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TSG101 and DNMT1
Number of citations of the paper that reports this interaction (PubMedID
10888872
)
0
Data Source:
HPRD
(two hybrid, in vivo)
TSG101
DNMT1
Description
tumor susceptibility 101
DNA methyltransferase 1
Image
GO Annotations
Cellular Component
ESCRT I Complex
Nucleus
Nucleolus
Cytoplasm
Endosome
Early Endosome
Late Endosome
Multivesicular Body
Centrosome
Cytosol
Cytoskeleton
Plasma Membrane
Endosome Membrane
Membrane
Early Endosome Membrane
Late Endosome Membrane
Extracellular Exosome
Flemming Body
Heterochromatin
Female Germ Cell Nucleus
Nucleus
Nucleoplasm
Replication Fork
Pericentric Heterochromatin
Mitochondrion
Germ Cell Nucleus
Molecular Function
DNA Binding
Transcription Corepressor Activity
Protein Binding
Ubiquitin Protein Ligase Binding
Protein Homodimerization Activity
Ubiquitin Binding
Protein-containing Complex Binding
Virion Binding
Calcium-dependent Protein Binding
DNA Binding
Chromatin Binding
RNA Binding
DNA (cytosine-5-)-methyltransferase Activity
Protein Binding
Methyltransferase Activity
Zinc Ion Binding
Methyl-CpG Binding
DNA-methyltransferase Activity
Transferase Activity
Metal Ion Binding
LncRNA Binding
Promoter-specific Chromatin Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Growth
Extracellular Transport
Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity
Negative Regulation Of Cell Population Proliferation
Endosome To Lysosome Transport
Protein Transport
Macroautophagy
Viral Release From Host Cell
Cell Differentiation
Keratinocyte Differentiation
Multivesicular Body Assembly
Viral Budding Via Host ESCRT Complex
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Regulation Of MAP Kinase Activity
Viral Budding
Cell Division
Regulation Of Cell Cycle
Membrane Fission
Autophagosome Maturation
Positive Regulation Of Exosomal Secretion
Regulation Of Extracellular Exosome Assembly
Positive Regulation Of Viral Budding Via Host ESCRT Complex
Exosomal Secretion
Positive Regulation Of Ubiquitin-dependent Endocytosis
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
DNA Methylation-dependent Constitutive Heterochromatin Formation
DNA-templated Transcription
Regulation Of Gene Expression
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Methylation
Regulation Of Cell Population Proliferation
Epigenetic Programming Of Gene Expression
Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation
Negative Regulation Of DNA-templated Transcription
Cellular Response To Amino Acid Stimulus
Chromosomal DNA Methylation Maintenance Following DNA Replication
Cellular Response To Bisphenol A
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process
Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Involved In Phenotypic Switching
Pathways
Budding and maturation of HIV virion
Membrane binding and targetting of GAG proteins
Endosomal Sorting Complex Required For Transport (ESCRT)
HCMV Late Events
Late endosomal microautophagy
PRC2 methylates histones and DNA
NoRC negatively regulates rRNA expression
SUMOylation of DNA methylation proteins
DNA methylation
STAT3 nuclear events downstream of ALK signaling
Defective pyroptosis
Nuclear events stimulated by ALK signaling in cancer
Drugs
Procaine
Azacitidine
Procainamide
Flucytosine
Decitabine
Palifosfamide
Epigallocatechin gallate
Diseases
GWAS
Appendicular lean mass (
33097823
)
Birth weight (
31043758
)
Immature fraction of reticulocytes (
27863252
)
Narcolepsy (
24204295
)
Offspring birth weight (
31043758
)
Reticulocyte count (
27863252
)
Reticulocyte fraction of red cells (
27863252
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Interacting Genes
136 interacting genes:
AATF
ADRB2
AJUBA
AKAP9
AR
BAG4
BCAS3
BCR
BIRC2
CAGE1
CBY1
CCDC88B
CCHCR1
CCND3
CDKN1A
CDKN2D
CDS2
CEP55
CEP63
CHD7
CNOT7
DAXX
DMAP1
DMRTB1
DNMT1
DSCR9
DZIP3
EP300
FAM110A
FAM9B
GGA1
GGA3
GLI2
GLIS3
GMCL1
GOLM1
GPRC5B
GUCY1B2
HAUS1
HCK
HGS
HSH2D
INCA1
IQGAP1
IRF2BPL
ITPRID2
ITSN1
JUN
KIAA1328
KIF5A
