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TNNI1 and TNNT2
Number of citations of the paper that reports this interaction (PMID
15542288
)
40
Data Source:
BioGRID
(two hybrid)
TNNI1
TNNT2
Gene Name
troponin I type 1 (skeletal, slow)
troponin T type 2 (cardiac)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Troponin Complex
Cytosol
Troponin Complex
Striated Muscle Thin Filament
Sarcomere
Molecular Function
Actin Binding
Metal Ion Binding
Actin Binding
Structural Constituent Of Cytoskeleton
Tropomyosin Binding
ATPase Activity
Troponin C Binding
Troponin I Binding
Biological Process
Regulation Of Striated Muscle Contraction
Muscle Filament Sliding
Ventricular Cardiac Muscle Tissue Morphogenesis
Regulation Of Muscle Contraction
Regulation Of Heart Contraction
Metabolic Process
Muscle Filament Sliding
Negative Regulation Of ATPase Activity
Positive Regulation Of ATPase Activity
Sarcomere Organization
Response To Calcium Ion
Atrial Cardiac Muscle Tissue Morphogenesis
Ventricular Cardiac Muscle Tissue Morphogenesis
Pathways
Striated Muscle Contraction
Striated Muscle Contraction
Drugs
Diseases
GWAS
Cardiac Troponin-T levels (
23247143
)
Protein-Protein Interactions
11 interactors:
ACTA1
CCDC85B
EIF3I
MDFI
PKD2L1
PNMA1
TNNC1
TNNT1
TNNT2
TRIM55
TRIM63
10 interactors:
APP
KDM1A
MAP3K5
MORF4L2
NOTCH3
PRKCA
TNNC1
TNNI1
TNNI3
TPM1
Entrez ID
7135
7139
HPRD ID
01842
01844
Ensembl ID
ENSG00000159173
ENSG00000118194
Uniprot IDs
P19237
P45379
Q15607
PDB IDs
1J1D
1J1E
Enriched GO Terms of Interacting Partners
?
Actin-myosin Filament Sliding
Muscle Filament Sliding
Actin-mediated Cell Contraction
Actin Filament-based Movement
Muscle Contraction
Muscle System Process
Negative Regulation Of ATPase Activity
Skeletal Muscle Adaptation
Regulation Of Muscle Contraction
Skeletal Muscle Contraction
Actin Filament-based Process
Regulation Of ATPase Activity
Musculoskeletal Movement
Ventricular Cardiac Muscle Tissue Morphogenesis
Muscle Organ Development
Ventricular Cardiac Muscle Tissue Development
Cardiac Muscle Tissue Morphogenesis
Striated Muscle Tissue Development
Muscle Tissue Morphogenesis
Response To Metal Ion
Muscle Tissue Development
Muscle Organ Morphogenesis
Cardiac Ventricle Morphogenesis
Regulation Of Muscle Filament Sliding Speed
Myofibril Assembly
Striated Muscle Contraction
Skeletal Muscle Fiber Adaptation
Detection Of Chemical Stimulus Involved In Sensory Perception Of Sour Taste
Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions
Cardiac Ventricle Development
Response To Inorganic Substance
Actomyosin Structure Organization
Muscle Structure Development
Regulation Of Muscle Filament Sliding
Diaphragm Contraction
Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation
Cardiac Chamber Development
Sensory Perception Of Sour Taste
Involuntary Skeletal Muscle Contraction
Striated Muscle Cell Development
Skeletal Muscle Atrophy
Muscle Cell Development
Slow-twitch Skeletal Muscle Fiber Contraction
Skeletal Muscle Thin Filament Assembly
Striated Muscle Atrophy
Cardiac Muscle Tissue Development
Movement Of Cell Or Subcellular Component
Cellular Response To Acidic PH
Muscle Atrophy
Atrial Cardiac Muscle Tissue Morphogenesis
Actin-myosin Filament Sliding
Muscle Filament Sliding
Ventricular Cardiac Muscle Tissue Morphogenesis
Actin-mediated Cell Contraction
Regulation Of Muscle Contraction
Ventricular Cardiac Muscle Tissue Development
Cardiac Muscle Tissue Morphogenesis
Muscle Tissue Morphogenesis
Actin Filament-based Movement
Muscle Organ Morphogenesis
Cardiac Ventricle Morphogenesis
Cardiac Ventricle Development
Cardiac Chamber Development
Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions
Cardiovascular System Development
Regulation Of ATPase Activity
Cardiac Muscle Tissue Development
Muscle Structure Development
Cardiac Muscle Contraction
Muscle Contraction
Heart Morphogenesis
Heart Contraction
Organ Development
Muscle System Process
Muscle Organ Development
Cellular Calcium Ion Homeostasis
Striated Muscle Contraction
Calcium Ion Homeostasis
Striated Muscle Tissue Development
Negative Regulation Of ATPase Activity
Muscle Tissue Development
Regulation Of Systemic Arterial Blood Pressure
Movement Of Cell Or Subcellular Component
Anatomical Structure Morphogenesis
Cellular Metal Ion Homeostasis
Blood Vessel Morphogenesis
Cellular Cation Homeostasis
Cellular Ion Homeostasis
Metal Ion Homeostasis
System Development
Neurological System Process Involved In Regulation Of Systemic Arterial Blood Pressure
Heart Development
Blood Vessel Development
Cellular Chemical Homeostasis
Regulation Of Blood Pressure
Vasculature Development
Ion Homeostasis
Wound Healing
Multicellular Organismal Development
Anatomical Structure Development
Tagcloud
?
apposition
axin2
bending
bf
bfr
bones
canonical
compromised
csa
determinant
epsilon
histomorphometric
hz
ko
littermate
loaded
loading
mar
mechanical
mineral
nfatc1
periosteal
periosteum
reductions
tibia
unloaded
wnt
wnt16
wt
Tagcloud (Difference)
?
apposition
axin2
bending
bf
bfr
bones
canonical
compromised
csa
determinant
epsilon
histomorphometric
hz
ko
littermate
loaded
loading
mar
mechanical
mineral
nfatc1
periosteal
periosteum
reductions
tibia
unloaded
wnt
wnt16
wt
Tagcloud (Intersection)
?