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KCNK15 and YWHAE
Number of citations of the paper that reports this interaction (PMID
12433946
)
25
Data Source:
HPRD
(two hybrid, in vivo)
KCNK15
YWHAE
Gene Name
potassium channel, two pore domain subfamily K, member 15
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Integral Component Of Membrane
Mitochondrion
Cytosol
Kinesin Complex
Focal Adhesion
Membrane
Axon
Cytoplasmic Vesicle Membrane
Melanosome
Extracellular Vesicular Exosome
Molecular Function
Voltage-gated Ion Channel Activity
Potassium Channel Activity
Protein Binding
Potassium Channel Regulator Activity
Enzyme Binding
Protein Domain Specific Binding
MHC Class II Protein Complex Binding
Histone Deacetylase Binding
Ion Channel Binding
Poly(A) RNA Binding
Protein Heterodimerization Activity
Phosphoserine Binding
Phosphoprotein Binding
Biological Process
Regulation Of Ion Transmembrane Transport
Potassium Ion Transmembrane Transport
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Neuron Migration
Regulation Of Heart Rate By Hormone
Protein Targeting
Apoptotic Process
Organelle Organization
Viral Process
Substantia Nigra Development
Hippocampus Development
Cerebral Cortex Development
Cellular Response To Heat
Hippo Signaling
Intracellular Signal Transduction
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Membrane Repolarization
Membrane Organization
Membrane Repolarization During Cardiac Muscle Cell Action Potential
Regulation Of Heart Rate By Cardiac Conduction
Apoptotic Signaling Pathway
Intrinsic Apoptotic Signaling Pathway
Regulation Of Cellular Response To Heat
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Regulation Of Potassium Ion Transmembrane Transporter Activity
Negative Regulation Of Peptidyl-serine Dephosphorylation
Pathways
HSF1 activation
Organelle biogenesis and maintenance
Translocation of GLUT4 to the plasma membrane
G2/M Transition
Activation of BH3-only proteins
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Programmed Cell Death
Recruitment of mitotic centrosome proteins and complexes
Intrinsic Pathway for Apoptosis
Signalling by NGF
Cell death signalling via NRAGE, NRIF and NADE
p75 NTR receptor-mediated signalling
Assembly of the primary cilium
Cellular response to heat stress
Regulation of HSF1-mediated heat shock response
Anchoring of the basal body to the plasma membrane
Cell Cycle, Mitotic
Activation of BAD and translocation to mitochondria
Signaling by Hippo
Loss of proteins required for interphase microtubule organization from the centrosome
Centrosome maturation
NADE modulates death signalling
Mitotic G2-G2/M phases
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
7 interactors:
SFN
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
107 interactors:
ABL1
ACD
AKAP13
ANKHD1-EIF4EBP3
ARHGEF2
ARHGEF28
ATXN1
BAD
BCR
CALM1
CAP2
CASP3
CDC25A
CDC25B
CDK11B
CDK14
CDK16
CDKN1B
CEP95
CGNL1
CHAF1A
COX2
DISC1
DYRK1A
ENKD1
EXO1
FAM13B
FAM53C
FTH1
GAPDH
GPRIN2
GRAP2
GSTA1
GTF2B
HDAC4
HDAC5
HIVEP2
HSF1
IGF1R
IL7R
ING1
IRS1
IRS2
KCNH2
KCNK15
KCNK3
KCNK9
KIAA0232
KIF1C
KRT18
LRMP
MAP3K1
MAP3K10
MAP3K2
MAP3K3
MAP3K5
MAPK7
MDM4
MSL2
MST1R
MYH10
NCOR2
NDEL1
NGFRAP1
PAPOLA
PNLIP
POT1
PRKCG
RAF1
RAP1GAP2
RASAL3
RASGRF1
REM1
RGS3
RIN1
RPGR
SAMSN1
SH3BP4
SLC8A1
SLC8A2
SLC8A3
SNCA
SORBS2
SRC
SSFA2
SYN2
TAF7
TAZ
TBC1D3F
TBP
TFDP2
TGFB1
TLK1
TNFAIP3
TOP2A
TSC1
TSC2
UBE3A
VIM
WNK1
WWTR1
YWHAB
YWHAG
YWHAH
YWHAQ
YWHAZ
ZNF839
Entrez ID
60598
7531
HPRD ID
09564
05457
Ensembl ID
ENSG00000108953
Uniprot IDs
Q9H427
P62258
PDB IDs
2BR9
3UAL
3UBW
