TNNT1 and WDCP

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		TNNT1	WDCP
Description		troponin T1, slow skeletal type	WD repeat and coiled coil containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex
	Molecular Function	Protein Binding Tropomyosin Binding Troponin T Binding	Protein Binding Kinase Binding
	Biological Process	Skeletal Muscle Contraction Regulation Of Muscle Contraction Transition Between Fast And Slow Fiber Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction	Protein Complex Oligomerization
Pathways		Striated Muscle Contraction	Signaling by ALK fusions and activated point mutants
Drugs
Diseases		Nemaline myopathy
GWAS		Height ( 31562340)	Feeling guilty ( 29500382)
Interacting Genes		69 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 CLIP4 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT27 KRT40 LARP1 LDOC1 MARS1 MORF4L1 MYOM2 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SBK3 SDCBP2 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TNNT2 TPM1 TPM3 TRA2A TRIM63 TSPYL2 TULP3 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768	12 interacting genes: CSNK1E CSNK1G1 CSNK1G2 DYNC1I1 HCK MED31 PDPK1 PRKAR1A RAB35 RPS27 TAB1 TNNT1
Entrez ID		7138	80304
HPRD ID		01841	07972
Ensembl ID		ENSG00000105048	ENSG00000163026
Uniprot IDs		P13805	Q9H6R7
PDB IDs
Enriched GO Terms of Interacting Partners?		Troponin Complex Cardiac Muscle Contraction Ventricular Cardiac Muscle Tissue Morphogenesis SMAD Binding Muscle System Process Cardiac Troponin Complex Cardiac Muscle Tissue Morphogenesis Muscle Contraction Troponin T Binding Muscle Filament Sliding I-SMAD Binding Muscle Tissue Morphogenesis Actin-myosin Filament Sliding Striated Muscle Contraction Protein Binding Skeletal Muscle Contraction Primary MiRNA Processing Homomeric SMAD Protein Complex Actin-mediated Cell Contraction Contractile Muscle Fiber Regulation Of Hematopoietic Stem Cell Differentiation Tissue Morphogenesis Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration Troponin C Binding Regulation Of Muscle System Process Regulation Of Muscle Contraction Sarcomere Response To Muramyl Dipeptide Regulation Of Primary Metabolic Process Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Troponin I Binding Muscle Thin Filament Tropomyosin Cytosol Actin Filament-based Movement Regulation Of Cell Differentiation Regulation Of Nucleobase-containing Compound Metabolic Process Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Cytoskeleton Organization Transforming Growth Factor Beta Receptor Activity, Type I Disordered Domain Specific Binding Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process R-SMAD Binding Cytoplasm Negative Regulation Of Smooth Muscle Cell Migration Regulation Of Stem Cell Differentiation Calcium-dependent Protein Binding SMAD Protein Complex Trophoblast Cell Migration Transition Between Fast And Slow Fiber Cardiac Myofibril	Cytosol Protein Kinase Activity Nucleotide Binding Protein Serine Kinase Activity Kinase Activity Positive Regulation Of Canonical Wnt Signaling Pathway Protein Phosphorylation Phosphorylation Positive Regulation Of Wnt Signaling Pathway Protein Serine/threonine Kinase Activity Endocytosis Sarcomere Organization Cellular Response To Nerve Growth Factor Stimulus Response To Nerve Growth Factor Regulation Of Canonical Wnt Signaling Pathway 3-phosphoinositide-dependent Protein Kinase Activity Slow-twitch Skeletal Muscle Fiber Contraction Cellular Response To Growth Factor Stimulus Wnt Signaling Pathway Import Into Cell Positive Regulation Of Cell Communication Vesicle-mediated Transport Positive Regulation Of Signaling Response To Growth Factor Regulation Of Wnt Signaling Pathway Cell Surface Receptor Signaling Pathway
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