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UBA1 and UBE2G1
Number of citations of the paper that reports this interaction (PMID
17597759
)
66
Data Source:
BioGRID
(pull down)
UBA1
UBE2G1
Gene Name
ubiquitin-like modifier activating enzyme 1
ubiquitin-conjugating enzyme E2G 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Heterochromatin
Nucleus
Cytoplasm
Mitochondrion
Lysosomal Membrane
Cytosol
Endosome Membrane
Desmosome
Rough Endoplasmic Reticulum Membrane
Extracellular Vesicular Exosome
Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
Ubiquitin Activating Enzyme Activity
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Poly(A) RNA Binding
Ubiquitin-protein Transferase Activity
ATP Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Protein Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Biological Process
Cellular Response To DNA Damage Stimulus
Protein Ubiquitination
Modification-dependent Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Catabolic Process
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
39 interactors:
BUB3
CDC34
CDK1
CREB3L1
CREB3L2
ECHS1
GAN
GRB2
HGS
HSPH1
MGMT
PIAS3
SEMA3F
SMAD5
TAF9
TMCC2
TSSC4
TTC19
UBC
UBE2A
UBE2B
UBE2C
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2E2
UBE2E3
UBE2G1
UBE2G2
UBE2H
UBE2J1
UBE2K
UBE2L3
UBE2R2
UBE2S
UBE2T
UBE2W
UBTD2
13 interactors:
AMFR
APP
CBL
DIO2
HUWE1
ITCH
MARCH6
PARK2
RBCK1
RBX1
UBA1
UBE2E1
UBE3A
Entrez ID
7317
7326
HPRD ID
02440
03340
Ensembl ID
ENSG00000130985
ENSG00000132388
Uniprot IDs
P22314
P62253
PDB IDs
2AWF
Enriched GO Terms of Interacting Partners
?
Protein K48-linked Ubiquitination
Protein Polyubiquitination
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Protein K11-linked Ubiquitination
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Cellular Protein Modification Process
Proteolysis
Catabolic Process
Cellular Protein Metabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Protein Metabolic Process
Protein K63-linked Ubiquitination
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Protein Monoubiquitination
Cellular Response To Stress
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Regulation Of Protein Ubiquitination
Cellular Metabolic Process
Positive Regulation Of Protein Ubiquitination
Regulation Of Protein Catabolic Process
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Cellular Response To DNA Damage Stimulus
Response To Organic Substance
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
TRIF-dependent Toll-like Receptor Signaling Pathway
Negative Regulation Of Ubiquitin-protein Transferase Activity
Negative Regulation Of Proteasomal Protein Catabolic Process
MyD88-independent Toll-like Receptor Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Toll-like Receptor 3 Signaling Pathway
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Cellular Protein Catabolic Process
Toll-like Receptor 4 Signaling Pathway
Mitotic Cell Cycle Checkpoint
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Cell Cycle Process
Mitotic Spindle Assembly Checkpoint
Negative Regulation Of Chromosome Organization
Spindle Assembly Checkpoint
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Polyubiquitination
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Protein K48-linked Ubiquitination
Ubiquitin-dependent Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Cellular Protein Metabolic Process
Cellular Protein Modification Process
Catabolic Process
Protein Monoubiquitination
Protein Metabolic Process
Proteolysis
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Protein K29-linked Ubiquitination
Cellular Metabolic Process
Cellular Response To Stimulus
Regulation Of Protein Catabolic Process
Notch Signaling Pathway
Negative Regulation Of JNK Cascade
Protein K63-linked Ubiquitination
Intracellular Receptor Signaling Pathway
Viral Process
Regulation Of Protein Ubiquitination
Negative Regulation Of Stress-activated MAPK Cascade
Histone Ubiquitination
Positive Regulation Of Protein Catabolic Process
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Protein Autoubiquitination
Regulation Of Signal Transduction
Response To Stimulus
Regulation Of Cellular Protein Metabolic Process
Regulation Of Proteolysis
Learning Or Memory
Cognition
Positive Regulation Of Proteolysis
Regulation Of Signaling
Negative Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Protein Metabolic Process
Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Sperm Entry
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Mitochondrial Fusion
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Signaling
Tagcloud
?
aspect
bax
box
caspases
consisting
counterpart
debcl
degrading
documented
drosophila
e3
fruitfly
homologue
iaps
identifies
involve
ligase
modifier
multimeric
proteasome
proteolytic
regulators
scf
screen
shed
slimb
stimulates
trcp
ubiquitin
Tagcloud (Difference)
?
aspect
bax
box
caspases
consisting
counterpart
debcl
degrading
documented
drosophila
e3
fruitfly
homologue
iaps
identifies
involve
ligase
modifier
multimeric
proteasome
proteolytic
regulators
scf
screen
shed
slimb
stimulates
trcp
ubiquitin
Tagcloud (Intersection)
?