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TNNT1 and NACAD
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
TNNT1
NACAD
Gene Name
troponin T type 1 (skeletal, slow)
NAC alpha domain containing
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Troponin Complex
Nucleus
Cytoplasm
Molecular Function
Tropomyosin Binding
Troponin T Binding
Biological Process
Skeletal Muscle Contraction
Muscle Filament Sliding
Slow-twitch Skeletal Muscle Fiber Contraction
Negative Regulation Of Muscle Contraction
Protein Transport
Pathways
Striated Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions
61 interactors:
ARMC8
BLOC1S2
BMPR1B
C2orf44
CCDC136
CCDC85B
CHD3
DDX5
EEF1G
FAF1
FXR2
FYN
HAP1
HMGXB4
HMP19
HSP90AB1
IMMT
KAT5
KRT40
LARP1
LDOC1
MARS
MORF4L1
NACAD
NAGK
NFE2L2
NINL
OSBP2
OSM
PI4KA
PLEKHF1
PNMA1
PPFIA1
PRKG1
PSMC5
SEC31A
SERPINA4
SH3GL3
SMAD1
SMAD2
SMURF1
SNW1
TBPL1
TFIP11
TGFBR1
TMEM98
TNNC1
TNNI1
TNNI2
TNNI3
TPM1
TPM3
TRA2A
TRIM63
UBE2D1
VIM
ZC3H15
ZKSCAN5
ZMYND19
ZNF250
ZNF768
8 interactors:
CBLC
HDAC6
MAP4K2
NR4A1
PTK2
RPS27
TNNT1
YAE1D1
Entrez ID
7138
23148
HPRD ID
01841
Ensembl ID
ENSG00000105048
ENSG00000136274
Uniprot IDs
P13805
O15069
PDB IDs
Enriched GO Terms of Interacting Partners
?
Muscle Filament Sliding
Actin-myosin Filament Sliding
Actin-mediated Cell Contraction
Actin Filament-based Movement
Muscle System Process
Regulation Of Metabolic Process
Muscle Contraction
Regulation Of Gene Expression
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Muscle Contraction
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Ventricular Cardiac Muscle Tissue Morphogenesis
Movement Of Cell Or Subcellular Component
Ventricular Cardiac Muscle Tissue Development
Regulation Of Cellular Process
Cardiac Muscle Tissue Morphogenesis
Signal Transduction
Regulation Of Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Gene Expression
Cellular Response To Organic Substance
Muscle Tissue Morphogenesis
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions
Regulation Of RNA Metabolic Process
Muscle Organ Morphogenesis
Cardiac Ventricle Morphogenesis
Cellular Macromolecule Biosynthetic Process
BMP Signaling Pathway
Positive Regulation Of Gene Expression
Macromolecule Biosynthetic Process
Signaling
Transcription, DNA-templated
Positive Regulation Of Cellular Metabolic Process
Striated Muscle Contraction
Positive Regulation Of Cellular Biosynthetic Process
Cell Communication
Cellular Response To Transforming Growth Factor Beta Stimulus
RNA Metabolic Process
RNA Biosynthetic Process
Response To Transforming Growth Factor Beta
Cardiac Muscle Tissue Development
Primary MiRNA Processing
Cellular Response To Stimulus
Regulation Of Cellular Component Organization
Positive Regulation Of Apoptotic Signaling Pathway
Response To Stimulus
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
Organelle Localization
Endothelial Cell Migration
Regulation Of Catalytic Activity
Epithelial Cell Migration
Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death
Hsp90 Deacetylation
Epithelium Migration
Regulation Of Receptor Activity
Response To Growth Factor
Positive Regulation Of Chaperone-mediated Protein Complex Assembly
Polyubiquitinated Misfolded Protein Transport
Regulation Of Proteolysis
Regulation Of Epithelial Cell Migration
Regulation Of Protein Kinase Activity
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Ameboidal-type Cell Migration
Netrin-activated Signaling Pathway
Negative Regulation Of Hydrogen Peroxide Metabolic Process
Negative Regulation Of Catalytic Activity
Regulation Of Kinase Activity
Innate Immune Response
Negative Regulation Of Cellular Protein Metabolic Process
Establishment Of Localization In Cell
Cellular Macromolecule Catabolic Process
Protein Complex Disassembly
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Synapse Assembly
Slow-twitch Skeletal Muscle Fiber Contraction
Aggresome Assembly
Tubulin Deacetylation
Positive Regulation Of Oxidative Stress-induced Cell Death
Peptidyl-lysine Deacetylation
Signal Complex Assembly
Fc Receptor Signaling Pathway
Cellular Response To Misfolded Protein
Regulation Of Protein Phosphorylation
Cellular Localization
Positive Regulation Of Receptor Biosynthetic Process
Regulation Of Hydrogen Peroxide Metabolic Process
Regulation Of MAP Kinase Activity
Cellular Protein Metabolic Process
Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity
Response To Misfolded Protein
Establishment Of Organelle Localization
Positive Regulation Of Cellular Metabolic Process
Angiogenesis
Positive Regulation Of Cell Migration
Tagcloud
?
apoc2
atp1a3
bckdha
cgb
cgm2
cyp2a
d19s112
d19s116
d19s117
d19s118
d19s119
d19s19
d19s2
d19s37
d19s50
d19s51
d19s54
d19s55
d19s6
d19s62
d19s63
d19s7
d19s8
d19s9
manb
pepd
prkcg
psg1
pw39
Tagcloud (Difference)
?
apoc2
atp1a3
bckdha
cgb
cgm2
cyp2a
d19s112
d19s116
d19s117
d19s118
d19s119
d19s19
d19s2
d19s37
d19s50
d19s51
d19s54
d19s55
d19s6
d19s62
d19s63
d19s7
d19s8
d19s9
manb
pepd
prkcg
psg1
pw39
Tagcloud (Intersection)
?