FBXW5

Gene Name		F-box and WD repeat domain containing 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm SCF Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Protein Kinase Binding
	Biological Process	Mitotic Nuclear Division Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Centrosome Duplication
Pathways		Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS
Protein-protein Interactions		16 interactors: ADAMTSL4 KRT31 KRT40 KRTAP10-3 KRTAP10-8 KRTAP4-12 KRTAP9-4 MDFI MYB NLK NOTCH2NL SASS6 SKP1 TRIM27 TSC2 UBE2R2
Entrez ID		54461
HPRD ID		10955
Ensembl ID		ENSG00000159069
Uniprot IDs		Q969U6
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Wnt Signaling Pathway Protein Monoubiquitination Regulation Of Wnt Signaling Pathway
Tagcloud ?		autophagic autophagy brains competes cul4 da dopaminergic dysfunctional dysregulated exclusive hydroxydopamine implicating l1 mortem mtor neurochem neurodegeneration ohda opposition os oxi parkinson pathogenic proteasomal stabilize stabilizes tnfaip8 tsc2 tuberous