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FBXW5
Description
F-box and WD repeat domain containing 5
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
SCF Ubiquitin Ligase Complex
Cul4-RING E3 Ubiquitin Ligase Complex
Molecular Function
Protein Binding
Protein Kinase Binding
Biological Process
Regulation Of Mitotic Nuclear Division
Regulation Of Cell Cycle Process
Regulation Of Centrosome Duplication
Protein Ubiquitination
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways
Association of TriC/CCT with target proteins during biosynthesis
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Heel bone mineral density (
30598549
)
Keratoconus (
33649486
)
Plateletcrit (
32888494
)
Novel Interacting Genes
1 novel interacting genes:
CYP1A1
Interacting Genes
36 interacting genes:
ADAMTSL4
CYSRT1
EFEMP2
FAM168A
FBLN2
KRT31
KRT34
KRT37
KRT40
KRTAP1-1
KRTAP1-3
KRTAP10-3
KRTAP10-8
KRTAP10-9
KRTAP12-3
KRTAP4-1
KRTAP4-12
KRTAP6-3
KRTAP9-3
KRTAP9-4
MDFI
MID2
MTUS2
MYB
NBPF19
NLK
NOTCH2NLA
PLEKHF2
S100B
SASS6
SEC23B
SKP1
TRIM27
TSC2
UBE2R2
VWC2
Entrez ID
54461
HPRD ID
10955
Ensembl ID
ENSG00000159069
Uniprot IDs
Q969U6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Keratin Filament
Intermediate Filament
Structural Constituent Of Skin Epidermis
Intermediate Filament Organization
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Interstitial Matrix
Cytosol
Structural Molecule Activity
Supramolecular Fiber Organization
Suppression Of Viral Release By Host
Negative Regulation Of Viral Transcription
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