TNNI1 and TNNT1

Number of citations of the paper that reports this interaction (PMID 8987992)
4

Data Source:
HPRD (in vivo)

		TNNI1	TNNT1
Gene Name		troponin I type 1 (skeletal, slow)	troponin T type 1 (skeletal, slow)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Troponin Complex	Cytosol Troponin Complex
	Molecular Function	Actin Binding Metal Ion Binding	Tropomyosin Binding Troponin T Binding
	Biological Process	Regulation Of Striated Muscle Contraction Muscle Filament Sliding Ventricular Cardiac Muscle Tissue Morphogenesis	Skeletal Muscle Contraction Muscle Filament Sliding Slow-twitch Skeletal Muscle Fiber Contraction Negative Regulation Of Muscle Contraction
Pathways		Striated Muscle Contraction	Striated Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: ACTA1 CCDC85B EIF3I MDFI PKD2L1 PNMA1 TNNC1 TNNT1 TNNT2 TRIM55 TRIM63	61 interactors: ARMC8 BLOC1S2 BMPR1B C2orf44 CCDC136 CCDC85B CHD3 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HMP19 HSP90AB1 IMMT KAT5 KRT40 LARP1 LDOC1 MARS MORF4L1 NACAD NAGK NFE2L2 NINL OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TPM1 TPM3 TRA2A TRIM63 UBE2D1 VIM ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768
Entrez ID		7135	7138
HPRD ID		01842	01841
Ensembl ID		ENSG00000159173	ENSG00000105048
Uniprot IDs		P19237	P13805
PDB IDs
Enriched GO Terms of Interacting Partners?		Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Actin Filament-based Movement Muscle Contraction Muscle System Process Negative Regulation Of ATPase Activity Skeletal Muscle Adaptation Regulation Of Muscle Contraction Skeletal Muscle Contraction Actin Filament-based Process Regulation Of ATPase Activity Musculoskeletal Movement Ventricular Cardiac Muscle Tissue Morphogenesis Muscle Organ Development Ventricular Cardiac Muscle Tissue Development Cardiac Muscle Tissue Morphogenesis Striated Muscle Tissue Development Muscle Tissue Morphogenesis Response To Metal Ion Muscle Tissue Development Muscle Organ Morphogenesis Cardiac Ventricle Morphogenesis Regulation Of Muscle Filament Sliding Speed Myofibril Assembly Striated Muscle Contraction Skeletal Muscle Fiber Adaptation Detection Of Chemical Stimulus Involved In Sensory Perception Of Sour Taste Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Cardiac Ventricle Development Response To Inorganic Substance Actomyosin Structure Organization Muscle Structure Development Regulation Of Muscle Filament Sliding Diaphragm Contraction Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Cardiac Chamber Development Sensory Perception Of Sour Taste Involuntary Skeletal Muscle Contraction Striated Muscle Cell Development Skeletal Muscle Atrophy Muscle Cell Development Slow-twitch Skeletal Muscle Fiber Contraction Skeletal Muscle Thin Filament Assembly Striated Muscle Atrophy Cardiac Muscle Tissue Development Movement Of Cell Or Subcellular Component Cellular Response To Acidic PH Muscle Atrophy Atrial Cardiac Muscle Tissue Morphogenesis	Muscle Filament Sliding Actin-myosin Filament Sliding Actin-mediated Cell Contraction Actin Filament-based Movement Muscle System Process Regulation Of Metabolic Process Muscle Contraction Regulation Of Gene Expression Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Muscle Contraction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Ventricular Cardiac Muscle Tissue Morphogenesis Movement Of Cell Or Subcellular Component Ventricular Cardiac Muscle Tissue Development Regulation Of Cellular Process Cardiac Muscle Tissue Morphogenesis Signal Transduction Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Cellular Response To Organic Substance Muscle Tissue Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Regulation Of RNA Metabolic Process Muscle Organ Morphogenesis Cardiac Ventricle Morphogenesis Cellular Macromolecule Biosynthetic Process BMP Signaling Pathway Positive Regulation Of Gene Expression Macromolecule Biosynthetic Process Signaling Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Striated Muscle Contraction Positive Regulation Of Cellular Biosynthetic Process Cell Communication Cellular Response To Transforming Growth Factor Beta Stimulus RNA Metabolic Process RNA Biosynthetic Process Response To Transforming Growth Factor Beta Cardiac Muscle Tissue Development Primary MiRNA Processing Cellular Response To Stimulus Regulation Of Cellular Component Organization Positive Regulation Of Apoptotic Signaling Pathway Response To Stimulus
Tagcloud ?			apoc2 atp1a3 bckdha cgb cgm2 cyp2a d19s112 d19s116 d19s117 d19s118 d19s119 d19s19 d19s2 d19s37 d19s50 d19s51 d19s54 d19s55 d19s6 d19s62 d19s63 d19s7 d19s8 d19s9 manb pepd prkcg psg1 pw39
Tagcloud (Difference) ?			apoc2 atp1a3 bckdha cgb cgm2 cyp2a d19s112 d19s116 d19s117 d19s118 d19s119 d19s19 d19s2 d19s37 d19s50 d19s51 d19s54 d19s55 d19s6 d19s62 d19s63 d19s7 d19s8 d19s9 manb pepd prkcg psg1 pw39
Tagcloud (Intersection) ?