XRCC3 and RAD51D

Number of citations of the paper that reports this interaction (PMID 11744692)
24

Data Source:
HPRD (in vivo, in vitro)

		XRCC3	RAD51D
Gene Name		X-ray repair complementing defective repair in Chinese hamster cells 3	RAD51 paralog D
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Replication Fork Cytoplasm Mitochondrion Rad51C-XRCC3 Complex Perinuclear Region Of Cytoplasm	Chromosome, Telomeric Region Nucleus Replication Fork Cytoplasm Centrosome Rad51B-Rad51C-Rad51D-XRCC2 Complex
	Molecular Function	Four-way Junction DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Crossover Junction Endodeoxyribonuclease Activity	Four-way Junction DNA Binding DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Gamma-tubulin Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Catabolic Process, Endonucleolytic DNA Repair DNA Recombination Cellular Response To DNA Damage Stimulus Response To Organic Substance Regulation Of Centrosome Duplication Resolution Of Mitotic Recombination Intermediates Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint	Telomere Maintenance Double-strand Break Repair Via Homologous Recombination DNA Repair Reciprocal Meiotic Recombination Strand Invasion
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: FANCG RAD51C RAD51D SWSAP1 ZNHIT3 ZSWIM7	17 interactors: AMOTL2 BLM C1orf94 CEP57L1 IKZF1 IKZF3 KIFC3 KRT15 LNX1 LZTS2 PRDM14 RAD51B RAD51C SWSAP1 XRCC2 XRCC3 ZSWIM7
Entrez ID		7517	5892
HPRD ID		07201	04261
Ensembl ID		ENSG00000126215	ENSG00000185379
Uniprot IDs		O43542 Q53XC8	O75771
PDB IDs			2KZ3
Enriched GO Terms of Interacting Partners?		Double-strand Break Repair Via Homologous Recombination Recombinational Repair Double-strand Break Repair DNA Repair DNA Recombination Cellular Response To DNA Damage Stimulus DNA Metabolic Process Cellular Response To Stress Reciprocal Meiotic Recombination Protein Stabilization Meiosis I Response To Stress Female Meiosis Sister Chromatid Cohesion Strand Invasion Regulation Of Protein Stability Meiotic Nuclear Division Meiotic Cell Cycle Nucleobase-containing Compound Metabolic Process Meiotic Sister Chromatid Cohesion Reproduction Cell Cycle Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cell Cycle Nitrogen Compound Metabolic Process Posttranscriptional Regulation Of Gene Expression Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Spermatogenesis Male Gamete Generation Sister Chromatid Cohesion Male Meiosis I Cellular Response To Stimulus Female Meiotic Division Gamete Generation Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Male Meiosis Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Ovarian Follicle Development Telomere Maintenance Meiotic Chromosome Segregation Response To Stimulus Sister Chromatid Segregation DNA Catabolic Process, Endonucleolytic Chromosome Organization See more	Double-strand Break Repair Via Homologous Recombination Recombinational Repair Double-strand Break Repair DNA Recombination DNA Repair Cellular Response To DNA Damage Stimulus DNA Metabolic Process Cellular Response To Stress Organelle Organization Positive Regulation Of Mitotic Cell Cycle DNA Catabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Cell Cycle Nucleobase-containing Compound Metabolic Process Meiotic Nuclear Division Response To X-ray Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Meiotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Reciprocal Meiotic Recombination Positive Regulation Of Cell Cycle Process Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Neutrophil Differentiation Histone H3-R26 Methylation Inner Cell Mass Cell Fate Commitment Nitrogen Compound Metabolic Process Positive Regulation Of Cell Cycle Nucleic Acid Phosphodiester Bond Hydrolysis Microtubule-based Process Female Meiosis Sister Chromatid Cohesion Resolution Of Mitotic Recombination Intermediates Resolution Of Recombination Intermediates Strand Invasion DNA Catabolic Process, Endonucleolytic Protein Stabilization Zonula Adherens Maintenance Cellular Response To Camptothecin Cellular Response To Hydroxyurea Cellular Macromolecule Catabolic Process Regulation Of Lymphocyte Activation Meiosis I Lymphocyte Activation Response To Camptothecin Negative Regulation Of Mitotic Recombination Microtubule Cytoskeleton Organization See more
Tagcloud ?		additive allele applying became bonferroni correction d312n damaged dominant ercc2 ethnical exoi gg insignificant polymorphism polymorphisms r399q recessive remaining repair rs1799793 rs25487 russian russians snps tt xrcc1 xrcc2	altogether anything atm brca2 brip1 chek2 confer dysfunctional exons germline harbor heritability hrr inherited junction missense palb2 paralogs postulated private silent splice substitutions tolerates unexplained variants xrcc2
Tagcloud (Difference) ?		additive allele applying became bonferroni correction d312n damaged dominant ercc2 ethnical exoi gg insignificant polymorphism polymorphisms r399q recessive remaining repair rs1799793 rs25487 russian russians snps tt xrcc1	altogether anything atm brca2 brip1 chek2 confer dysfunctional exons germline harbor heritability hrr inherited junction missense palb2 paralogs postulated private silent splice substitutions tolerates unexplained variants
Tagcloud (Intersection) ?		xrcc2