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TSG101 and MZB1
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
TSG101
MZB1
Description
tumor susceptibility 101
marginal zone B and B1 cell specific protein
Image
GO Annotations
Cellular Component
ESCRT I Complex
Nucleus
Nucleolus
Cytoplasm
Endosome
Early Endosome
Late Endosome
Multivesicular Body
Centrosome
Cytosol
Cytoskeleton
Plasma Membrane
Endosome Membrane
Membrane
Early Endosome Membrane
Late Endosome Membrane
Extracellular Exosome
Flemming Body
Extracellular Region
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Lumen
Endoplasmic Reticulum Chaperone Complex
Molecular Function
DNA Binding
Transcription Corepressor Activity
Protein Binding
Ubiquitin Protein Ligase Binding
Protein Homodimerization Activity
Ubiquitin Binding
Protein-containing Complex Binding
Virion Binding
Calcium-dependent Protein Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Growth
Extracellular Transport
Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity
Negative Regulation Of Cell Population Proliferation
Endosome To Lysosome Transport
Protein Transport
Macroautophagy
Viral Release From Host Cell
Cell Differentiation
Keratinocyte Differentiation
Multivesicular Body Assembly
Viral Budding Via Host ESCRT Complex
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Regulation Of MAP Kinase Activity
Viral Budding
Cell Division
Regulation Of Cell Cycle
Membrane Fission
Autophagosome Maturation
Positive Regulation Of Exosomal Secretion
Regulation Of Extracellular Exosome Assembly
Positive Regulation Of Viral Budding Via Host ESCRT Complex
Exosomal Secretion
Positive Regulation Of Ubiquitin-dependent Endocytosis
Positive Regulation Of Immunoglobulin Production
Apoptotic Process
Positive Regulation Of Cell Population Proliferation
Regulation Of B Cell Proliferation
Integrin Activation
Regulation Of Cell Population Proliferation
Regulation Of Insulin Receptor Signaling Pathway
Pathways
Budding and maturation of HIV virion
Membrane binding and targetting of GAG proteins
Endosomal Sorting Complex Required For Transport (ESCRT)
HCMV Late Events
Late endosomal microautophagy
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Malaria (
31844061
)
Interacting Genes
136 interacting genes:
AATF
ADRB2
AJUBA
AKAP9
AR
BAG4
BCAS3
BCR
BIRC2
CAGE1
CBY1
CCDC88B
CCHCR1
CCND3
CDKN1A
CDKN2D
CDS2
CEP55
CEP63
CHD7
CNOT7
DAXX
DMAP1
DMRTB1
DNMT1
DSCR9
DZIP3
EP300
FAM110A
FAM9B
GGA1
GGA3
GLI2
GLIS3
GMCL1
GOLM1
GPRC5B
GUCY1B2
HAUS1
HCK
HGS
HSH2D
INCA1
IQGAP1
IRF2BPL
ITPRID2
ITSN1
JUN
KIAA1328
KIF5A
KIFC3
KLK5
KLK6
KRT13
KRT15
KRT16
KRT18
KRT31
KRT34
KRT35
KRT75
LCN2
LENG8
LNX1
LRRFIP1
LRSAM1
MDM2
MGRN1
MKRN3
MTA3
MZB1
NR3C1
NUP214
OGT
PDCD6IP
PDLIM7
PIAS1
PIP4P2
PKNOX2
PPFIBP2
PPP1R13B
PRDM16
PRRC1
PRSS50
QKI
RAD18
RASL10B
RBPMS
RNF111
RNF126
RNF41
ROCK1
SCAMP3
SCARA5
SCGB3A1
SCNN1A
SH3GLB2
SHANK3
SNAPIN
SNCA
SNF8
SNX32
STK11
SYCE1
TAX1BP1
TEX11
TFF1
TFIP11
THRB
THRSP
TNF
TNIP2
TNNT3
TOM1L1
TP53
TRAIP
TRIM23
TRIM35
TRIM46
TRIM54
TRIM74
TRIML2
UBA52
UBC
USF3
USHBP1
VPS11
VPS28
VPS36
VPS37A
VPS37B
VPS37C
VPS37D
WASHC1
YLPM1
ZWINT
4 interacting genes:
CASP2
CASP9
MAPK6
TSG101
Entrez ID
7251
51237
HPRD ID
03229
17815
Ensembl ID
ENSG00000074319
ENSG00000170476
Uniprot IDs
Q99816
B3KQ72
Q8WU39
PDB IDs
1KPP
1KPQ
1M4P
1M4Q
1S1Q
2F0R
3IV1
3OBQ
3OBS
3OBU
3OBX
3P9G
3P9H
4EJE
4YC1
4ZNY
5VKG
6UD0
6VME
7NLC
7ZLX
7AAH
Enriched GO Terms of Interacting Partners
?
Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Multivesicular Body Organization
Multivesicular Body Assembly
Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway
Endosome Transport Via Multivesicular Body Sorting Pathway
Vacuolar Transport
Ubiquitin Protein Ligase Activity
Multivesicular Body Sorting Pathway
Autophagy
Cytosol
Late Endosome To Vacuole Transport
Viral Budding
Endosome Organization
Establishment Of Protein Localization To Vacuole
Intracellular Protein Localization
Membrane Fission
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Protein Localization To Vacuole
Organelle Organization
ESCRT I Complex
Viral Budding Via Host ESCRT Complex
Programmed Cell Death
Cell Death
Endosomal Transport
Intracellular Protein Transport
Macroautophagy
Zinc Ion Binding
Protein Ubiquitination
Protein Transport
Vesicle-mediated Transport
Protein Modification By Small Protein Conjugation
Apoptotic Process
Establishment Of Protein Localization
Cellular Localization
Cytoplasm
Cytoskeleton
Structural Constituent Of Skin Epidermis
Endosome Membrane
Protein Binding
Intracellular Transport
Protein Localization To Organelle
Intermediate Filament Cytoskeleton Organization
Keratin Filament
Intermediate Filament-based Process
Ubiquitin Binding
Intermediate Filament Organization
Positive Regulation Of Catabolic Process
Regulation Of Protein Metabolic Process
Viral Process
Post-translational Protein Modification
Positive Regulation Of Neuron Apoptotic Process
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Cysteine-type Endopeptidase Activity
Cysteine-type Peptidase Activity
Intrinsic Apoptotic Signaling Pathway
Signal Transduction In Response To DNA Damage
Protein Processing
Endopeptidase Complex
Apoptosome
Caspase Complex
Septin Cytoskeleton
Positive Regulation Of Ubiquitin-dependent Endocytosis
Positive Regulation Of Viral Budding Via Host ESCRT Complex
Protein Metabolic Process
Exosomal Secretion
Luteolysis
Regulation Of Neuron Apoptotic Process
Proteolysis
Response To Anesthetic
Glial Cell Apoptotic Process
Response To Indole-3-methanol
Regulation Of Extracellular Exosome Assembly
Protein Maturation
Apoptotic Signaling Pathway
Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity
Response To Cobalt Ion
Virion Binding
Fibroblast Apoptotic Process
ESCRT I Complex
Negative Regulation Of Protein Tyrosine Kinase Activity
Negative Regulation Of Signaling Receptor Activity
Positive Regulation Of Exosomal Secretion
Ectopic Germ Cell Programmed Cell Death
Peptidase Activity
Neural Retina Development
Intracellular Signal Transduction
Protein Kinase Binding
MAP Kinase Activity
Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Regulation Of Exosomal Secretion
Negative Regulation Of Peptidyl-tyrosine Phosphorylation
Programmed Cell Death Involved In Cell Development
Positive Regulation Of Execution Phase Of Apoptosis
Viral Budding Via Host ESCRT Complex
Regulation Of Protein Tyrosine Kinase Activity
Platelet Formation
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Apoptotic Process
Macromolecule Metabolic Process
Execution Phase Of Apoptosis
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Tagcloud (Intersection)
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