SUMO1 and RPS3

Number of citations of the paper that reports this interaction (PMID 21968017)
2

Data Source:
BioGRID (pull down)

		SUMO1	RPS3
Gene Name		small ubiquitin-like modifier 1	ribosomal protein S3
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Gene Ontology Annotations	Cellular Component	Fibrillar Center Nucleus Nuclear Pore Nucleoplasm Nucleolus Cytoplasm PML Body Nuclear Speck Dendrite Nuclear Membrane Synapse	Nucleus Nucleolus Cytoplasm Mitochondrial Inner Membrane Spindle Cytosol Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit Ribonucleoprotein Complex Ruffle Membrane Extracellular Vesicular Exosome NF-kappaB Complex
	Molecular Function	Protein Binding Transcription Factor Binding SUMO Transferase Activity Ubiquitin Protein Ligase Binding Poly(A) RNA Binding	Damaged DNA Binding MRNA Binding Structural Constituent Of Ribosome DNA-(apurinic Or Apyrimidinic Site) Lyase Activity Protein Binding Oxidized Purine Nucleobase Lesion DNA N-glycosylase Activity Enzyme Binding Protein Kinase Binding Poly(A) RNA Binding Protein Kinase A Binding NF-kappaB Binding Iron-sulfur Cluster Binding
	Biological Process	DNA Repair Protein Sumoylation Cytokine-mediated Signaling Pathway PML Body Organization Positive Regulation Of Protein Complex Assembly Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Localization Negative Regulation Of DNA Binding Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Post-translational Protein Modification Cellular Protein Metabolic Process Negative Regulation Of Transcription, DNA-templated Palate Development Interferon-gamma-mediated Signaling Pathway Regulation Of Interferon-gamma-mediated Signaling Pathway Protein Localization To Nuclear Pore	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay DNA Catabolic Process, Endonucleolytic Cytoplasmic Translation DNA Repair Transcription, DNA-templated Translation Translational Initiation Translational Elongation Translational Termination Regulation Of Translation SRP-dependent Cotranslational Protein Targeting To Membrane Apoptotic Process Cellular Response To DNA Damage Stimulus Mitotic Nuclear Division Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process Negative Regulation Of DNA Repair Positive Regulation Of NF-kappaB Transcription Factor Activity Cell Division Positive Regulation Of DNA N-glycosylase Activity Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Interferon gamma signaling SUMO is proteolytically processed Post-translational protein modification SUMOylation Interferon Signaling Cytokine Signaling in Immune system SUMO is conjugated to E1 (UBA2:SAE1) Regulation of IFNG signaling SUMO is transferred from E1 to E2 (UBE2I, UBC9) Processing and activation of SUMO	Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		194 interactors: ADD3 APP AR ARL13A ATF2 ATF3 ATXN1 ATXN3 ATXN7 AURKA AURKB BCAM BCL11A BIRC3 BLM BRCA1 C11orf65 C18orf25 CAMSAP2 CARD9 CASP2 CASP8 CCDC67 CD40 CDCA8 CHAF1A CHD3 CHD4 COG1 CTNNA1 DAXX DDX24 DNM1 DNMT3A DNMT3B DTX2 EDARADD ESR1 ETV1 ETV4 ETV6 FADD FAM118B FANCM FAS FASLG FBF1 FLI1 FOS FOXL2 FOXM1 GATA1 GLP1R GMCL1 HDAC4 HDAC9 HGS HIF1A HIPK2 HIPK3 HIRA HNF4A HNRNPC HNRNPK HSF1 HSF2 HTT ING2 IRAK1 JUN KAT2A KAT6B KDM1A KRT14 KRT18 KRT5 KRT8 MAP2K1 MAPK1IP1L MDC1 MDM2 MECOM MEF2A MEF2C MITF MKL1 MSX1 MUL1 MX1 MYB NCOA1 NCOA2 NCOA3 NCOR2 NELFE NFE2L2 NFKBIA NIN NOS1 NOX5 NR3C1 NR3C2 PARK7 PARP1 PAX6 PDGFC PHC1 PIAS1 PIAS2 PIAS3 PIAS4 PIK3C3 PLK3 PML PPARA PPM1J RAD51 RAD52 RAD54B RAD54L2 RANBP2 RANGAP1 RB1 RBM25 RHOXF2 RNF4 RPS3 SAE1 SALL1 SART1 SATB1 SEMA6A SENP1 SENP2 SENP6 SETX SH3KBP1 SLC2A1 SOX10 SOX2 SOX6 SP1 SP100 SP3 SREBF1 SREBF2 SSRP1 STAB2 STK24 STMN2 SUMO1P1 SUMO2 SUPT7L SYMPK TCERG1 TCF4 TDG TDP2 TFCP2 TGM2 TNFRSF1A TOE1 TOP1 TOP2A TOP2B TOPORS TP53 TP73 TRAF4 TRIM24 TRIM5 TRPS1 TSC22D3 TSHZ2 TSNAX UBA2 UBE2I USP25 USP7 USPL1 WNK1 WRN XRCC1 XRCC5 ZBTB16 ZBTB26 ZBTB6 ZBTB7A ZCCHC12 ZCCHC7 ZMYM2 ZMYM5 ZNF24 ZNF451	14 interactors: ATP6V0D2 CCT2 CSNK2A1 FOLH1 HSP90AA1 IL7R MDM2 NDRG1 NFKB1 RELA RPL9 SUMO1 TP53 YWHAQ
