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SUMO1 and RPS3
Number of citations of the paper that reports this interaction (PubMedID
21968017
)
0
Data Source:
BioGRID
(pull down)
SUMO1
RPS3
Description
small ubiquitin like modifier 1
ribosomal protein S3
Image
GO Annotations
Cellular Component
XY Body
Nucleus
Nuclear Pore
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Plasma Membrane
Voltage-gated Potassium Channel Complex
Membrane
Nuclear Body
PML Body
Nuclear Speck
Nuclear Membrane
Nuclear Stress Granule
Glutamatergic Synapse
Presynaptic Cytosol
Postsynaptic Cytosol
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Matrix
Endoplasmic Reticulum
Spindle
Cytosol
Ribosome
Cytoskeleton
Plasma Membrane
Focal Adhesion
Postsynaptic Density
Small Ribosomal Subunit
Membrane
Cytosolic Ribosome
Cytosolic Small Ribosomal Subunit
Ruffle Membrane
Synapse
Extracellular Exosome
NF-kappaB Complex
Mitotic Spindle
Ribonucleoprotein Complex
Molecular Function
RNA Binding
Protein Binding
Transcription Factor Binding
Potassium Channel Regulator Activity
Enzyme Binding
Protein Tag Activity
Ubiquitin Protein Ligase Binding
Small Protein Activating Enzyme Binding
Ubiquitin-like Protein Ligase Binding
Transporter Activator Activity
Ubiquitin-specific Protease Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA Binding
Damaged DNA Binding
RNA Binding
MRNA Binding
Structural Constituent Of Ribosome
DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity
DNA Endonuclease Activity
Protein Binding
Microtubule Binding
Tubulin Binding
Lyase Activity
DNA N-glycosylase Activity
Enzyme Binding
Kinase Binding
Protein Kinase Binding
Hsp70 Protein Binding
Oxidized Purine DNA Binding
Oxidized Pyrimidine DNA Binding
Ubiquitin-like Protein Conjugating Enzyme Binding
Protein-containing Complex Binding
Protein Kinase A Binding
Iron-sulfur Cluster Binding
Hsp90 Protein Binding
Small Ribosomal Subunit RRNA Binding
Supercoiled DNA Binding
Class I DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity
DNA-binding Transcription Factor Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
DNA Repair
Regulation Of DNA-templated Transcription
Protein Sumoylation
PML Body Organization
Positive Regulation Of Protein-containing Complex Assembly
Regulation Of Protein Stability
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Localization
Cellular Response To Heat
Negative Regulation Of Protein Import Into Nucleus
Negative Regulation Of DNA Binding
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of Action Potential
Negative Regulation Of DNA-templated Transcription
Protein Stabilization
Roof Of Mouth Development
Cellular Response To Cadmium Ion
Regulation Of Cardiac Muscle Cell Contraction
Protein Localization To Nuclear Pore
Negative Regulation Of Potassium Ion Transmembrane Transporter Activity
Negative Regulation Of Delayed Rectifier Potassium Channel Activity
Regulation Of Calcium Ion Transmembrane Transport
Cytoplasmic Translation
DNA Repair
Base-excision Repair
Translation
Translational Initiation
Regulation Of Translation
Apoptotic Process
DNA Damage Response
Chromosome Segregation
Positive Regulation Of Gene Expression
Negative Regulation Of Translation
Positive Regulation Of Microtubule Polymerization
Positive Regulation Of Protein-containing Complex Assembly
Negative Regulation Of Protein Ubiquitination
Positive Regulation Of Endodeoxyribonuclease Activity
Positive Regulation Of Interleukin-2 Production
