GGA2 and ARF3

Number of citations of the paper that reports this interaction (PMID 10749927)
72

Data Source:
HPRD (two hybrid)

		GGA2	ARF3
Gene Name		golgi-associated, gamma adaptin ear containing, ARF binding protein 2	ADP-ribosylation factor 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Trans-Golgi Network Endosome Membrane Clathrin Adaptor Complex Clathrin-coated Vesicle	Golgi Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Binding ADP-ribosylation Factor Binding	GTPase Activity GTP Binding
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Small GTPase Mediated Signal Transduction Protein Transport Vesicle-mediated Transport Small Molecule Metabolic Process
Pathways			Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		30 interactors: AFTPH APP ARF1 ARF3 ATXN1 BACE1 BACE2 CA8 CCDC91 CLINT1 CLTC GGA1 GGA3 HGS HTT IGF2R LRP3 M6PR PIN1 RAB5A RABEP1 RABGEF1 RNF11 SORL1 SORT1 SPG21 STAB1 SYNRG TRIM23 VPS18	9 interactors: ARFIP1 ARFIP2 ATN1 GGA1 GGA2 GGA3 KIF23 PICK1 SLC2A4
Entrez ID		23062	377
HPRD ID		09347	00056
Ensembl ID		ENSG00000103365	ENSG00000134287
Uniprot IDs		Q9UJY4	B7ZB63 P61204
PDB IDs		1MHQ
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Endocytosis Intracellular Transport Protein Transport Establishment Of Protein Localization Transport Establishment Of Localization In Cell Protein Localization Cellular Localization Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Lysosomal Transport Golgi Vesicle Transport Vacuolar Transport Cellular Protein Localization Endosomal Transport Regulation Of Vesicle-mediated Transport Endosome To Lysosome Transport Cytoplasmic Transport Visual Learning Membrane Organization Visual Behavior Protein Targeting To Lysosome Protein Localization To Lysosome Associative Learning Cellular Copper Ion Homeostasis Membrane Protein Ectodomain Proteolysis Signaling Protein Targeting To Vacuole Copper Ion Homeostasis Cell Communication Negative Regulation Of Signaling Establishment Of Protein Localization To Vacuole Learning Transition Metal Ion Homeostasis Membrane Protein Proteolysis Regulation Of Exocytosis Retrograde Vesicle-mediated Transport, Golgi To ER Regulation Of Synaptic Plasticity Regulation Of Protein Catabolic Process Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Phosphorylation Neural Plate Formation Negative Regulation Of Kit Signaling Pathway Positive Regulation Of Early Endosome To Recycling Endosome Transport Negative Regulation Of Tau-protein Kinase Activity Negative Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Negative Regulation Of Neurofibrillary Tangle Assembly Positive Regulation Of Choline O-acetyltransferase Activity	Intracellular Protein Transport Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Establishment Of Localization In Cell Amylopectin Biosynthetic Process Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Cellular Localization Vesicle-mediated Transport Mitotic Spindle Midzone Assembly Positive Regulation Of Protein Catabolic Process Mitotic Spindle Elongation DNA Methylation Involved In Embryo Development Glucose Import Dendritic Spine Maintenance Transport Spindle Midzone Assembly Neuronal Ion Channel Clustering Maintenance Of Cell Polarity Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Toxin Metabolic Process Negative Regulation Of Actin Nucleation Long Term Synaptic Depression
Tagcloud ?		addressed adulthood allele attributable byg c57bl c57bl6 disrupted ear establishes gga1 gga3 ggas harbors homozygous hypomorphic insertional knockout lethality mutagenesis neonatal ola129sv placement redundancy ribosylation runted survive tigm true	abaxialized apex apices arf3a arfs biogenesis divergence factor3 hit lbl1 leafbladeless1 maize medicago misexpression pare perturbing phased recapitulate seedling sirnas spatiotemporal ta tas tas3 tasir transposons underlies vegetative
Tagcloud (Difference) ?		addressed adulthood allele attributable byg c57bl c57bl6 disrupted ear establishes gga1 gga3 ggas harbors homozygous hypomorphic insertional knockout lethality mutagenesis neonatal ola129sv placement redundancy ribosylation runted survive tigm true	abaxialized apex apices arf3a arfs biogenesis divergence factor3 hit lbl1 leafbladeless1 maize medicago misexpression pare perturbing phased recapitulate seedling sirnas spatiotemporal ta tas tas3 tasir transposons underlies vegetative
Tagcloud (Intersection) ?