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrion Organization
Regulation Of Mitochondrion Organization
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Intracellular Transport
Apoptotic Signaling Pathway
Positive Regulation Of Organelle Organization
Regulation Of Intracellular Transport
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Regulation Of Establishment Of Protein Localization
Positive Regulation Of Transport
Regulation Of Protein Localization
Membrane Organization
Regulation Of Organelle Organization
Apoptotic Process
Programmed Cell Death
Regulation Of Cellular Localization
Cell Death
Death
Positive Regulation Of Signal Transduction
Regulation Of Apoptotic Process
Regulation Of Cell Death
Intracellular Signal Transduction
Intracellular Protein Transport
Regulation Of Cellular Component Organization
Protein Targeting
Substantia Nigra Development
Cellular Protein Localization
Protein Transport
Regulation Of Signal Transduction
Establishment Of Protein Localization
Neural Nucleus Development
Intracellular Transport
Regulation Of Signaling
Negative Regulation Of Protein Dephosphorylation
Midbrain Development
Protein Localization
Establishment Of Localization In Cell
Cellular Localization
Signal Transduction
Hippo Signaling
Negative Regulation Of Cellular Protein Metabolic Process
Signaling
Cell Communication
Negative Regulation Of Protein Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of Catalytic Activity
Regulation Of Kinase Activity
Intracellular Signal Transduction
Cellular Response To Stimulus
Positive Regulation Of Catalytic Activity
Cell Communication
Regulation Of Protein Kinase Activity
Positive Regulation Of Cellular Metabolic Process
Regulation Of Phosphorus Metabolic Process
Signaling
Regulation Of Phosphorylation
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Metabolic Process
Response To Stimulus
Regulation Of Signaling
Regulation Of Protein Phosphorylation
Regulation Of Signal Transduction
Regulation Of Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Signal Transduction
Cellular Response To Organic Substance
Regulation Of Cellular Process
Cellular Response To Growth Factor Stimulus
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Response To Growth Factor
System Development
Neurotrophin TRK Receptor Signaling Pathway
Developmental Process
Neurotrophin Signaling Pathway
Negative Regulation Of Phosphorylation
Response To Organic Substance
Anatomical Structure Development
Multicellular Organismal Development
Apoptotic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Protein Phosphorylation
Response To Organonitrogen Compound
Programmed Cell Death
Regulation Of Cellular Component Organization
Cell Death
Death
Cellular Response To Organonitrogen Compound
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Hydrolase Activity
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Epidermal Growth Factor Receptor Signaling Pathway
Tagcloud
?
aberration
distinction
endometrial
ess
fam22
federation
girth
guiding
gynecology
hgus
hguss
hysterectomy
identifiable
immunomarker
jazf1
lymphadenectomy
meetings
multidisciplinary
obstetrics
oophorectomy
peritoneum
preferential
rearrangement
resemble
salpingo
sarcomas
staged
stroma
undifferentiated
Tagcloud (Difference)
?
aberration
distinction
endometrial
ess
fam22
federation
girth
guiding
gynecology
hgus
hguss
hysterectomy
identifiable
immunomarker
jazf1
lymphadenectomy
meetings
multidisciplinary
obstetrics
oophorectomy
peritoneum
preferential
rearrangement
resemble
salpingo
sarcomas
staged
stroma
undifferentiated
Tagcloud (Intersection)
?