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SUMO1 and TFCP2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SUMO1
TFCP2
Gene Name
small ubiquitin-like modifier 1
transcription factor CP2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Fibrillar Center
Nucleus
Nuclear Pore
Nucleoplasm
Nucleolus
Cytoplasm
PML Body
Nuclear Speck
Dendrite
Nuclear Membrane
Synapse
Cellular_component
Nucleus
Molecular Function
Protein Binding
Transcription Factor Binding
SUMO Transferase Activity
Ubiquitin Protein Ligase Binding
Poly(A) RNA Binding
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Sequence-specific DNA Binding
Biological Process
DNA Repair
Protein Sumoylation
Cytokine-mediated Signaling Pathway
PML Body Organization
Positive Regulation Of Protein Complex Assembly
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Localization
Negative Regulation Of DNA Binding
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Post-translational Protein Modification
Cellular Protein Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Palate Development
Interferon-gamma-mediated Signaling Pathway
Regulation Of Interferon-gamma-mediated Signaling Pathway
Protein Localization To Nuclear Pore
Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Interferon gamma signaling
SUMO is proteolytically processed
Post-translational protein modification
SUMOylation
Interferon Signaling
Cytokine Signaling in Immune system
SUMO is conjugated to E1 (UBA2:SAE1)
Regulation of IFNG signaling
SUMO is transferred from E1 to E2 (UBE2I, UBC9)
Processing and activation of SUMO
Drugs
Diseases
GWAS
Protein-Protein Interactions
194 interactors:
ADD3
APP
AR
ARL13A
ATF2
ATF3
ATXN1
ATXN3
ATXN7
AURKA
AURKB
BCAM
BCL11A
BIRC3
BLM
BRCA1
C11orf65
C18orf25
CAMSAP2
CARD9
CASP2
CASP8
CCDC67
CD40
CDCA8
CHAF1A
CHD3
CHD4
COG1
CTNNA1
DAXX
DDX24
DNM1
DNMT3A
DNMT3B
DTX2
EDARADD
ESR1
ETV1
ETV4
ETV6
FADD
FAM118B
FANCM
FAS
FASLG
FBF1
FLI1
FOS
FOXL2
FOXM1
GATA1
GLP1R
GMCL1
HDAC4
HDAC9
HGS
HIF1A
HIPK2
HIPK3
HIRA
HNF4A
HNRNPC
HNRNPK
HSF1
HSF2
HTT
ING2
IRAK1
JUN
KAT2A
KAT6B
KDM1A
KRT14
KRT18
KRT5
KRT8
MAP2K1
MAPK1IP1L
MDC1
MDM2
MECOM
MEF2A
MEF2C
MITF
MKL1
MSX1
MUL1
MX1
MYB
NCOA1
NCOA2
NCOA3
NCOR2
NELFE
NFE2L2
NFKBIA
NIN
NOS1
NOX5
NR3C1
NR3C2
PARK7
PARP1
PAX6
PDGFC
PHC1
PIAS1
PIAS2
PIAS3
PIAS4
PIK3C3
PLK3
PML
PPARA
PPM1J
RAD51
RAD52
RAD54B
RAD54L2
RANBP2
RANGAP1
RB1
RBM25
RHOXF2
RNF4
RPS3
SAE1
SALL1
SART1
SATB1
SEMA6A
SENP1
SENP2
SENP6
SETX
SH3KBP1
SLC2A1
SOX10
SOX2
SOX6
SP1
SP100
SP3
SREBF1
SREBF2
SSRP1
STAB2
STK24
STMN2
SUMO1P1
SUMO2
SUPT7L
SYMPK
TCERG1
TCF4
TDG
TDP2
TFCP2
TGM2
TNFRSF1A
TOE1
TOP1
TOP2A
TOP2B
TOPORS
TP53
TP73
TRAF4
TRIM24
TRIM5
TRPS1
TSC22D3
TSHZ2
TSNAX
UBA2
UBE2I
USP25
USP7
USPL1
WNK1
WRN
XRCC1
XRCC5
ZBTB16
ZBTB26
ZBTB6
ZBTB7A
ZCCHC12
ZCCHC7
ZMYM2
ZMYM5
ZNF24
ZNF451
62 interactors:
ADPRH
APBB1
ASAP3
BAG6
C19orf73
CA1
CASP8
CBX8
CCDC94
CDC73
COIL
DNAJC27
DNAJC5B
DPH1
E2F8
EAF1
EIF5B
EPHA10
FAM64A
FANCL
FARS2
FBXL18
GPANK1
HDAC1
HDAC2
IRAK1BP1
KIAA1598
MAPK1
MAPK14
MAPK8
MOB3C
MORF4L1
MRPL11
MRPL40
MVP
NABP1
NFE4
NOM1
NPEPL1
PHF1
PITPNM1
PLCB1
POLL
POLR3GL
PPIG
PPP1R1B
PPP3R2
PSMD5
RBMS1
RNF2
SDCBP
SIN3A
STMN2
SUMO1
TCEA2
TDRD1
TRAPPC12
TSPAN12
