TAF9 and UBA1

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TAF9	UBA1
Gene Name		TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa	ubiquitin-like modifier activating enzyme 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	PCAF Complex Nucleoplasm Transcription Factor TFIID Complex STAGA Complex Transcription Factor TFTC Complex Pre-snoRNP Complex MLL1 Complex	Heterochromatin Nucleus Cytoplasm Mitochondrion Lysosomal Membrane Cytosol Endosome Membrane Desmosome Rough Endoplasmic Reticulum Membrane Extracellular Vesicular Exosome
	Molecular Function	P53 Binding DNA Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Activating Transcription Factor Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity C2H2 Zinc Finger Domain Binding	Ubiquitin Activating Enzyme Activity Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Poly(A) RNA Binding
	Biological Process	Chromatin Organization Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Cellular Response To DNA Damage Stimulus Gene Expression Viral Process Positive Regulation Of Cell Growth Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Process Histone H3 Acetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Stabilization Positive Regulation Of Response To Cytokine Stimulus Response To Interleukin-1 Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator	Cellular Response To DNA Damage Stimulus Protein Ubiquitination Modification-dependent Protein Catabolic Process
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Chromatin organization HIV Infection HATs acetylate histones RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation Chromatin modifying enzymes RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		53 interactors: AHR ALL1 ANK2 APP CEBPB CIITA COIL DRAP1 EEF1A1 ELF3 FBL FBLN1 FEZ1 GALNT6 GTF2B HCFC1 HIST3H3 HNF4A HSF1 KLF6 KMT2A KPNA1 KPNA6 LAMTOR5 MYC NCOA2 NCOR1 NDRG1 NFATC2 NR1D2 NUFIP1 RBM48 RELA RNF138 RPS14 RPS24 RUVBL1 RUVBL2 SF3B3 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF6 TAF6L TAF7 TAF8 TBCA TP53 UBA1	39 interactors: BUB3 CDC34 CDK1 CREB3L1 CREB3L2 ECHS1 GAN GRB2 HGS HSPH1 MGMT PIAS3 SEMA3F SMAD5 TAF9 TMCC2 TSSC4 TTC19 UBC UBE2A UBE2B UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2G1 UBE2G2 UBE2H UBE2J1 UBE2K UBE2L3 UBE2R2 UBE2S UBE2T UBE2W UBTD2
Entrez ID		6880	7317
HPRD ID		15983	02440
Ensembl ID		ENSG00000085231	ENSG00000130985
Uniprot IDs		Q16594	P22314
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process RNA Biosynthetic Process Gene Expression Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression DNA-templated Transcription, Initiation Transcription Initiation From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Viral Process Histone Acetylation Biosynthetic Process Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process DNA-templated Transcription, Elongation Positive Regulation Of Metabolic Process Cellular Metabolic Process Peptidyl-lysine Modification Chromatin Organization Chromatin Modification Histone Modification Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process	Protein K48-linked Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein K11-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Cellular Protein Modification Process Proteolysis Catabolic Process Cellular Protein Metabolic Process Regulation Of Ubiquitin-protein Transferase Activity Protein Metabolic Process Protein K63-linked Ubiquitination Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Protein Monoubiquitination Cellular Response To Stress Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Protein Ubiquitination Cellular Metabolic Process Positive Regulation Of Protein Ubiquitination Regulation Of Protein Catabolic Process Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Cellular Response To DNA Damage Stimulus Response To Organic Substance Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Proteasomal Protein Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Toll-like Receptor 3 Signaling Pathway Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Toll-like Receptor 4 Signaling Pathway Mitotic Cell Cycle Checkpoint Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cell Cycle Process Mitotic Spindle Assembly Checkpoint Negative Regulation Of Chromosome Organization Spindle Assembly Checkpoint
Tagcloud ?		acetyltransferase associates box coactivators contacted crosslinking dimerization gcn5 hat hence homology interacting m2 m3 macromolecular max mbi moderately motifs myc partner spt3 staga sub substitutions tad tert transactivation trrap	aspect bax box caspases consisting counterpart debcl degrading documented drosophila e3 fruitfly homologue iaps identifies involve ligase modifier multimeric proteasome proteolytic regulators scf screen shed slimb stimulates trcp ubiquitin
Tagcloud (Difference) ?		acetyltransferase associates coactivators contacted crosslinking dimerization gcn5 hat hence homology interacting m2 m3 macromolecular max mbi moderately motifs myc partner spt3 staga sub substitutions tad tert transactivation trrap	aspect bax caspases consisting counterpart debcl degrading documented drosophila e3 fruitfly homologue iaps identifies involve ligase modifier multimeric proteasome proteolytic regulators scf screen shed slimb stimulates trcp ubiquitin
Tagcloud (Intersection) ?		box