TAF9 and RPS14

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, pull down)
HPRD (two hybrid)

		TAF9	RPS14
Gene Name		TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa	ribosomal protein S14
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	PCAF Complex Nucleoplasm Transcription Factor TFIID Complex STAGA Complex Transcription Factor TFTC Complex Pre-snoRNP Complex MLL1 Complex	Nucleolus Cytoplasm Mitochondrion Cytosol Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	P53 Binding DNA Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Activating Transcription Factor Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity C2H2 Zinc Finger Domain Binding	RNA Binding Structural Constituent Of Ribosome Poly(A) RNA Binding Translation Regulator Activity MRNA 5'-UTR Binding
	Biological Process	Chromatin Organization Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Cellular Response To DNA Damage Stimulus Gene Expression Viral Process Positive Regulation Of Cell Growth Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Process Histone H3 Acetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Stabilization Positive Regulation Of Response To Cytokine Stimulus Response To Interleukin-1 Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator	Ribosomal Small Subunit Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination Regulation Of Translation SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Erythrocyte Differentiation Maturation Of SSU-rRNA Cellular Protein Metabolic Process
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Chromatin organization HIV Infection HATs acetylate histones RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation Chromatin modifying enzymes RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome	Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-Protein Interactions		53 interactors: AHR ALL1 ANK2 APP CEBPB CIITA COIL DRAP1 EEF1A1 ELF3 FBL FBLN1 FEZ1 GALNT6 GTF2B HCFC1 HIST3H3 HNF4A HSF1 KLF6 KMT2A KPNA1 KPNA6 LAMTOR5 MYC NCOA2 NCOR1 NDRG1 NFATC2 NR1D2 NUFIP1 RBM48 RELA RNF138 RPS14 RPS24 RUVBL1 RUVBL2 SF3B3 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF6 TAF6L TAF7 TAF8 TBCA TP53 UBA1	8 interactors: APP CALM1 PEX6 RBBP6 RLIM SMAD2 TAF9 TMEM33
Entrez ID		6880	6208
HPRD ID		15983	00562
Ensembl ID		ENSG00000085231	ENSG00000164587
Uniprot IDs		Q16594	P62263
PDB IDs			3J3A
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process RNA Biosynthetic Process Gene Expression Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression DNA-templated Transcription, Initiation Transcription Initiation From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Viral Process Histone Acetylation Biosynthetic Process Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process DNA-templated Transcription, Elongation Positive Regulation Of Metabolic Process Cellular Metabolic Process Peptidyl-lysine Modification Chromatin Organization Chromatin Modification Histone Modification Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process	Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Platelet Degranulation Random Inactivation Of X Chromosome Protein Stabilization Growth Secretion By Cell Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Synaptic Growth At Neuromuscular Junction Regulation Of Protein Stability Secretion Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Protein Import Into Peroxisome Matrix, Translocation Collateral Sprouting In Absence Of Injury Zygotic Specification Of Dorsal/ventral Axis Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Transcription Initiation From RNA Polymerase II Promoter Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of High Voltage-gated Calcium Channel Activity Cellular Protein Modification Process Platelet Activation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Mesoderm Development Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Primary MiRNA Processing Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Gene Expression, Epigenetic Regulation Of Nodal Signaling Pathway Axon Choice Point Recognition Common-partner SMAD Protein Phosphorylation DNA-templated Transcription, Initiation Positive Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Protein Metabolic Process Establishment Of Localization In Cell Neuron Remodeling Regulation Of Binding Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Developmental Growth Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of Transcription From RNA Polymerase II Promoter Detection Of Calcium Ion SMAD Protein Complex Assembly Regulation Of Cell Communication By Electrical Coupling Dosage Compensation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Phosphoprotein Phosphatase Activity
Tagcloud ?		acetyltransferase associates box coactivators contacted crosslinking dimerization gcn5 hat hence homology interacting m2 m3 macromolecular max mbi moderately motifs myc partner spt3 staga sub substitutions tad tert transactivation trrap	aquaticus eubacteria identities intergenic l14 l15 l18 l24 l30 l5 l6 maritima mesophile operon operons overlapped rpl14 rpl15 rps17 rps8 s10 s17 spacer spc thermophile thermophilus thermotoga thermus
Tagcloud (Difference) ?		acetyltransferase associates box coactivators contacted crosslinking dimerization gcn5 hat hence homology interacting m2 m3 macromolecular max mbi moderately motifs myc partner spt3 staga sub substitutions tad tert transactivation trrap	aquaticus eubacteria identities intergenic l14 l15 l18 l24 l30 l5 l6 maritima mesophile operon operons overlapped rpl14 rpl15 rps17 rps8 s10 s17 spacer spc thermophile thermophilus thermotoga thermus
Tagcloud (Intersection) ?