TYK2 and EIF2AK2

  • Number of citations of the paper that reports this interaction (PMID 17290288)
  • 8
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)
  • HPRD (in vivo)

TYK2

EIF2AK2

Gene Name tyrosine kinase 2 eukaryotic translation initiation factor 2-alpha kinase 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 36 interactors: CBL COPS5 CRKL DNM2 EIF2AK2 FHL3 FYN GHR GNB2L1 HNRNPK IFNAR1 IFNAR2 IL13RA1 IL6ST IRS1 IRS2 JAK1 JAKMIP1 KHDRBS2 KRT40 LYN PDGFRB PIK3R1 PLAUR PRMT5 PTAFR PTPN1 PTPN6 PTPRC STAM2 STAT1 STAT2 TK1 TRAF4 VAV1 XRCC5 48 interactors: CASP3 CASP7 CASP8 CDC42 CHUK DHX30 DHX58 DHX9 DICER1 DNAJC3 EDC4 EIF2S1 EIF6 ELF2 FTSJ3 HIST2H2AC HSP90AA1 HSPA1A IKBKB IL7R ILF2 ILF3 JAK1 MAP3K5 MAP3K7 METAP2 MOV10 NFKBIA NPM1 PDGFRB PPP1CA PPP1CC PPP2R5A PRKRA PRKRIP1 PRKRIR PTGES3 RAC1 STAT1 STAT3 STRBP TAB2 TARBP2 TIRAP TOLLIP TP53 TYK2 ZNF346
Entrez ID 7297 5610
HPRD ID 01490 01468
Ensembl ID ENSG00000105397 ENSG00000055332
Uniprot IDs P29597 B7ZKK7 P19525 Q8IW76
PDB IDs 3LXN 3LXP 3NYX 3NZ0 3ZON 4GFO 4GIH 4GII 4GJ2 4GJ3 4GVJ 1QU6 2A19 2A1A 3UIU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
3t3  carboxyl  coimmunoprecipitated  directed  f442a  functionally  gh  ghr  heretofore  hmw  immunoblotting  immunologically  immunoprecipitation  independently  jak1  jak2  jak3  janus  kd  member  mr  physically  preadipocytes  referred  signalling  step  terminus  tyrosine  whose 
c1qdc1  cds1  crebbp  ctnnd1  cul1  customized  dner  eef2  fzd2  fzd9  g93a  gastrocnemius  id2  inppl1  keep  loxl2  neuromuscular  pi3  pik3c2a  pik4ca  piki3r1  precede  presymptomatic  prkx  rac3  ripk4  snf1lk  sod1  tbl1x 
Tagcloud (Difference) ?
3t3  carboxyl  coimmunoprecipitated  directed  f442a  functionally  gh  ghr  heretofore  hmw  immunoblotting  immunologically  immunoprecipitation  independently  jak1  jak2  jak3  janus  kd  member  mr  physically  preadipocytes  referred  signalling  step  terminus  tyrosine  whose 
c1qdc1  cds1  crebbp  ctnnd1  cul1  customized  dner  eef2  fzd2  fzd9  g93a  gastrocnemius  id2  inppl1  keep  loxl2  neuromuscular  pi3  pik3c2a  pik4ca  piki3r1  precede  presymptomatic  prkx  rac3  ripk4  snf1lk  sod1  tbl1x 
Tagcloud (Intersection) ?