DYNLT1 and OLFM3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DYNLT1	OLFM3
Description		dynein light chain Tctex-type 1	olfactomedin 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Golgi Apparatus Spindle Cytoskeleton Cytoplasmic Dynein Complex Microtubule Cytoplasmic Microtubule Dynein Complex Secretory Granule Lumen Host Cell Secretory Vesicle Ficolin-1-rich Granule Lumen	Extracellular Region Extracellular Space Golgi Apparatus AMPA Glutamate Receptor Complex Synapse
	Molecular Function	Protein Binding Identical Protein Binding Dynein Intermediate Chain Binding	Protein Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Microtubule-based Movement Nervous System Development Regulation Of G Protein-coupled Receptor Signaling Pathway Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Intracellular Transport Symbiont Entry Into Host Cell Negative Regulation Of Neurogenesis Cell Division Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus Transport Of Viral Material Towards Nucleus	Signal Transduction Eye Photoreceptor Cell Development
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS			Glomerular filtration rate ( 24351856) Menarche (age at onset) ( 25231870) Metabolite levels ( 23823483) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		48 interacting genes: ACOX2 ACTN1 APP ARID4B BAG3 BMPR2 CCDC68 DDX54 DHX33 DNAJA2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 DYNC1I2 FXR2 HAVCR1 HSPB7 HSPB9 ILF2 KIF2A KLK15 LNX1 NHSL2 NTAQ1 NUP153 NUP62 OLFM3 PELO PITX2 PSMA1 PTGES3L-AARSD1 PTH2R PVR RAD21 RBM14 RRAGA SDCBP SIRPA SVIL TCEANC TROAP TUBA3C TXN UXT VDAC1 XRN2	8 interacting genes: ADAMTSL4 APP DYNLT1 GLRX3 MEOX2 MYOC STUB1 TCF4
Entrez ID		6993	118427
HPRD ID		15987	10460
Ensembl ID		ENSG00000146425	ENSG00000118733
Uniprot IDs		P63172	B3KTG9 Q6IMJ0 Q96PB7
PDB IDs		5JPW 8J07 8PR0 8PR1 8PTK 8RGI
Enriched GO Terms of Interacting Partners?		Aggresome Chemical Synaptic Transmission Frizzled Binding Trans-synaptic Signaling Synaptic Signaling Synapse PTB Domain Binding Convergent Extension Involved In Neural Plate Elongation Microtubule-based Process Outflow Tract Morphogenesis Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cytoplasm Presynapse Regulation Of JNK Cascade Amyloid Fibril Formation Convergent Extension Involved In Organogenesis Regulation Of Spontaneous Synaptic Transmission Spindle Pole Convergent Extension Involved In Gastrulation Aggresome Assembly Spontaneous Neurotransmitter Secretion Synaptic Vesicle Exocytosis Positive Regulation Of Cellular Component Organization Transport Along Microtubule Vesicle-mediated Transport In Synapse Dynein Light Chain Binding Neurotransmitter Transport Positive Regulation Of Neuron Projection Arborization Neurotransmitter Secretion Protein-folding Chaperone Binding Cellular Response To Manganese Ion Regulated Exocytosis Regulation Of Exocytosis Centriolar Subdistal Appendage Inclusion Body Assembly Cytoskeleton-dependent Intracellular Transport Negative Regulation Of Transport Apoptotic Process Hsp70 Protein Binding Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Type 2 Mitophagy Cell-cell Signaling Microtubule-based Transport Programmed Cell Death Cell Death Microtubule Convergent Extension Calcium-dependent Activation Of Synaptic Vesicle Fusion Microtubule Motor Activity Response To Manganese Ion	Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Blood Circulation Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway G Protein-coupled Receptor Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Frizzled Binding Identical Protein Binding ERBB2 Signaling Pathway Skeletal Muscle Hypertrophy Transport Of Viral Material Towards Nucleus Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus Negative Regulation Of Muscle Hypertrophy Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Chaperone-mediated Protein Complex Assembly Negative Regulation Of Cardiac Muscle Hypertrophy Pigment Cell Development ERBB Signaling Pathway Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding Positive Regulation Of JNK Cascade Positive Regulation Of Neuron Differentiation Regulation Of Response To Endoplasmic Reticulum Stress Lipoprotein Particle Positive Regulation Of Protein Import Intracellular Transport Of Viral Protein In Host Cell PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Negative Regulation Of Multicellular Organismal Process Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Beta-catenin-TCF7L2 Complex Negative Regulation Of Vascular Associated Smooth Muscle Contraction Positive Regulation Of Apoptotic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Programmed Cell Death Cellular Response To Norepinephrine Stimulus Regulation Of System Process Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling TFIIB-class Transcription Factor Binding Ubiquitin Conjugating Enzyme Complex
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