DYNLT1 and ILF2

Number of citations of the paper that reports this interaction (PubMedID 30217970)
38

Data Source:
BioGRID (two hybrid)

		DYNLT1	ILF2
Description		dynein light chain Tctex-type 1	interleukin enhancer binding factor 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Golgi Apparatus Spindle Cytoskeleton Cytoplasmic Dynein Complex Microtubule Cytoplasmic Microtubule Dynein Complex Secretory Granule Lumen Host Cell Secretory Vesicle Ficolin-1-rich Granule Lumen	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Specific Granule Lumen Tertiary Granule Lumen Ficolin-1-rich Granule Lumen Ribonucleoprotein Complex
	Molecular Function	Protein Binding Identical Protein Binding Dynein Intermediate Chain Binding	DNA Binding RNA Binding Double-stranded RNA Binding Protein Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Microtubule-based Movement Nervous System Development Regulation Of G Protein-coupled Receptor Signaling Pathway Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Intracellular Transport Symbiont Entry Into Host Cell Negative Regulation Of Neurogenesis Cell Division Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus Transport Of Viral Material Towards Nucleus	Positive Regulation Of DNA-templated Transcription
Pathways		Neutrophil degranulation	Neutrophil degranulation PKR-mediated signaling
Drugs
Diseases
GWAS
Interacting Genes		48 interacting genes: ACOX2 ACTN1 APP ARID4B BAG3 BMPR2 CCDC68 DDX54 DHX33 DNAJA2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 DYNC1I2 FXR2 HAVCR1 HSPB7 HSPB9 ILF2 KIF2A KLK15 LNX1 NHSL2 NTAQ1 NUP153 NUP62 OLFM3 PELO PITX2 PSMA1 PTGES3L-AARSD1 PTH2R PVR RAD21 RBM14 RRAGA SDCBP SIRPA SVIL TCEANC TROAP TUBA3C TXN UXT VDAC1 XRN2	22 interacting genes: CCNDBP1 CEBPA DYNLT1 EEF1G EIF2AK2 EP300 ERG EXOSC8 H19 IL7R INCA1 IQGAP1 KRTAP6-3 MEOX2 OGT PICK1 PRKDC PTEN SGSM2 SREK1 TRIM27 ZMYND12
Entrez ID		6993	3608
HPRD ID		15987	04419
Ensembl ID		ENSG00000146425	ENSG00000143621
Uniprot IDs		P63172	B4DY09 F4ZW62 Q12905 Q53FG3
PDB IDs		5JPW 8J07 8PR0 8PR1 8PTK 8RGI
Enriched GO Terms of Interacting Partners?		Aggresome Chemical Synaptic Transmission Frizzled Binding Trans-synaptic Signaling Synaptic Signaling Synapse PTB Domain Binding Convergent Extension Involved In Neural Plate Elongation Microtubule-based Process Outflow Tract Morphogenesis Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cytoplasm Presynapse Regulation Of JNK Cascade Amyloid Fibril Formation Convergent Extension Involved In Organogenesis Regulation Of Spontaneous Synaptic Transmission Spindle Pole Convergent Extension Involved In Gastrulation Aggresome Assembly Spontaneous Neurotransmitter Secretion Synaptic Vesicle Exocytosis Positive Regulation Of Cellular Component Organization Transport Along Microtubule Vesicle-mediated Transport In Synapse Dynein Light Chain Binding Neurotransmitter Transport Positive Regulation Of Neuron Projection Arborization Neurotransmitter Secretion Protein-folding Chaperone Binding Cellular Response To Manganese Ion Regulated Exocytosis Regulation Of Exocytosis Centriolar Subdistal Appendage Inclusion Body Assembly Cytoskeleton-dependent Intracellular Transport Negative Regulation Of Transport Apoptotic Process Hsp70 Protein Binding Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Type 2 Mitophagy Cell-cell Signaling Microtubule-based Transport Programmed Cell Death Cell Death Microtubule Convergent Extension Calcium-dependent Activation Of Synaptic Vesicle Fusion Microtubule Motor Activity Response To Manganese Ion	STAT Family Protein Binding Regulation Of Phosphorus Metabolic Process Negative Regulation Of Phosphate Metabolic Process Protein Domain Specific Binding Chromatin DNA Binding Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of Hematopoietic Stem Cell Differentiation Positive Regulation Of Biosynthetic Process Leukocyte Differentiation Nucleoplasm Defense Response Positive Regulation Of RNA Biosynthetic Process Response To Nutrient Levels Positive Regulation Of Gene Expression Regulation Of Cell Development Negative Regulation Of Cell Cycle Cell Development Mononuclear Cell Differentiation Positive Regulation Of DNA-templated Transcription RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Identical Protein Binding Positive Regulation Of Transcription By RNA Polymerase II Cytoplasm Protein Modification Process T Cell Lineage Commitment Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Peptidyl-lysine Propionylation Histone Acetyltransferase Complex Protein-DNA Complex Regulation Of Protein Modification Process Swimming Histone Lactyltransferase (CoA-dependent) Activity Positive Regulation Of Lymphocyte Differentiation Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Cellular Response To Nutrient Levels Circadian Rhythm Histone Crotonyltransferase Activity Rhythmic Process Phosphorylation Protein Phosphorylation T Cell Differentiation In Thymus Neuron Projection Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Phosphorylation Negative Regulation Of Protein Metabolic Process Negative Regulation Of Protein Phosphorylation
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