DYNLT1 and VDAC1

Number of citations of the paper that reports this interaction (PMID 12009301)
23

Data Source:
HPRD (in vivo, in vitro)

		DYNLT1	VDAC1
Gene Name		dynein, light chain, Tctex-type 1	voltage-dependent anion channel 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Spindle Cytoplasmic Dynein Complex Microtubule	Nucleus Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Plasma Membrane Membrane Mitochondrial Nucleoid Pore Complex Extracellular Vesicular Exosome
	Molecular Function	Motor Activity Protein Binding Identical Protein Binding	Protein Binding Voltage-gated Anion Channel Activity Porin Activity Protein Kinase Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Mitotic Nuclear Division Metabolic Process Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Intracellular Transport Of Viral Protein In Host Cell Regulation Of Rac GTPase Activity Viral Entry Into Host Cell Neuron Projection Morphogenesis Negative Regulation Of Neurogenesis Cell Division Regulation Of Cytoskeleton Organization Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus	Behavioral Fear Response Anion Transport Apoptotic Process Neuron-neuron Synaptic Transmission Learning Viral Process Epithelial Cell Differentiation Regulation Of Anion Transport Transmembrane Transport
Pathways			Mitochondrial protein import
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: APP BAG3 BMPR2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 HSPB9 PVR RAD21 SVIL TROAP TUBA3C TXN VDAC1	20 interactors: ADRB2 BAK1 BAX BCL2L1 BCL2L11 CKMT1A CKMT1B CSNK2B DYNLT1 DYNLT3 GSN HK1 KLHL40 MCL1 PPIF PRKCE RAF1 SUMO4 TOMM20 TUBA4A
Entrez ID		6993	7416
HPRD ID		15987	05137
Ensembl ID		ENSG00000146425	ENSG00000213585
Uniprot IDs		P63172	B3KTS5 P21796
PDB IDs			2JK4 2K4T
Enriched GO Terms of Interacting Partners?		Convergent Extension Involved In Neural Plate Elongation Collateral Sprouting Convergent Extension Involved In Organogenesis Neural Plate Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Neurotransmitter Secretion Convergent Extension Neural Plate Development Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Neurotransmitter Levels Cochlea Morphogenesis Neurotransmitter Transport Cell-cell Signaling Non-canonical Wnt Signaling Pathway Secretion By Cell Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cellular Localization Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Cochlea Development Neuromuscular Junction Development Regulation Of Binding Regulation Of Calcium Ion-dependent Exocytosis Secretion Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Protein Metabolic Process Morphogenesis Of An Epithelial Sheet Regulation Of Phosphorylation Regulation Of Protein Kinase Activity Microtubule-based Process Regulation Of Kinase Activity Regulation Of Lung Blood Pressure Synaptic Growth At Neuromuscular Junction Negative Regulation Of Chondrocyte Proliferation Susceptibility To T Cell Mediated Cytotoxicity Developmental Cell Growth Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component Canonical Wnt Signaling Pathway Regulation Of Cellular Amino Acid Metabolic Process Nervous System Development Inner Ear Morphogenesis Negative Regulation Of Vasoconstriction Collateral Sprouting In Absence Of Injury Regulation Of Embryonic Development Apoptotic Process Signaling Positive Regulation Of Canonical Wnt Signaling Pathway Ear Morphogenesis	Apoptotic Mitochondrial Changes Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Extrinsic Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Mitochondrial Membrane Organization Mitochondrial Transport Positive Regulation Of Release Of Cytochrome C From Mitochondria Thymocyte Apoptotic Process B Cell Apoptotic Process Post-embryonic Organ Morphogenesis Positive Regulation Of Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Mitochondrion Organization Mitochondrion Organization Positive Regulation Of Signal Transduction Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Mitochondrion Organization Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway T Cell Apoptotic Process Apoptotic Signaling Pathway Transport Regulation Of Organelle Organization Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Organelle Organization B Cell Negative Selection Apoptotic Process Involved In Morphogenesis Organelle Organization Apoptotic Process Involved In Development Establishment Of Localization In Cell Intracellular Transport Release Of Cytochrome C From Mitochondria Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Apoptotic Process Involved In Embryonic Digit Morphogenesis Post-embryonic Camera-type Eye Morphogenesis Positive Regulation Of Intracellular Signal Transduction Regulation Of Mitochondrial Membrane Potential Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Signal Transduction B Cell Homeostasis Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Developmental Programmed Cell Death Regulation Of Intracellular Signal Transduction Positive Regulation Of Apoptotic Process
Tagcloud ?		1inq53a 250viqd 52gqvd adapter attempt capsid defective dynein hiv immunodeficiency integrase interaction kd ma motifs mutational p150glued particulate predicts proper q252a replication requirement reverse steps tctex transcriptase uncoating	000xg calreticulin cd81 centrifugation cleared contaminating devoid dulbecco eagle exosomal exosome exosomes fill fl3 hek293 impacted microsomes nanoparticle nta overnight pelleted phenol purity sedimentation speeds syntenin tsg101 ultracentrifugation vesicle
Tagcloud (Difference) ?		1inq53a 250viqd 52gqvd adapter attempt capsid defective dynein hiv immunodeficiency integrase interaction kd ma motifs mutational p150glued particulate predicts proper q252a replication requirement reverse steps tctex transcriptase uncoating	000xg calreticulin cd81 centrifugation cleared contaminating devoid dulbecco eagle exosomal exosome exosomes fill fl3 hek293 impacted microsomes nanoparticle nta overnight pelleted phenol purity sedimentation speeds syntenin tsg101 ultracentrifugation vesicle
Tagcloud (Intersection) ?