UBP1
YY1
ZCCHC10
ZCCHC12
Entrez ID
7341
7024
HPRD ID
03554
01790
Ensembl ID
ENSG00000116030
ENSG00000135457
Uniprot IDs
P63165
Q12800
PDB IDs
1A5R
1TGZ
1WYW
1Y8R
1Z5S
2ASQ
2BF8
2G4D
2IO2
2IY0
2IY1
2KQS
2LAS
2PE6
2UYZ
2VRR
3KYC
3KYD
3RZW
3UIP
Enriched GO Terms of Interacting Partners
?
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
RNA Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Transcription, DNA-templated
Positive Regulation Of Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Metabolic Process
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Gene Expression
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Macromolecule Biosynthetic Process
Negative Regulation Of RNA Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Cellular Metabolic Process
Transcription From RNA Polymerase II Promoter
Regulation Of Cell Death
Regulation Of Apoptotic Process
Biosynthetic Process
Cellular Metabolic Process
Regulation Of Cellular Process
Organelle Organization
Chromosome Organization
Cellular Response To Organic Substance
Protein Sumoylation
Cellular Response To Stimulus
Response To Organic Substance
Response To Stimulus
Developmental Process
Programmed Cell Death
Apoptotic Process
Peptidyl-lysine Modification
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
RNA Metabolic Process
Transcription, DNA-templated
Nucleobase-containing Compound Metabolic Process
RNA Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Nitrogen Compound Metabolic Process
Cellular Response To DNA Damage Stimulus
Cellular Metabolic Process
Cellular Response To Stress
Chromatin Modification
Cellular Protein Metabolic Process
Histone Modification
Chromatin Organization
Negative Regulation Of Gene Expression
Cell Cycle
Negative Regulation Of Cellular Metabolic Process
Protein Metabolic Process
Histone Deacetylation
Regulation Of Gene Expression
Chromosome Organization
Regulation Of Metabolic Process
Protein Deacetylation
TRIF-dependent Toll-like Receptor Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Regulation Of Innate Immune Response
Activation Of Innate Immune Response
Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Response To Stimulus
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Biosynthetic Process
Regulation Of Organelle Organization
Negative Regulation Of Gene Expression, Epigenetic
Cellular Protein Modification Process
Negative Regulation Of RNA Biosynthetic Process
Peptidyl-amino Acid Modification
Toll-like Receptor 4 Signaling Pathway
Anatomical Structure Development
Anatomical Structure Morphogenesis
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Tagcloud
?
aphidicolin
attachment
break
breakage
budding
cfs
covalent
excessive
fields
fragile
hallmark
modifier
ortholog
perturbed
pol32
pold3
polypeptides
proteomic
recombinational
replication
resource
rpa
ssdna
stresses
subfamily
sumo2
sumo3
sumoylation
Tagcloud (Difference)
?
aphidicolin
attachment
break
breakage
budding
cfs
covalent
excessive
fields
fragile
hallmark
modifier
ortholog
perturbed
pol32
pold3
polypeptides
proteomic
recombinational
replication
resource
rpa
ssdna
stresses
subfamily
sumo2
sumo3
sumoylation
Tagcloud (Intersection)
?