XRCC3 and ITIH5

Number of citations of the paper that reports this interaction (PubMedID 25640309)
0

Data Source:
BioGRID (two hybrid)

		XRCC3	ITIH5
Description		X-ray repair cross complementing 3	inter-alpha-trypsin inhibitor heavy chain 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Replication Fork Cytoplasm Mitochondrion Cytosol Rad51C-XRCC3 Complex Perinuclear Region Of Cytoplasm	Extracellular Region Extracellular Matrix
	Molecular Function	Nucleotide Binding Four-way Junction DNA Binding DNA Binding Protein Binding ATP Binding Crossover Junction DNA Endonuclease Activity ATP-dependent DNA Damage Sensor Activity	Serine-type Endopeptidase Inhibitor Activity Peptidase Inhibitor Activity
	Biological Process	Telomere Maintenance Via Recombination Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Recombination DNA Damage Response Regulation Of Centrosome Duplication Interstrand Cross-link Repair Double-strand Break Repair Via Synthesis-dependent Strand Annealing Resolution Of Mitotic Recombination Intermediates Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint T-circle Formation Telomeric Loop Disassembly Telomere Maintenance Via Telomere Trimming	Hyaluronan Metabolic Process
Pathways		HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 26426971 29273807) Schizophrenia ( 25056061 29483656)	Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Left–right brain asymmetry ( 33723403) Metabolite levels ( 23823483) Planum temporale asymmetry index ( 31887566)
Interacting Genes		22 interacting genes: BAP1 BCAS3 CXCL1 FANCG GREB1 ITIH5 LRATD2 MRC2 OSGIN1 PALB2 PSMC3IP RAD51 RAD51C RAD51D RNF20 SCGB3A1 SERPINB5 SNAI1 SWSAP1 TFF1 ZNHIT3 ZSWIM7	10 interacting genes: BAG4 BRCA1 CHEK2 ESR2 HMMR NOTCH2 PPM1D RAD51 RB1CC1 XRCC3
Entrez ID		7517	80760
HPRD ID		07201	13747
Ensembl ID		ENSG00000126215	ENSG00000123243
Uniprot IDs		O43542 Q53XC8	A0A096LP62 C9J2H1 G5E9D8 Q86UX2 Q96JW9
PDB IDs
Enriched GO Terms of Interacting Partners?		Recombinational Repair DNA Strand Invasion Double-strand Break Repair Via Homologous Recombination DNA Recombination Reciprocal Meiotic Recombination Homologous Recombination Double-strand Break Repair Telomere Maintenance Via Recombination ATP-dependent DNA Damage Sensor Activity Shu Complex Mitotic Recombination DNA Metabolic Process DNA Repair Rad51B-Rad51C-Rad51D-XRCC2 Complex DNA Recombinase Assembly Interstrand Cross-link Repair DNA Damage Response Meiosis I Cell Cycle Process Four-way Junction DNA Binding Telomere Maintenance Single-stranded DNA Binding Nucleic Acid Metabolic Process Telomere Organization Replication Fork ATP-dependent Activity, Acting On DNA Reproductive Process Growth Factor Activity Response To Glucoside Chromosome Organization Meiosis I Female Meiosis Sister Chromatid Cohesion Nucleate Erythrocyte Differentiation Thrombocyte Differentiation Meiotic Joint Molecule Formation DNA Recombinase Auxiliary Factor Complex Recombinase Activator Activity Meiotic Strand Invasion Involved In Reciprocal Meiotic Recombination Histone H2B C-terminal K Residue Ubiquitin Ligase Activity Condensed Nuclear Chromosome Mitotic Recombination-dependent Replication Fork Processing DNA Strand Exchange Activity Chromosome Organization Involved In Meiotic Cell Cycle Presynaptic Intermediate Filament Cytoskeleton Rad51C-XRCC3 Complex Meiotic DNA Recombinase Assembly Mesoderm Development Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Macrophage Homeostasis Cellular Response To Stress Nucleobase-containing Compound Metabolic Process	Regulation Of DNA Damage Checkpoint Regulation Of Intracellular Signal Transduction Nuclear Ubiquitin Ligase Complex Double-strand Break Repair Response To Glycoside Cellular Response To Ionizing Radiation Lateral Element Regulation Of Signal Transduction Telomere Maintenance Via Recombination Enzyme Binding DNA Damage Response Double-strand Break Repair Via Homologous Recombination ATP-dependent DNA Damage Sensor Activity Mitotic Recombination Recombinational Repair Regulation Of Cell Communication Response To Radiation Response To Ionizing Radiation Regulation Of Cell Cycle Phase Transition Signal Transduction In Response To DNA Damage Regulation Of Signaling Cellular Response To Radiation Cellular Response To Gamma Radiation Chromosome, Telomeric Region DNA Repair Condensed Chromosome Homologous Recombination Interstrand Cross-link Repair DNA Recombination DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Centrosome Duplication Condensed Nuclear Chromosome Male Germ Cell Nucleus G2/M Transition Of Mitotic Cell Cycle Response To Gamma Radiation Response To Stress Cell Cycle G2/M Phase Transition Regulation Of Centrosome Cycle DNA Metabolic Process Regulation Of Cell Cycle Process Response To Glucoside Negative Regulation Of MRNA Modification Ribophagy Ubiquitin Protein Ligase Binding Regulation Of Apoptotic Process Apoptotic Signaling Pathway Mitotic DNA Damage Checkpoint Signaling Mitotic DNA Integrity Checkpoint Signaling Regulation Of Programmed Cell Death Nucleus
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?