KIFC3
KLK5
KLK6
KRT13
KRT15
KRT16
KRT18
KRT31
KRT34
KRT35
KRT75
LCN2
LENG8
LNX1
LRRFIP1
LRSAM1
MDM2
MGRN1
MKRN3
MTA3
MZB1
NR3C1
NUP214
OGT
PDCD6IP
PDLIM7
PIAS1
PIP4P2
PKNOX2
PPFIBP2
PPP1R13B
PRDM16
PRRC1
PRSS50
QKI
RAD18
RASL10B
RBPMS
RNF111
RNF126
RNF41
ROCK1
SCAMP3
SCARA5
SCGB3A1
SCNN1A
SH3GLB2
SHANK3
SNAPIN
SNCA
SNF8
SNX32
STK11
SYCE1
TAX1BP1
TEX11
TFF1
TFIP11
THRB
THRSP
TNF
TNIP2
TNNT3
TOM1L1
TP53
TRAIP
TRIM23
TRIM35
TRIM46
TRIM54
TRIM74
TRIML2
UBA52
UBC
USF3
USHBP1
VPS11
VPS28
VPS36
VPS37A
VPS37B
VPS37C
VPS37D
WASHC1
YLPM1
ZWINT
53 interacting genes:
AKT1
BAZ2A
BRAP
CBX1
CEBPA
CSNK2B
DAXX
DCAF5
DMAP1
DNMT3A
DNMT3B
DYNLL1
E2F6
EED
EEF1A1
ENSA
EZH2
FBP1
GSK3B
H2BC3
H3-4
HDAC1
HDAC2
HELLS
HMGB1
L3MBTL3
LASP1
LCOR
MCRIP1
MECP2
NGRN
NRIP1
PCLAF
PCNA
PEBP1
PHC2
PICK1
PRKAA2
RB1
RGS6
RPS6KA6
RUNX1
RUNX1T1
SETD7
SNHG6
SUMO2
SUV39H1
TRIM27
TRIM3
TSG101
UBB
UBC
YWHAQ
Entrez ID
7251
1786
HPRD ID
03229
00532
Ensembl ID
ENSG00000074319
ENSG00000130816
Uniprot IDs
Q99816
I6L9H2
P26358
Q59FP7
PDB IDs
1KPP
1KPQ
1M4P
1M4Q
1S1Q
2F0R
3IV1
3OBQ
3OBS
3OBU
3OBX
3P9G
3P9H
4EJE
4YC1
4ZNY
5VKG
6UD0
6VME
7NLC
7ZLX
3EPZ
3PTA
3SWR
4WXX
4YOC
4Z96
4Z97
5WVO
5YDR
6K3A
6L1F
6X9I
6X9J
6X9K
7SFC
7SFD
7SFE
7SFF
7SFG
7XI9
7XIB
8V9U
8XQC
Enriched GO Terms of Interacting Partners
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Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Multivesicular Body Organization
Multivesicular Body Assembly
Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway
Endosome Transport Via Multivesicular Body Sorting Pathway
Vacuolar Transport
Ubiquitin Protein Ligase Activity
Multivesicular Body Sorting Pathway
Autophagy
Cytosol
Late Endosome To Vacuole Transport
Viral Budding
Endosome Organization
Establishment Of Protein Localization To Vacuole
Intracellular Protein Localization
Membrane Fission
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Protein Localization To Vacuole
Organelle Organization
ESCRT I Complex
Viral Budding Via Host ESCRT Complex
Programmed Cell Death
Cell Death
Endosomal Transport
Intracellular Protein Transport
Macroautophagy
Zinc Ion Binding
Protein Ubiquitination
Protein Transport
Vesicle-mediated Transport
Protein Modification By Small Protein Conjugation
Apoptotic Process
Establishment Of Protein Localization
Cellular Localization
Cytoplasm
Cytoskeleton
Structural Constituent Of Skin Epidermis
Endosome Membrane
Protein Binding
Intracellular Transport
Protein Localization To Organelle
Intermediate Filament Cytoskeleton Organization
Keratin Filament
Intermediate Filament-based Process
Ubiquitin Binding
Intermediate Filament Organization
Positive Regulation Of Catabolic Process
Regulation Of Protein Metabolic Process
Viral Process
Post-translational Protein Modification
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Chromatin Organization
Negative Regulation Of Metabolic Process
Chromatin Remodeling
Nucleoplasm
Heterochromatin Formation
Transcription Corepressor Activity
Chromatin Binding
Epigenetic Regulation Of Gene Expression
Nucleus
Negative Regulation Of Transcription By RNA Polymerase II
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Primary Metabolic Process
Heterochromatin
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Chromatin Silencing Complex
Cellular Response To Stress
Facultative Heterochromatin Formation
DNA Methylation-dependent Constitutive Heterochromatin Formation
Transcription Corepressor Binding
Enzyme Binding
Regulation Of Transcription By RNA Polymerase II
Constitutive Heterochromatin Formation
Rhythmic Process
DNA-binding Transcription Factor Binding
Cellular Response To Xenobiotic Stimulus
Regulation Of Proteolysis
Epigenetic Programming Of Gene Expression
DNA Binding
Macromolecule Metabolic Process
Response To Lipid
Chromosome
Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation
ESC/E(Z) Complex
Protein Tag Activity
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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