FBXW5 and SASS6

Number of citations of the paper that reports this interaction (PMID 21725316)
24

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, enzymatic study)

		FBXW5	SASS6
Gene Name		F-box and WD repeat domain containing 5	spindle assembly 6 homolog (C. elegans)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm SCF Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex	Centrosome Centriole Deuterosome
	Molecular Function	Protein Binding Protein Kinase Binding	Protein Binding
	Biological Process	Mitotic Nuclear Division Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Centrosome Duplication	Centriole Replication Centrosome Duplication
Pathways		Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: ADAMTSL4 KRT31 KRT40 KRTAP10-3 KRTAP10-8 KRTAP4-12 KRTAP9-4 MDFI MYB NLK NOTCH2NL SASS6 SKP1 TRIM27 TSC2 UBE2R2	1 interactors: FBXW5
Entrez ID		54461	163786
HPRD ID		10955	10907
Ensembl ID		ENSG00000159069	ENSG00000156876
Uniprot IDs		Q969U6	F5GXY5 Q6UVJ0
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Wnt Signaling Pathway Protein Monoubiquitination Regulation Of Wnt Signaling Pathway	SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Centrosome Duplication Centrosome Cycle Centrosome Organization Microtubule Organizing Center Organization
Tagcloud ?		autophagic autophagy brains competes cul4 da dopaminergic dysfunctional dysregulated exclusive hydroxydopamine implicating l1 mortem mtor neurochem neurodegeneration ohda opposition os oxi parkinson pathogenic proteasomal stabilize stabilizes tnfaip8 tsc2 tuberous
Tagcloud (Difference) ?		autophagic autophagy brains competes cul4 da dopaminergic dysfunctional dysregulated exclusive hydroxydopamine implicating l1 mortem mtor neurochem neurodegeneration ohda opposition os oxi parkinson pathogenic proteasomal stabilize stabilizes tnfaip8 tsc2 tuberous
Tagcloud (Intersection) ?