XRCC3 and FANCG

Number of citations of the paper that reports this interaction (PMID 16621732)
11

Data Source:
HPRD (two hybrid, in vivo)

		XRCC3	FANCG
Gene Name		X-ray repair complementing defective repair in Chinese hamster cells 3	Fanconi anemia, complementation group G
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Replication Fork Cytoplasm Mitochondrion Rad51C-XRCC3 Complex Perinuclear Region Of Cytoplasm	Nucleoplasm Nucleolus Cytoplasm Mitochondrion Plasma Membrane Fanconi Anaemia Nuclear Complex
	Molecular Function	Four-way Junction DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Crossover Junction Endodeoxyribonuclease Activity	Damaged DNA Binding Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Catabolic Process, Endonucleolytic DNA Repair DNA Recombination Cellular Response To DNA Damage Stimulus Response To Organic Substance Regulation Of Centrosome Duplication Resolution Of Mitotic Recombination Intermediates Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint	Cell Cycle Checkpoint Ovarian Follicle Development DNA Repair Mitochondrion Organization Spermatid Development Response To Radiation
Pathways			Fanconi Anemia pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: FANCG RAD51C RAD51D SWSAP1 ZNHIT3 ZSWIM7	22 interactors: BRCA2 BRCC3 CAPN1 CDK1 CYP19A1 CYP2E1 ERCC4 FANCA FANCC FANCE FANCF FTSJ3 GABPB1 HES1 KRT19 PSMB1 RTN2 SAMD3 UIMC1 USHBP1 XRCC3 ZBED1
Entrez ID		7517	2189
HPRD ID		07201	04262
Ensembl ID		ENSG00000126215	ENSG00000221829
Uniprot IDs		O43542 Q53XC8	O15287 Q53XM5
PDB IDs
Enriched GO Terms of Interacting Partners?		Double-strand Break Repair Via Homologous Recombination Recombinational Repair Double-strand Break Repair DNA Repair DNA Recombination Cellular Response To DNA Damage Stimulus DNA Metabolic Process Cellular Response To Stress Reciprocal Meiotic Recombination Protein Stabilization Meiosis I Response To Stress Female Meiosis Sister Chromatid Cohesion Strand Invasion Regulation Of Protein Stability Meiotic Nuclear Division Meiotic Cell Cycle Nucleobase-containing Compound Metabolic Process Meiotic Sister Chromatid Cohesion Reproduction Cell Cycle Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cell Cycle Nitrogen Compound Metabolic Process Posttranscriptional Regulation Of Gene Expression Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Spermatogenesis Male Gamete Generation Sister Chromatid Cohesion Male Meiosis I Cellular Response To Stimulus Female Meiotic Division Gamete Generation Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Male Meiosis Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Ovarian Follicle Development Telomere Maintenance Meiotic Chromosome Segregation Response To Stimulus Sister Chromatid Segregation DNA Catabolic Process, Endonucleolytic Chromosome Organization	Cellular Response To DNA Damage Stimulus DNA Repair DNA Metabolic Process Cellular Response To Stress Double-strand Break Repair Developmental Process Involved In Reproduction Heterocycle Metabolic Process Histone H2A K63-linked Deubiquitination Reproductive Structure Development Reproductive System Development Positive Regulation Of Mitotic Cell Cycle Single Organism Reproductive Process G2 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Response To Stress Cellular Nitrogen Compound Metabolic Process Reproductive Process DNA Damage Checkpoint Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Double-strand Break Repair Via Homologous Recombination Recombinational Repair Nucleotide-excision Repair Cell Cycle Cellular Response To Stimulus Protein K63-linked Deubiquitination Female Gonad Development Development Of Primary Female Sexual Characteristics Histone Deubiquitination Cellular Metabolic Process Reproduction Cell Cycle Process Response To Stimulus Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Histone Modification Response To X-ray Meiotic Nuclear Division Muscle Cell Development Positive Regulation Of DNA Repair Response To Radiation Response To Reactive Oxygen Species Meiotic Cell Cycle Regulation Of Cell Cycle Gonad Development Nucleotide-excision Repair Involved In Interstrand Cross-link Repair Negative Regulation Of Stomach Neuroendocrine Cell Differentiation
Tagcloud ?		additive allele applying became bonferroni correction d312n damaged dominant ercc2 ethnical exoi gg insignificant polymorphism polymorphisms r399q recessive remaining repair rs1799793 rs25487 russian russians snps tt xrcc1 xrcc2	24h 300mum 513a 5p abp aminobiphenyl array arrays arylamine bioinformatic carcinogen comet damage deregulation eventually exo1 hepg2 lig1 mirna mirnas parallel pcna pcr qrt rad18 repair ung validated xrcc2
Tagcloud (Difference) ?		additive allele applying became bonferroni correction d312n damaged dominant ercc2 ethnical exoi gg insignificant polymorphism polymorphisms r399q recessive remaining rs1799793 rs25487 russian russians snps tt xrcc1	24h 300mum 513a 5p abp aminobiphenyl array arrays arylamine bioinformatic carcinogen comet damage deregulation eventually exo1 hepg2 lig1 mirna mirnas parallel pcna pcr qrt rad18 ung validated
Tagcloud (Intersection) ?		repair xrcc2