VIPR2 and ERBB2IP

Number of citations of the paper that reports this interaction (PMID 15123239)
9

Data Source:
BioGRID (unspecified method)

		VIPR2	ERBB2IP
Gene Name		vasoactive intestinal peptide receptor 2	erbb2 interacting protein
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Basement Membrane Nucleus Nucleoplasm Cytoplasm Plasma Membrane Basal Plasma Membrane Cell Junction Hemidesmosome Nuclear Membrane
	Molecular Function	G-protein Coupled Receptor Activity Vasoactive Intestinal Polypeptide Receptor Activity	ErbB-2 Class Receptor Binding Integrin Binding Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Signal Transduction G-protein Coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Cell-cell Signaling Negative Regulation Of Smooth Muscle Cell Proliferation	Protein Targeting Cell Cycle Cell Adhesion Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell Growth Intermediate Filament Cytoskeleton Organization Basal Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Pathways		Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events	Signaling by ERBB2
Drugs
Diseases
GWAS		Myopia (pathological) ( 23406873)
Protein-Protein Interactions		4 interactors: ADCYAP1 APP ERBB2IP VIP	62 interactors: ABCA1 ABCC4 ABR ACTN1 ACTN2 ACVR2A ACVR2B AGTR2 APC ARHGEF7 ARVCF ATP2B1 ATP2B2 ATP2B4 BANF1 CASK CDH1 CHUK COPB1 CTNNB1 CTNND1 CTNND2 CTSG DLG4 DST ERBB2 FOXO3 GRIN2B GRIN2C GUCY1A2 ITGB4 KCNA4 KCNA5 LAMB1 LMO1 LMO2 LRRC1 MAP4 MAPK12 MCC MEF2A MPP1 MPP2 MPP3 NOD2 NR2E1 PICK1 PKP4 RAF1 SCN4A SHOC2 SLC5A5 SLC5A6 SLC6A12 SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 STAT3 VIPR2 ZFYVE9
Entrez ID		7434	55914
HPRD ID		03576	06090
Ensembl ID		ENSG00000106018	ENSG00000112851
Uniprot IDs		P41587 Q6ZN22	B4DIP2 Q96RT1
PDB IDs		2X57	1MFG 1MFL 1N7T 2H3L 2QBW 3CH8
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Potassium Ion Transport Positive Regulation Of Vasodilation Positive Regulation Of Adenylate Cyclase Activity Regulation Of Vasodilation Positive Regulation Of Lyase Activity Single-organism Behavior Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase Activity Regulation Of Potassium Ion Transport Positive Regulation Of CAMP Biosynthetic Process Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Behavior Positive Regulation Of Cyclic Nucleotide Metabolic Process Secretion Regulation Of CAMP Biosynthetic Process Negative Regulation Of Ion Transport Regulation Of CAMP Metabolic Process Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Somatostatin Secretion Negative Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cell Growth Cell Surface Receptor Signaling Pathway Basal Protein Localization Synaptic Growth At Neuromuscular Junction Neurological System Process Collateral Sprouting In Absence Of Injury Positive Regulation Of Protein Metabolic Process Learning Or Memory Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Negative Regulation Of Neurogenesis Cognition Cellular Calcium Ion Homeostasis Prolactin Secretion Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Phosphorus Metabolic Process Calcium Ion Homeostasis Positive Regulation Of Catalytic Activity Axon Choice Point Recognition Negative Regulation Of Cell Development Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Penile Erection Positive Regulation Of Growth Hormone Secretion Neuron Remodeling Negative Regulation Of Transport See more	Regulation Of Signaling Response To Stimulus Response To Organic Substance Signaling Cellular Response To Growth Factor Stimulus Cell Communication Response To Growth Factor Cellular Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Response To Stress Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Positive Regulation Of Cellular Biosynthetic Process Cell Junction Assembly Regulation Of Cell Proliferation SMAD Protein Complex Assembly Negative Regulation Of Cell Proliferation Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Movement Signal Transduction Cellular Response To Organic Cyclic Compound Organ Development Anatomical Structure Morphogenesis Cellular Component Assembly Cell-cell Junction Organization Positive Regulation Of Transcription, DNA-templated Renal System Development Negative Regulation Of Signaling Regulation Of Cell Motility Gastrulation Cell-cell Signaling Regulation Of Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Locomotion Response To Wounding Urogenital System Development Regulation Of Cell Migration System Development Regulation Of Epithelial Cell Proliferation Adherens Junction Organization Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Multicellular Organismal Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Kidney Development Positive Regulation Of Gene Expression Response To Organic Cyclic Compound Neurotrophin TRK Receptor Signaling Pathway See more
Tagcloud ?		7q36 7qter affymetrix arise asymptomatic boy condensin delay deletion deletions dysmorphism encompassing esyt2 father grandfather harbored heterozygosity inherited mcph1 microcephaly mother ncapg2 novo paternal prenatal psychomotor retardation snp wdr60	adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer
Tagcloud (Difference) ?		7q36 7qter affymetrix arise asymptomatic boy condensin delay deletion deletions dysmorphism encompassing esyt2 father grandfather harbored heterozygosity inherited mcph1 microcephaly mother ncapg2 novo paternal prenatal psychomotor retardation snp wdr60	adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer
Tagcloud (Intersection) ?