Entrez ID		7341	6188
HPRD ID		03554	10941
Ensembl ID		ENSG00000116030	ENSG00000149273
Uniprot IDs		P63165	P23396
PDB IDs		1A5R 1TGZ 1WYW 1Y8R 1Z5S 2ASQ 2BF8 2G4D 2IO2 2IY0 2IY1 2KQS 2LAS 2PE6 2UYZ 2VRR 3KYC 3KYD 3RZW 3UIP	1WH9 3J3A
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Macromolecule Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Cell Death Regulation Of Apoptotic Process Biosynthetic Process Cellular Metabolic Process Regulation Of Cellular Process Organelle Organization Chromosome Organization Cellular Response To Organic Substance Protein Sumoylation Cellular Response To Stimulus Response To Organic Substance Response To Stimulus Developmental Process Programmed Cell Death Apoptotic Process Peptidyl-lysine Modification	Cellular Response To Alkaloid Immune Response Positive Regulation Of MiRNA Metabolic Process Membrane Organization Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Protein Localization To Organelle Immune System Process Cellular Response To Nicotine Signal Transduction DNA Damage Response, Signal Transduction By P53 Class Mediator Cell Surface Receptor Signaling Pathway Fc Receptor Signaling Pathway Regulation Of MiRNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Response To Abiotic Stimulus Signal Transduction In Response To DNA Damage Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Signaling Cellular Response To Hypoxia Cellular Response To Peptide Hormone Stimulus Response To Organic Substance Cellular Response To Decreased Oxygen Levels Chaperone-mediated Protein Complex Assembly Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Communication Cellular Response To Peptide Cellular Response To Oxygen Levels Signal Transduction By P53 Class Mediator Cellular Response To Organic Substance Protein Localization Membrane Protein Intracellular Domain Proteolysis Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Immune System Process Negative Regulation Of Gene Expression Response To UV Regulation Of Protein Catabolic Process Negative Regulation Of Biosynthetic Process Cellular Protein Localization Innate Immune Response Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Response To Alkaloid Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Response To Oxidative Stress Protein Targeting Regulation Of Apoptotic Process
Tagcloud ?		aphidicolin attachment break breakage budding cfs covalent excessive fields fragile hallmark modifier ortholog perturbed pol32 pold3 polypeptides proteomic recombinational replication resource rpa ssdna stresses subfamily sumo2 sumo3 sumoylation	apocytochrome infa l20 l22 l33 liverwort marchantia peta petb petd preprotein psbb psbe psbf psbh rpl14 rpl16 rpl2 rpl20 rpl22 rpl23 rpl33 rpoa rps11 rps12 rps18 rps8 secx ugg
Tagcloud (Difference) ?		aphidicolin attachment break breakage budding cfs covalent excessive fields fragile hallmark modifier ortholog perturbed pol32 pold3 polypeptides proteomic recombinational replication resource rpa ssdna stresses subfamily sumo2 sumo3 sumoylation	apocytochrome infa l20 l22 l33 liverwort marchantia peta petb petd preprotein psbb psbe psbf psbh rpl14 rpl16 rpl2 rpl20 rpl22 rpl23 rpl33 rpoa rps11 rps12 rps18 rps8 secx ugg
Tagcloud (Intersection) ?