FEN1 and GSK3B

  • Number of citations of the paper that reports this interaction (PMID 21900206)
  • 27
  • Data Source:
  • BioGRID (two hybrid)

FEN1

GSK3B

Gene Name flap structure-specific endonuclease 1 glycogen synthase kinase 3 beta
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Metabolite levels ( 23378610)
  • Oleic acid (18:1n-9) plasma levels ( 23362303)
  • Palmitoleic acid (16:1n-7) plasma levels ( 23362303)
  • Phospholipid levels (plasma) ( 21829377)
  • Platelet counts ( 22139419)
  • Stearic acid (18:0) plasma levels ( 23362303)
Protein-Protein Interactions 15 interactors: APEX1 APP ARHGDIA BLM CCNA2 CDK1 CDK2 EEF1G EP300 GSK3B HNRNPA1 PCNA RAD1 TERF1 WRN 206 interactors: ACLY ACSBG1 ACTL6B ADAP1 ADIRF AKAP11 AKT1 AKT2 AKT3 APC APP AR ARRB1 ASRGL1 ATPIF1 ATXN3 AURKA AXIN1 AXIN2 BAG6 BCL3 BEX1 BICD1 BICD2 BRIX1 BTRC BZW2 C14orf1 CABYR CAMSAP3 CCND1 CCNE1 CDH1 CDK5 CDX2 CEBPA CEBPZ CENPB CHD3 CIITA CLEC3B CREB1 CREM CSAD CST6 CTNNB1 CTNND1 DBI DCTN1 DCTN2 DCTN3 DDIT4 DEAF1 DEFA1 DHX34 DNAJC13 DNM1L DNMT1 DNMT3L DPYSL2 DUSP9 DYNC1I1 E2F1 EEF1A1 EEF1G EFTUD2 EIF2B5 EIF4EBP1 ENTPD6 EYA1 FAM193B FAM83D FBN3 FEN1 FIBP FKBP14 FOXO1 FRAT1 FRAT2 FZD5 GAPDH GBP2 GIPC1 GJB5 GNB2 GPR39 GYS1 HDAC4 HNRNPD HSP90AA1 HSPA4 IGHM IGSF21 IKBKG ILK IQCG JUN KHSRP KIAA1191 KIF5B KLF2 KLF5 LMO4 LRP6 LUC7L2 MAP1B MAP3K1 MAP3K4 MAP4 MAPK1 MAPT MARK2 MASP1 MCL1 MDM2 MED24 MGEA5 MICAL1 MID1IP1 MITF MPP1 MTF2 MTOR MUC1 MYC MYOCD NAT9 NBR1 NCOA3 NFE2L1 NFE2L2 NFKB1 NIN NOTCH1 NOTCH2 NRBP1 NSFL1C OGT PDE4D PFKFB4 PHLPP1 PIK3R1 PIM2 PMAIP1 PPARGC1A PPP1R2 PRKACA PRKCA PRKCB PRKCZ PRKDC PSEN1 PTK2 PTN PTPN1 PXN QARS RAI1 RBPJ RCAN1 RELB RICTOR RPL36AL RPLP1 RPS2 RPS6KA1 RSU1 RXRA SAP30BP SGK1 SGK3 SLA SMAD1 SMAD3 SNAI1 SNCA SNCAIP SPTBN4 SREBF1 SYNE4 TAZ TLE1 TMEM132A TMEM44 TONSL TP53 TPPP TSC2 TUBA1A UBE2D1 UBR1 UBR5 UBXN6 UFM1 UPF3A VIM VPS51 WSB1 XPNPEP1 YBX1 YBX3 ZFPM1 ZHX1 ZNF135 ZNF227 ZNF746
Entrez ID 2237 2932
HPRD ID 02670 05418
Ensembl ID ENSG00000168496 ENSG00000082701
Uniprot IDs P39748 Q6FHX6 P49841 Q6FI27
PDB IDs 1U7B 1UL1 3Q8K 3Q8L 3Q8M 3UVU 1GNG 1H8F 1I09 1J1B 1J1C 1O6K 1O6L 1O9U 1PYX 1Q3D 1Q3W 1Q41 1Q4L 1Q5K 1R0E 1UV5 2JDO 2JDR 2JLD 2O5K 2OW3 2UW9 2X39 2XH5 3CQU 3CQW 3DU8 3E87 3E88 3E8D 3F7Z 3F88 3GB2 3I4B 3L1S 3M1S 3PUP 3Q3B 3SAY 3SD0 3ZDI 3ZRK 3ZRL 3ZRM 4ACC 4ACD 4ACG 4ACH 4AFJ 4B7T 4DIT 4EKK 4IQ6 4J1R 4J71
Enriched GO Terms of Interacting Partners?
Tagcloud ?
alka  alphaherpesvirus  analogy  backbone  cnjb  complexed  contrasts  crystallographic  emb  endonuclease  helical  helix  hhh  kinesin  kraut  kumar  motifs  nitrogens  nuclease  pelletier  pol  primer  sawaya  searches  shutoff  spt6  taq  virion  wilson 
200mg  clamp  coagulation  confirmation  dm  downregulated  encountered  f3  gskbeta3  hg  hi  hour  hyperglycemia  hyperinsulinemia  ingenuity  monocyte  monocytes  pik3c3  platelet  platelets  proinflammatory  prothrombotic  ptpn1  ptpn11  qrt  stxbp4  tf  tfpi  thrombin 
Tagcloud (Difference) ?
alka  alphaherpesvirus  analogy  backbone  cnjb  complexed  contrasts  crystallographic  emb  endonuclease  helical  helix  hhh  kinesin  kraut  kumar  motifs  nitrogens  nuclease  pelletier  pol  primer  sawaya  searches  shutoff  spt6  taq  virion  wilson 
200mg  clamp  coagulation  confirmation  dm  downregulated  encountered  f3  gskbeta3  hg  hi  hour  hyperglycemia  hyperinsulinemia  ingenuity  monocyte  monocytes  pik3c3  platelet  platelets  proinflammatory  prothrombotic  ptpn1  ptpn11  qrt  stxbp4  tf  tfpi  thrombin 
Tagcloud (Intersection) ?