Cellular Response To Reactive Oxygen Species
Positive Regulation Of Activated T Cell Proliferation
Regulation Of Apoptotic Process
Negative Regulation Of DNA Repair
Positive Regulation Of DNA Repair
Positive Regulation Of T Cell Receptor Signaling Pathway
Positive Regulation Of NF-kappaB Transcription Factor Activity
Spindle Assembly
Cell Division
Response To TNF Agonist
Cellular Response To Hydrogen Peroxide
Cellular Response To Tumor Necrosis Factor
Positive Regulation Of Non-canonical NF-kappaB Signal Transduction
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Positive Regulation Of Base-excision Repair
Positive Regulation Of Apoptotic Signaling Pathway
Pathways
SUMO is conjugated to E1 (UBA2:SAE1)
SUMO is transferred from E1 to E2 (UBE2I, UBC9)
SUMO is proteolytically processed
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription factors
SUMOylation of transcription factors
SUMOylation of ubiquitinylation proteins
SUMOylation of transcription cofactors
SUMOylation of transcription cofactors
SUMOylation of SUMOylation proteins
SUMOylation of intracellular receptors
SUMOylation of intracellular receptors
SUMOylation of chromatin organization proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA methylation proteins
SUMOylation of DNA methylation proteins
SUMOylation of immune response proteins
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Formation of Incision Complex in GG-NER
Regulation of IFNG signaling
Negative regulation of activity of TFAP2 (AP-2) family transcription factors
Negative regulation of activity of TFAP2 (AP-2) family transcription factors
Postmitotic nuclear pore complex (NPC) reformation
Maturation of nucleoprotein
Maturation of nucleoprotein
SUMOylation of nuclear envelope proteins
PKR-mediated signaling
Transcriptional and post-translational regulation of MITF-M expression and activity
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
SARS-CoV-1 modulates host translation machinery
SARS-CoV-2 modulates host translation machinery
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Diseases
GWAS
Interacting Genes
154 interacting genes:
AR
ARK2N
ARRB2
ATF2
ATXN1
ATXN3
ATXN7
AXIN1
BIRC3
BLM
BRCA1
BTBD3
C11orf65
CANX
CARD9
CASP2
CASP8
CCR2
CDK6
CEBPA
CHAF1A
CHD3
CREBBP
DAXX
DEUP1
DNM1
DNMT3B
DTX2
EDARADD
EGLN3
EIF2AK2
ERCC6
ETV6
FAF1
FAM118B
FAS
FASLG
FBF1
FOS
FOXM1
GMCL1
HDAC4
HDAC9
HGS
HIF1A
HIPK2
HIPK3
HNRNPC
HNRNPK
HSF1
HTT
IKZF3
IRAK1
ISG15
JUN
MAPK1IP1L
MDM2
MEF2A
MITF
MRE11
MRTFA
MSX1
MTOR
MUL1
MYB
NCOA1
NCOA2
NCOA3
NCOR2
NFE2L2
NFKBIA
NIN
NR3C1
NR3C2
PARK7
PAX6
PCNA
PDGFC
PHC1
PIAS1
PIAS2
PIAS3
PIAS4
PKM
PLAGL1
PML
PPM1J
PRKN
PROP1
PSIP1
RAD51
RAD52
RAD54B
RAD54L2
RANBP2
RANGAP1
RHOXF2
RNF111
RNF167
RNF4
RPS3
SALL1
SATB1
SENP1
SENP2
SENP6
SETX
SLC2A1
SMARCAD1
SOX10
SOX2
SOX6
SP100
SP3
SPOP
SREBF1
SREBF2
SUMO1P1
TDG
TDP2
TFCP2
TMIE
TNFRSF1A
TOE1
TOP1
TOP2A
TOP2B
TOPORS
TP53
TP73
TRAF2
TRAF4
TRAF5
TRIM24
TRPS1
TSC22D3
UBA2
UBE2I
USP25
USPL1
WRN
ZBED1
ZBTB16
ZBTB2
ZBTB26
ZBTB6
ZCCHC12
ZCCHC7
ZFP42
ZHX1
ZMYM2
ZMYM3
ZMYM5
ZNF451
28 interacting genes:
ATP6V0D2
CCT2
CDK1
CDK2
CSNK2A1
DDIT3
DUX4
FNDC3B
FOLH1
FOXP1
HSP90AA1
IL7R
MDM2
NDRG1
NFKB1
OGT
PTEN
RELA
RNF10
RPL9
SUMO1
SUMO2
UBC
UBXN7
USP7
WBP2
YWHAQ
ZNF598
Entrez ID
7341
6188
HPRD ID
03554
10941
Ensembl ID
ENSG00000116030
ENSG00000149273
Uniprot IDs
B8ZZN6
B9A032
P63165
P23396
PDB IDs
1A5R
1TGZ
1WYW
1Y8R
1Z5S
2ASQ
2BF8
2G4D
2IO2
2IY0
2IY1
2KQS
2LAS
2MW5
2N1A
2N1V
2PE6
2UYZ
2VRR
3KYC
3KYD
3RZW
3UIP
4WJN
4WJO
4WJP
