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UBE2G1 and HUWE1
Number of citations of the paper that reports this interaction (PMID
22016339
)
8
Data Source:
BioGRID
(pull down)
UBE2G1
HUWE1
Gene Name
ubiquitin-conjugating enzyme E2G 1
HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Extracellular Vesicular Exosome
Nucleus
Nucleoplasm
Cytoplasm
Membrane
Extracellular Vesicular Exosome
Molecular Function
Ubiquitin-protein Transferase Activity
ATP Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Protein Ligase Activity
Ubiquitin Conjugating Enzyme Activity
DNA Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Ligase Activity
Poly(A) RNA Binding
Biological Process
Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Catabolic Process
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein Polyubiquitination
Base-excision Repair
Protein Monoubiquitination
Histone Ubiquitination
Cell Differentiation
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
13 interactors:
AMFR
APP
CBL
DIO2
HUWE1
ITCH
MARCH6
PARK2
RBCK1
RBX1
UBA1
UBE2E1
UBE3A
20 interactors:
ABL1
CALM1
CCL1
CDKN2A
HDAC2
LAPTM5
MCL1
MYC
PIAS2
POLB
RNF11
SMAD2
SMAD9
TP53
UBE2D1
UBE2D2
UBE2D3
UBE2G1
UBE2L3
USP4
Entrez ID
7326
10075
HPRD ID
03340
06608
Ensembl ID
ENSG00000132388
ENSG00000086758
Uniprot IDs
P62253
Q7Z6Z7
PDB IDs
2AWF
2EKK
3G1N
3H1D
Enriched GO Terms of Interacting Partners
?
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Polyubiquitination
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Protein K48-linked Ubiquitination
Ubiquitin-dependent Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Cellular Protein Metabolic Process
Cellular Protein Modification Process
Catabolic Process
Protein Monoubiquitination
Protein Metabolic Process
Proteolysis
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Protein K29-linked Ubiquitination
Cellular Metabolic Process
Cellular Response To Stimulus
Regulation Of Protein Catabolic Process
Notch Signaling Pathway
Negative Regulation Of JNK Cascade
Protein K63-linked Ubiquitination
Intracellular Receptor Signaling Pathway
Viral Process
Regulation Of Protein Ubiquitination
Negative Regulation Of Stress-activated MAPK Cascade
Histone Ubiquitination
Positive Regulation Of Protein Catabolic Process
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Protein Autoubiquitination
Regulation Of Signal Transduction
Response To Stimulus
Regulation Of Cellular Protein Metabolic Process
Regulation Of Proteolysis
Learning Or Memory
Cognition
Positive Regulation Of Proteolysis
Regulation Of Signaling
Negative Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Protein Metabolic Process
Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Sperm Entry
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Mitochondrial Fusion
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Signaling
Transforming Growth Factor Beta Receptor Signaling Pathway
Protein Polyubiquitination
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Enzyme Linked Receptor Protein Signaling Pathway
Protein Modification By Small Protein Conjugation
Protein K48-linked Ubiquitination
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Cellular Response To Stress
Response To Organic Substance
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Cellular Protein Modification Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Ubiquitination
Protein Catabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Protein Ubiquitination
Signal Transduction
Cellular Response To Organic Substance
Regulation Of Ubiquitin-protein Transferase Activity
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Negative Regulation Of Cell Cycle
Cellular Response To Hypoxia
Response To Abiotic Stimulus
Cellular Response To Decreased Oxygen Levels
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Protein Ubiquitination
Positive Regulation Of Cellular Protein Metabolic Process
Cellular Response To Stimulus
Signaling
Cellular Response To Oxygen Levels
Negative Regulation Of Cellular Metabolic Process
Cell Communication
Response To Stress
Positive Regulation Of Protein Metabolic Process
Regulation Of Response To DNA Damage Stimulus
Response To Hypoxia
Cellular Macromolecule Catabolic Process
Transcription, DNA-templated
Cellular Protein Metabolic Process
Cell Cycle Arrest
Catabolic Process
Regulation Of Cell Cycle
RNA Biosynthetic Process
Intracellular Signal Transduction
Tagcloud
?
attractive
bicyclic
biol
catalyze
chem
cys
displacement
druggable
e2
e3
freund
heclin
hect
heinis
hek293
huge
kills
ligase
ligases
makes
mule
nat
phage
proven
rutherford
smurf2
thioesters
winter
wwp1
Tagcloud (Difference)
?
attractive
bicyclic
biol
catalyze
chem
cys
displacement
druggable
e2
e3
freund
heclin
hect
heinis
hek293
huge
kills
ligase
ligases
makes
mule
nat
phage
proven
rutherford
smurf2
thioesters
winter
wwp1
Tagcloud (Intersection)
?