TNNI1 and SYCE1L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TNNI1	SYCE1L
Description		troponin I1, slow skeletal type	synaptonemal complex central element protein 1 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex	Synaptonemal Complex Intermediate Filament Cytoskeleton
	Molecular Function	Actin Binding Protein Binding
	Biological Process	Skeletal Muscle Contraction Regulation Of Striated Muscle Contraction Transition Between Fast And Slow Fiber Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction	Synaptonemal Complex Assembly Meiotic Cell Cycle Synaptonemal Complex Organization
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS			Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		46 interacting genes: ACTA1 ANKRD11 ARMC7 C2orf68 CABP2 CABP5 CCDC102B CCDC57 CCDC85B CDCA7L CEP19 CETN3 CTNNA3 DCAF11 DRC8 EAF1 EIF1AD EIF3B ENKD1 ESRRG KIFC3 L3MBTL2 MBD3 MCRS1 MDFI MNS1 MTUS2 PIH1D2 PIK3R3 PKD2L1 PNMA1 POLR1C PRKAB2 SAT1 SCNM1 SPANXN2 SYCE1L TNNC1 TNNT1 TNNT2 TPM3 TRIM41 TRIM55 TRIM63 USP20 ZNF76	36 interacting genes: ALDH18A1 ANKRD36 ATF5 BFSP2 BOLL C1orf216 C22orf39 CALN1 CCDC146 CCDC196 CCHCR1 CENPP CST1 CYTH4 DPPA3 EPC1 FGA HSF2BP KCNIP2 KIAA1328 LCA5L LNX1 MED10 NOL4 NTAQ1 ODF1 OIP5 PFDN5 SCHIP1 SLC7A8 SMARCD1 SPHKAP SRSF10 TNNI1 TRAPPC13 ZNF526
Entrez ID		7135	100130958
HPRD ID		01842
Ensembl ID		ENSG00000159173	ENSG00000205078
Uniprot IDs		P19237	A8MT33
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoskeleton Troponin Complex Centrosome Muscle Contraction Cardiac Troponin Complex Troponin I Binding Troponin T Binding Muscle System Process Centriole Transition Between Fast And Slow Fiber Striated Muscle Thin Filament Microtubule Regulation Of Skeletal Muscle Adaptation Sarcomere Contractile Muscle Fiber Tropomyosin Binding Regulation Of Muscle System Process Cytoplasm Muscle Filament Sliding Protein Binding Actin-myosin Filament Sliding Spindle Pole
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