UBA1 and SEMA3F

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		UBA1	SEMA3F
Gene Name		ubiquitin-like modifier activating enzyme 1	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Heterochromatin Nucleus Cytoplasm Mitochondrion Lysosomal Membrane Cytosol Endosome Membrane Desmosome Rough Endoplasmic Reticulum Membrane Extracellular Vesicular Exosome	Extracellular Space Membrane
	Molecular Function	Ubiquitin Activating Enzyme Activity Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Poly(A) RNA Binding	Receptor Activity Chemorepellent Activity
	Biological Process	Cellular Response To DNA Damage Stimulus Protein Ubiquitination Modification-dependent Protein Catabolic Process	Axon Guidance Facial Nerve Structural Organization Trigeminal Nerve Structural Organization Nerve Development Branchiomotor Neuron Axon Guidance Ventral Trunk Neural Crest Cell Migration Negative Regulation Of Axon Extension Involved In Axon Guidance Axon Extension Involved In Axon Guidance Negative Chemotaxis Sympathetic Ganglion Development Sympathetic Neuron Projection Extension Sympathetic Neuron Projection Guidance Neural Crest Cell Migration Involved In Autonomic Nervous System Development Semaphorin-plexin Signaling Pathway Involved In Neuron Projection Guidance Semaphorin-plexin Signaling Pathway Involved In Axon Guidance
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		39 interactors: BUB3 CDC34 CDK1 CREB3L1 CREB3L2 ECHS1 GAN GRB2 HGS HSPH1 MGMT PIAS3 SEMA3F SMAD5 TAF9 TMCC2 TSSC4 TTC19 UBC UBE2A UBE2B UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2G1 UBE2G2 UBE2H UBE2J1 UBE2K UBE2L3 UBE2R2 UBE2S UBE2T UBE2W UBTD2	6 interactors: NRP1 NRP2 SHBG SLC35G2 UBA1 VEGFA
Entrez ID		7317	6405
HPRD ID		02440	03079
Ensembl ID		ENSG00000130985	ENSG00000001617
Uniprot IDs		P22314	Q13275
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein K11-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Cellular Protein Modification Process Proteolysis Catabolic Process Cellular Protein Metabolic Process Regulation Of Ubiquitin-protein Transferase Activity Protein Metabolic Process Protein K63-linked Ubiquitination Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Protein Monoubiquitination Cellular Response To Stress Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Protein Ubiquitination Cellular Metabolic Process Positive Regulation Of Protein Ubiquitination Regulation Of Protein Catabolic Process Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Cellular Response To DNA Damage Stimulus Response To Organic Substance Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Proteasomal Protein Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Toll-like Receptor 3 Signaling Pathway Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Toll-like Receptor 4 Signaling Pathway Mitotic Cell Cycle Checkpoint Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cell Cycle Process Mitotic Spindle Assembly Checkpoint Negative Regulation Of Chromosome Organization Spindle Assembly Checkpoint	Vascular Endothelial Growth Factor Signaling Pathway Cellular Response To Vascular Endothelial Growth Factor Stimulus Vestibulocochlear Nerve Structural Organization Positive Regulation Of Retinal Ganglion Cell Axon Guidance VEGF-activated Neuropilin Signaling Pathway Ganglion Morphogenesis Sensory Neuron Axon Guidance Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Endothelial Cell Proliferation Regulation Of Retinal Ganglion Cell Axon Guidance Facioacoustic Ganglion Development Gonadotrophin-releasing Hormone Neuronal Migration To The Hypothalamus Positive Regulation Of Epithelial Cell Migration Developmental Cell Growth Coronary Artery Morphogenesis Sympathetic Neuron Projection Extension Sympathetic Neuron Projection Guidance Ventral Trunk Neural Crest Cell Migration Regulation Of Endothelial Cell Proliferation Vascular Endothelial Growth Factor Receptor Signaling Pathway Hypothalamus Cell Migration Neural Crest Cell Migration Involved In Autonomic Nervous System Development Trigeminal Ganglion Development Endothelial Cell Chemotaxis Positive Regulation Of Axon Extension Involved In Axon Guidance Semaphorin-plexin Signaling Pathway Involved In Neuron Projection Guidance Regulation Of Endothelial Cell Migration Growth Hypothalamus Cell Differentiation Vestibulocochlear Nerve Development Axon Extension Involved In Axon Guidance Sympathetic Ganglion Development Coronary Vasculature Morphogenesis Facial Nerve Structural Organization Facial Nerve Morphogenesis Regulation Of Epithelial Cell Migration Cell Growth Cerebral Cortex Tangential Migration Positive Regulation Of Epithelial Cell Proliferation Commissural Neuron Axon Guidance Coronary Vasculature Development Ganglion Development Ameboidal-type Cell Migration Regulation Of Axon Extension Involved In Axon Guidance Parasympathetic Nervous System Development Anatomical Structure Arrangement Cell Migration Involved In Sprouting Angiogenesis Sympathetic Nervous System Development Hypothalamus Development Positive Chemotaxis
Tagcloud ?		aspect bax box caspases consisting counterpart debcl degrading documented drosophila e3 fruitfly homologue iaps identifies involve ligase modifier multimeric proteasome proteolytic regulators scf screen shed slimb stimulates trcp ubiquitin
Tagcloud (Difference) ?		aspect bax box caspases consisting counterpart debcl degrading documented drosophila e3 fruitfly homologue iaps identifies involve ligase modifier multimeric proteasome proteolytic regulators scf screen shed slimb stimulates trcp ubiquitin
Tagcloud (Intersection) ?