UBE2G1 and AMFR

Number of citations of the paper that reports this interaction (PMID 12847084)
143

Data Source:
BioGRID (pull down, x-ray crystallography, pull down, pull down, pull down)

		UBE2G1	AMFR
Gene Name		ubiquitin-conjugating enzyme E2G 1	autocrine motility factor receptor, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Extracellular Vesicular Exosome	Hrd1p Ubiquitin Ligase Complex Nucleus Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Dendrite Growth Cone Neuronal Cell Body Protein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity Ubiquitin Conjugating Enzyme Activity	Ubiquitin-protein Transferase Activity Receptor Activity Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Cellular Protein Catabolic Process Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Movement Of Cell Or Subcellular Component Signal Transduction Aging Learning Or Memory ER-associated Ubiquitin-dependent Protein Catabolic Process Endoplasmic Reticulum Unfolded Protein Response Protein Oligomerization
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: AMFR APP CBL DIO2 HUWE1 ITCH MARCH6 PARK2 RBCK1 RBX1 UBA1 UBE2E1 UBE3A	26 interactors: BAG6 CRMP1 CYP2E1 CYP3A4 DERL1 DHFR GPI HERPUD1 HTT KPNB1 SOD1 SYVN1 TOM1L1 TRIM25 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2G1 UBE2G2 UBE2K UBE2N UBE2T UBE2W UFD1L VCP
Entrez ID		7326	267
HPRD ID		03340	09130
Ensembl ID		ENSG00000132388	ENSG00000159461
Uniprot IDs		P62253	Q9UKV5
PDB IDs		2AWF	2EJS 2LVN 2LVO 2LVP 2LVQ 2LXH 2LXP 3FSH 3H8K 3TIW 4G3O
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Polyubiquitination Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Protein K48-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Cellular Protein Metabolic Process Cellular Protein Modification Process Catabolic Process Protein Monoubiquitination Protein Metabolic Process Proteolysis Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein K29-linked Ubiquitination Cellular Metabolic Process Cellular Response To Stimulus Regulation Of Protein Catabolic Process Notch Signaling Pathway Negative Regulation Of JNK Cascade Protein K63-linked Ubiquitination Intracellular Receptor Signaling Pathway Viral Process Regulation Of Protein Ubiquitination Negative Regulation Of Stress-activated MAPK Cascade Histone Ubiquitination Positive Regulation Of Protein Catabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Protein Autoubiquitination Regulation Of Signal Transduction Response To Stimulus Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Learning Or Memory Cognition Positive Regulation Of Proteolysis Regulation Of Signaling Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Protein Metabolic Process Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Sperm Entry Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Signaling	Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Catabolic Process Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K48-linked Ubiquitination Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteolysis Proteasomal Protein Catabolic Process Cellular Metabolic Process Cellular Response To Stress Protein K11-linked Ubiquitination Cellular Protein Metabolic Process Response To Endoplasmic Reticulum Stress Response To Stress Protein K63-linked Ubiquitination Response To Organic Substance ER-associated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Topologically Incorrect Protein Cellular Response To Organic Substance Response To Stimulus Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Metabolic Process Protein Metabolic Process Cellular Protein Modification Process Toll-like Receptor 4 Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Apoptotic Process Toll-like Receptor Signaling Pathway Programmed Cell Death Cell Death Death Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Retrograde Protein Transport, ER To Cytosol Response To Unfolded Protein Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Protein Monoubiquitination Monoterpenoid Metabolic Process
Tagcloud ?			anchoring catalyzed dnas e3 eris facilitating herpes hsv insig1 interacted k27 ligase microbial microsomes missing mita mpys perinuclear platform polyubiquitination recruiting revealing served simplex stimulator sting tank tbk1 uncovers
Tagcloud (Difference) ?			anchoring catalyzed dnas e3 eris facilitating herpes hsv insig1 interacted k27 ligase microbial microsomes missing mita mpys perinuclear platform polyubiquitination recruiting revealing served simplex stimulator sting tank tbk1 uncovers
Tagcloud (Intersection) ?