CA8 and LRCH4

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		CA8	LRCH4
Name		carbonic anhydrase 8	leucine rich repeats and calponin homology domain containing 4
Structure			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Plasma Membrane Membrane PML Body
	Molecular Function	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Positive Regulation Of Calcium-mediated Signaling	Membrane Raft Assembly Nervous System Development Positive Regulation Of Toll-like Receptor Signaling Pathway
Drugs		Zonisamide	None
GWAS		Adult body size ( 32376654 ) Blood protein levels ( 30072576 ) Cardiac hypertrophy ( 21348951 ) Free thyroxine concentration ( 30367059 ) Height ( 31562340 ) Hemoglobin ( 32888494 ) High myopia ( 33830181 ) Myopia ( 27182965 ) Obesity-related traits ( 23251661 ) Parkinson's disease ( 27182965 ) Red blood cell count ( 32888494 ) Refractive error ( 32231278 ) Response to amphetamines ( 22952603 ) Schizophrenia ( 29483656 28991256 30285260 25056061 ) Spherical equivalent or myopia (age of diagnosis) ( 29808027 )	Brain morphology (MOSTest) ( 32665545 ) Macular thickness ( 30535121 ) Subcortical volume (MOSTest) ( 32665545 )
Novel Interactors		None recorded	1 novel interactors: PRKAR2B
Interacting Genes		14 interacting genes: CRX GGA2 HSD17B14 INTS7 ITPR1 KLHL8 LMNB2 LNX1 LRCH4 MAGED1 RAB34 SPDL1 STAT3 TBX3	16 interacting genes: CA8 CYB5R3 ELOVL7 HSD17B11 KASH5 KRT40 KRTAP10-7 KRTAP10-8 MDFI NOTCH2NLA RBBP6 RETREG3 RNASEK RTN4 SIN3A SPOP
Entrez ID		767	4034
HPRD ID		00266	10062
Ensembl ID		ENSG00000178538	ENSG00000077454
Uniprot IDs		P35219	B4DYF8 H7C5D9 O75427
PDB IDs		2W2J	Not available
GO Terms Enriched among Interactors		None	Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Keratin Filament