Ventricular Septum Morphogenesis Branching Involved In Mammary Gland Duct Morphogenesis Mammary Placode Formation Cardiac Muscle Cell Fate Commitment Sinoatrial Node Cell Development Cellular Senescence Positive Regulation Of Stem Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951) Obesity-related traits ( 23251661) Response to amphetamines ( 22952603)	Blood pressure ( 21572416 21909110) Colorectal cancer ( 23266556) Diastolic blood pressure ( 19430479) Mammographic density ( 22532574) PR interval ( 20062060) Prostate-specific antigen levels ( 21160077) Ventricular conduction ( 21076409)
Protein-Protein Interactions		9 interactors: CRX GGA2 HSD17B14 ITPR1 LNX1 LRCH4 MAGED1 SPDL1 TBX3	3 interactors: AES CA8 TOLLIP
Entrez ID		767	6926
HPRD ID		00266	03373
Ensembl ID			ENSG00000135111
Uniprot IDs		P35219	O15119
PDB IDs		2W2J	1H6F
Enriched GO Terms of Interacting Partners?		Atrioventricular Bundle Cell Differentiation Follicle-stimulating Hormone Secretion Positive Regulation Of Photoreceptor Cell Differentiation
Tagcloud ?		a8344g anhydrase ataxia autophagic carbonic cerebellar cybrids distinctive encephalomyopathy exhibiting fibres gait harbouring inherited lc3 lifelong maternally merrf mtdna muscular myoclonus phospho ragged retardation staurosporine sts viii waddles wdl	already alveolar cadherin comprising develops embryo functionally germ give gland highlighting hormone identity immunofluorescence knock lineage luminal mammary milk notably primed reconstitution repressed repressor sensing specification strict ulnar virgin
Tagcloud (Difference) ?		a8344g anhydrase ataxia autophagic carbonic cerebellar cybrids distinctive encephalomyopathy exhibiting fibres gait harbouring inherited lc3 lifelong maternally merrf mtdna muscular myoclonus phospho ragged retardation staurosporine sts viii waddles wdl	already alveolar cadherin comprising develops embryo functionally germ give gland highlighting hormone identity immunofluorescence knock lineage luminal mammary milk notably primed reconstitution repressed repressor sensing specification strict ulnar virgin
Tagcloud (Intersection) ?