CLEC3B and GADD45A

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		CLEC3B	GADD45A
Gene Name		C-type lectin domain family 3, member B	growth arrest and DNA-damage-inducible, alpha
Image
Gene Ontology Annotations	Cellular Component	Granular Component Extracellular Region Extracellular Space Cytoplasm Extracellular Matrix Extracellular Vesicular Exosome	Nucleus Cytoplasm
	Molecular Function	Calcium Ion Binding Heparin Binding Carbohydrate Binding Kringle Domain Binding	Core Promoter Binding Protein Binding
	Biological Process	Skeletal System Development Ossification Positive Regulation Of Plasminogen Activation Bone Mineralization Cellular Response To Organic Substance Cellular Response To Transforming Growth Factor Beta Stimulus	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Activation Of MAPKKK Activity DNA Repair Negative Regulation Of Protein Kinase Activity Apoptotic Process Cell Cycle Arrest Centrosome Cycle Signal Transduction In Response To DNA Damage Positive Regulation Of Apoptotic Process Positive Regulation Of JNK Cascade Cellular Response To Mechanical Stimulus Cellular Response To Ionizing Radiation Positive Regulation Of P38MAPK Cascade Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ANXA7 APP CDKN1A GADD45A GSK3B HGF PLAT PLG RPS6KA6 RPS6KB1 SH3GL2 TK1	65 interactors: ADAP1 ASCC2 AURKA BAG6 C14orf1 CCNB1 CDK1 CDK11A CDKN1A CENPB CHD3 CLEC3B DCTN2 DNAJC13 EEF1A1 EEF1G FAM83D FAS FBN3 FTL GADD45GIP1 GAPDH GBP2 GNB2 HIST1H1A HIST1H2AL HIST2H2BE HIST3H3 HIST4H4 IGHM IGSF21 JMJD1C KHSRP LMO4 MAP3K4 MAPK14 MASP1 MDM2 MICAL1 MIDN MPP1 NPM1 NRBP1 NUCB2 PCNA PFKFB4 PPARA PSMC3 PTN PTPRK QARS RAI1 RBPJ RPS2 RXRA SH3GLB1 SPTBN4 SYNE4 TLE1 TP53 UBE2D1 UBR1 VIM ZHX1 ZNF135
Entrez ID		7123	1647
HPRD ID		01759	00528
Ensembl ID		ENSG00000163815	ENSG00000116717
Uniprot IDs		E9PHK0 P05452	A5JUZ3 P24522
PDB IDs		1HTN 1RJH 1TN3	2KG4
Enriched GO Terms of Interacting Partners?		Response To External Stimulus Locomotion Movement Of Cell Or Subcellular Component Response To Stress Response To Abiotic Stimulus Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Glucocorticoid Response To Corticosteroid Negative Regulation Of Cellular Protein Metabolic Process Hemostasis Negative Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Response To Stimulus Apoptotic Process Cell Differentiation Programmed Cell Death Cell Death Response To Organic Substance Platelet Degranulation Death Regulation Of Body Fluid Levels Cellular Response To Growth Factor Stimulus Anatomical Structure Development Chemotaxis Response To Growth Factor Positive Regulation Of Cellular Protein Metabolic Process Cell Development Signal Transduction In Response To DNA Damage Positive Regulation Of Protein Metabolic Process Response To Wounding Regulation Of Cellular Protein Metabolic Process Cell Morphogenesis Involved In Differentiation Developmental Process Regulation Of Protein Kinase Activity Regulation Of Phosphorylation Negative Regulation Of Cellular Metabolic Process Response To Heat Regulation Of Signaling Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Regulation Of Protein Metabolic Process Axon Guidance Negative Regulation Of Phosphorylation Cell Migration Regulation Of Phosphorus Metabolic Process Phosphatidylinositol-mediated Signaling Blood Coagulation Response To Organic Cyclic Compound Cell Motility Epidermal Growth Factor Receptor Signaling Pathway	Regulation Of Metabolic Process Cell Cycle Cell Cycle Process Regulation Of Gene Expression Mitotic Cell Cycle Mitotic Cell Cycle Process Cellular Response To Organic Substance Regulation Of Protein Metabolic Process Organelle Organization DNA Packaging DNA Conformation Change Negative Regulation Of Cellular Metabolic Process Apoptotic Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Chromosome Organization Cell Aging Protein Complex Assembly Chromatin Organization Negative Regulation Of Cell Cycle Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Cell Death Death Positive Regulation Of Protein Metabolic Process Cell Cycle Checkpoint Positive Regulation Of Cellular Protein Catabolic Process Response To Organic Substance DNA Damage Checkpoint Chromatin Assembly Or Disassembly Stress-induced Premature Senescence Immune Response Mitotic Cell Cycle Checkpoint Positive Regulation Of Cellular Protein Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Gene Expression Mitotic DNA Damage Checkpoint Immune System Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Cell Death Positive Regulation Of Metabolic Process Innate Immune Response Mitotic DNA Integrity Checkpoint Response To Toxic Substance Positive Regulation Of Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Regulation Of Mitotic Cell Cycle Positive Regulation Of Proteolysis Cellular Response To Oxygen Levels
Tagcloud ?			2h5 accompanies anova dynactin gtf2h5 invites keuls macaques malfunctioning nbn1 ndd ndds newman ovx perimenopausal presenilin1 proteosome psen1 rad23a raphe scna serotonin speculation subserving symptomology ube2d3 ube3a ubea5 ubiquinase
Tagcloud (Difference) ?			2h5 accompanies anova dynactin gtf2h5 invites keuls macaques malfunctioning nbn1 ndd ndds newman ovx perimenopausal presenilin1 proteosome psen1 rad23a raphe scna serotonin speculation subserving symptomology ube2d3 ube3a ubea5 ubiquinase
Tagcloud (Intersection) ?