XRCC3

Gene Name		X-ray repair complementing defective repair in Chinese hamster cells 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Replication Fork Cytoplasm Mitochondrion Rad51C-XRCC3 Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Four-way Junction DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Crossover Junction Endodeoxyribonuclease Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Catabolic Process, Endonucleolytic DNA Repair DNA Recombination Cellular Response To DNA Damage Stimulus Response To Organic Substance Regulation Of Centrosome Duplication Resolution Of Mitotic Recombination Intermediates Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: FANCG RAD51C RAD51D SWSAP1 ZNHIT3 ZSWIM7
Entrez ID		7517
HPRD ID		07201
Ensembl ID		ENSG00000126215
Uniprot IDs		O43542 Q53XC8
PDB IDs
Enriched GO Terms of Interacting Partners?		Double-strand Break Repair Via Homologous Recombination Recombinational Repair Double-strand Break Repair DNA Repair DNA Recombination Cellular Response To DNA Damage Stimulus DNA Metabolic Process Cellular Response To Stress Reciprocal Meiotic Recombination Protein Stabilization Meiosis I Response To Stress Female Meiosis Sister Chromatid Cohesion Strand Invasion Regulation Of Protein Stability Meiotic Nuclear Division Meiotic Cell Cycle Nucleobase-containing Compound Metabolic Process Meiotic Sister Chromatid Cohesion Reproduction Cell Cycle Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cell Cycle Nitrogen Compound Metabolic Process Posttranscriptional Regulation Of Gene Expression Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Spermatogenesis Male Gamete Generation Sister Chromatid Cohesion Male Meiosis I Cellular Response To Stimulus Female Meiotic Division Gamete Generation Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Male Meiosis Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Ovarian Follicle Development Telomere Maintenance Meiotic Chromosome Segregation Response To Stimulus Sister Chromatid Segregation DNA Catabolic Process, Endonucleolytic Chromosome Organization
Tagcloud ?		additive allele applying became bonferroni correction d312n damaged dominant ercc2 ethnical exoi gg insignificant polymorphism polymorphisms r399q recessive remaining repair rs1799793 rs25487 russian russians snps tt xrcc1 xrcc2