GGA2 and SORL1

  • Number of citations of the paper that reports this interaction (PMID 11821067)
  • 25
  • Data Source:
  • HPRD (two hybrid, in vitro, in vivo)

GGA2

SORL1

Gene Name golgi-associated, gamma adaptin ear containing, ARF binding protein 2 sortilin-related receptor, L(DLR class) A repeats containing
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 23565137)
  • Cardiovascular disease risk factors ( 20838585)
Protein-Protein Interactions 30 interactors: AFTPH APP ARF1 ARF3 ATXN1 BACE1 BACE2 CA8 CCDC91 CLINT1 CLTC GGA1 GGA3 HGS HTT IGF2R LRP3 M6PR PIN1 RAB5A RABEP1 RABGEF1 RNF11 SORL1 SORT1 SPG21 STAB1 SYNRG TRIM23 VPS18 5 interactors: FURIN GGA1 GGA2 LRPAP1 PPP1CA
Entrez ID 23062 6653
HPRD ID 09347 03595
Ensembl ID ENSG00000103365 ENSG00000137642
Uniprot IDs Q9UJY4 E9PP43 Q92673
PDB IDs 1MHQ 2DM4 3G2S 3G2T
Enriched GO Terms of Interacting Partners?
Tagcloud ?
addressed  adulthood  allele  attributable  byg  c57bl  c57bl6  disrupted  ear  establishes  gga1  gga3  ggas  harbors  homozygous  hypomorphic  insertional  knockout  lethality  mutagenesis  neonatal  ola129sv  placement  redundancy  ribosylation  runted  survive  tigm  true 
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  psen2  snps  sporadic  triggers  turn  unlikely 
Tagcloud (Difference) ?
addressed  adulthood  allele  attributable  byg  c57bl  c57bl6  disrupted  ear  establishes  gga1  gga3  ggas  harbors  homozygous  hypomorphic  insertional  knockout  lethality  mutagenesis  neonatal  ola129sv  placement  redundancy  ribosylation  runted  survive  tigm  true 
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  psen2  snps  sporadic  triggers  turn  unlikely 
Tagcloud (Intersection) ?