4WJQ
5AEK
5B7A
5ELJ
5GHD
6EOP
6EOT
6J4I
6JXU
6JXV
6K5T
6TRW
6UYO
6UYP
6UYQ
6UYR
6UYS
6UYT
6UYU
6UYV
6UYX
6UYY
6UYZ
6V7P
6V7Q
6V7R
6V7S
6WW3
6XOG
6XOH
6XOI
8DJH
8DJI
8ODR
9B62
1WH9
4UG0
4V6X
5A2Q
5AJ0
5FLX
5LKS
5OA3
5T2C
5VYC
6FEC
6G51
6G53
6G5H
6G5I
6IP5
6IP6
6IP8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6XA1
6Y0G
6Y2L
6Y57
6YBS
6Z6L
6Z6M
6Z6N
6ZLW
6ZM7
6ZME
6ZMI
6ZMO
6ZMT
6ZMW
6ZN5
6ZOJ
6ZOL
6ZON
6ZP4
6ZUO
6ZV6
6ZVH
6ZVJ
6ZXD
6ZXE
6ZXF
6ZXG
6ZXH
7A09
7K5I
7QP6
7QP7
7QVP
7R4X
7TQL
7XNX
7XNY
8G5Y
8G5Z
8G60
8G61
8G6J
8GLP
8IFD
8IFE
8JDJ
8JDK
8JDL
8JDM
8K2C
8OZ0
8PJ1
8PJ2
8PJ3
8PJ4
8PJ5
8PJ6
8PPK
8PPL
8QOI
8T4S
8UKB
8XP2
8XP3
8XSX
8XSY
8XSZ
8XXL
8XXM
8XXN
8Y0W
8Y0X
8YOO
8YOP
8ZDB
8ZDC
8ZDD
9BKD
9BLN
9C3H
9G8M
9G8O
Enriched GO Terms of Interacting Partners
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Regulation Of RNA Biosynthetic Process
Regulation Of DNA-templated Transcription
Regulation Of Primary Metabolic Process
Nucleus
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Metabolic Process
PML Body
Nucleoplasm
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
Negative Regulation Of RNA Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Biosynthetic Process
Negative Regulation Of Metabolic Process
DNA Binding
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of RNA Biosynthetic Process
Protein Sumoylation
Positive Regulation Of DNA-templated Transcription
Cellular Response To Stress
Positive Regulation Of RNA Metabolic Process
Chromatin
Positive Regulation Of Transcription By RNA Polymerase II
SUMO Transferase Activity
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Chromatin Binding
DNA Damage Response
Regulation Of Apoptotic Process
Regulation Of Programmed Cell Death
Protein Modification By Small Protein Conjugation
Post-translational Protein Modification
Macromolecule Metabolic Process
Response To Stress
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Nuclear Body
Protein-containing Complex
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Protein Catabolic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Ubiquitin Protein Ligase Binding
Regulation Of Proteasomal Protein Catabolic Process
Protein Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Biosynthetic Process
Cytosol
Regulation Of Proteolysis
Regulation Of Primary Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Intracellular Signal Transduction
Regulation Of Transcription By RNA Polymerase II
Regulation Of Gene Expression
Regulation Of RNA Metabolic Process
PML Body
Regulation Of Metabolic Process
Regulation Of Macromolecule Metabolic Process
Protein Tag Activity
Regulation Of Protein Stability
Protein Stabilization
NF-kappaB P50/p65 Complex
DNA Damage Response
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Nucleus
Negative Regulation Of Biosynthetic Process
Signal Transduction In Response To DNA Damage
Macromolecule Metabolic Process
Protein Catabolic Process
Post-translational Protein Modification
Nucleoplasm
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Cyclin-dependent Protein Kinase Activity
Symbiont-mediated Disruption Of Host Cell PML Body
Negative Regulation Of Gene Expression
Apoptotic Process
Negative Regulation Of Metabolic Process
Regulation Of DNA Metabolic Process
Programmed Cell Death
Regulation Of Schwann Cell Differentiation
Cell Death
Positive Regulation Of Gene Expression
Regulation Of Protein Metabolic Process
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