CLEC3B and RPS6KA6

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		CLEC3B	RPS6KA6
Gene Name		C-type lectin domain family 3, member B	ribosomal protein S6 kinase, 90kDa, polypeptide 6
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Granular Component Extracellular Region Extracellular Space Cytoplasm Extracellular Matrix Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nucleolus Mitochondrion Cytosol
	Molecular Function	Calcium Ion Binding Heparin Binding Carbohydrate Binding Kringle Domain Binding	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Skeletal System Development Ossification Positive Regulation Of Plasminogen Activation Bone Mineralization Cellular Response To Organic Substance Cellular Response To Transforming Growth Factor Beta Stimulus	Protein Phosphorylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Signal Transduction Synaptic Transmission Axon Guidance Central Nervous System Development Negative Regulation Of Embryonic Development Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Mesoderm Development
Pathways			Axon guidance RSK activation Activation of NMDA receptor upon glutamate binding and postsynaptic events L1CAM interactions Recycling pathway of L1 CREB phosphorylation through the activation of Ras Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Transmission across Chemical Synapses Post NMDA receptor activation events
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ANXA7 APP CDKN1A GADD45A GSK3B HGF PLAT PLG RPS6KA6 RPS6KB1 SH3GL2 TK1	28 interactors: ADIRF APP C14orf1 CEBPZ CENPB CLEC3B DHX34 DNAJC13 DNMT1 FBN3 FZD5 LMO4 MAPK3 MASP1 MED24 MICAL1 MPP1 NR4A1 RBPJ RPLP1 RXRA SAP30BP SPTBN4 SYNE4 UBE2I UFM1 ZNF227 ZNF746
Entrez ID		7123	27330
HPRD ID		01759	02250
Ensembl ID		ENSG00000163815
Uniprot IDs		E9PHK0 P05452	Q9UK32
PDB IDs		1HTN 1RJH 1TN3
Enriched GO Terms of Interacting Partners?		Response To External Stimulus Locomotion Movement Of Cell Or Subcellular Component Response To Stress Response To Abiotic Stimulus Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Glucocorticoid Response To Corticosteroid Negative Regulation Of Cellular Protein Metabolic Process Hemostasis Negative Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Response To Stimulus Apoptotic Process Cell Differentiation Programmed Cell Death Cell Death Response To Organic Substance Platelet Degranulation Death Regulation Of Body Fluid Levels Cellular Response To Growth Factor Stimulus Anatomical Structure Development Chemotaxis Response To Growth Factor Positive Regulation Of Cellular Protein Metabolic Process Cell Development Signal Transduction In Response To DNA Damage Positive Regulation Of Protein Metabolic Process Response To Wounding Regulation Of Cellular Protein Metabolic Process Cell Morphogenesis Involved In Differentiation Developmental Process Regulation Of Protein Kinase Activity Regulation Of Phosphorylation Negative Regulation Of Cellular Metabolic Process Response To Heat Regulation Of Signaling Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Regulation Of Protein Metabolic Process Axon Guidance Negative Regulation Of Phosphorylation Cell Migration Regulation Of Phosphorus Metabolic Process Phosphatidylinositol-mediated Signaling Blood Coagulation Response To Organic Cyclic Compound Cell Motility Epidermal Growth Factor Receptor Signaling Pathway	Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Gene Expression Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Initiation Positive Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Intracellular Receptor Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Protein Processing Regulation Of Early Endosome To Late Endosome Transport Cell Differentiation Biosynthetic Process Cardiac Ventricle Development Negative Regulation Of Cellular Metabolic Process Labyrinthine Layer Blood Vessel Development Sterol Metabolic Process Tissue Development Cardiac Chamber Development Neuron Maturation Regulation Of Cell Fate Commitment Apoptotic Process Cell Maturation Negative Regulation Of Protein Processing Regulation Of Cellular Process Tissue Morphogenesis Programmed Cell Death Placenta Blood Vessel Development
Tagcloud ?			anchorage anticipated attribution azacytidine cdna chemoresponse clines codons deleted demethylation depended duplet encompass exclude exon immunoblots indolocarbazole isoforms nt nucleotides penultimate rsk4 situation sparse splice starvation suppressive triplet uncharacterized
Tagcloud (Difference) ?			anchorage anticipated attribution azacytidine cdna chemoresponse clines codons deleted demethylation depended duplet encompass exclude exon immunoblots indolocarbazole isoforms nt nucleotides penultimate rsk4 situation sparse splice starvation suppressive triplet uncharacterized
Tagcloud (Intersection) ?