HSPA13 and XPOT

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		HSPA13	XPOT
Description		heat shock protein family A (Hsp70) member 13	exportin for tRNA
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Nuclear Matrix
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding ATP Hydrolysis Activity Heat Shock Protein Binding Protein Folding Chaperone ATP-dependent Protein Folding Chaperone	TRNA Binding RNA Binding Protein Binding Small GTPase Binding
	Biological Process	Protein Folding Protein Refolding	TRNA Export From Nucleus Intracellular Protein Transport Nucleocytoplasmic Transport TRNA Re-export From Nucleus
Pathways		Regulation of HSF1-mediated heat shock response	tRNA processing in the nucleus
Drugs		Copper
Diseases
GWAS			Mean corpuscular hemoglobin ( 32888494)
Interacting Genes		43 interacting genes: AHCY APP ARHGAP5 BAG6 CAMLG CAND1 CHMP3 CKAP5 CLU CRYGA CTNNA1 DHX30 DHX35 DNM1 DNM3 FRY GIT1 HSP90B1 HSPH1 KIAA0319L LRBA MVP OGT PCBP1 PLXNB3 POLE4 PPP4R3B PSAP PTGES2 PTK2 RALBP1 RMI1 SGTA SGTB SSR1 ST18 TLN2 UBQLN1 UBQLN2 UBQLN4 UBR4 WDR3 XPOT	13 interacting genes: CEBPA FILNC1 HDLBP HSPA13 KRT75 NUP153 NUP214 POU6F2 RAN RANBP2 RNF10 TRA2A XPO7
Entrez ID		6782	11260
HPRD ID		03061	04418
Ensembl ID		ENSG00000155304	ENSG00000184575
Uniprot IDs		A0A140VK72 P48723	O43592
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of ERAD Pathway Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of ERAD Pathway Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Cellular Component Assembly Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Polyubiquitin Modification-dependent Protein Binding ERAD Pathway TRC Complex Positive Regulation Of Catabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Positive Regulation Of Proteasomal Protein Catabolic Process Protein Targeting Positive Regulation Of Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Targeting To Membrane Low-density Lipoprotein Particle Receptor Binding Chromaffin Granule Localization Within Membrane Perinuclear Region Of Cytoplasm Regulation Of Cellular Response To Stress Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Amyloid Fibril Formation Regulation Of Protein Metabolic Process Cellular Localization Protein Insertion Into ER Membrane Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Protein Targeting To ER Identical Protein Binding Cytosol Establishment Of Protein Localization To Endoplasmic Reticulum Protein Phosphatase Binding Autophagy Cytoplasm Positive Regulation Of Protein Metabolic Process Establishment Of Protein Localization To Membrane Positive Regulation Of Microtubule Nucleation Cytoskeleton Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Manganese Ion Establishment Of Protein Localization Negative Regulation Of Protein Catabolic Process	Nuclear Pore Nuclear Export Nuclear Export Signal Receptor Activity Nuclear Transport Nucleocytoplasmic Transport Regulation Of Nucleocytoplasmic Transport Import Into Nucleus Protein Export From Nucleus Protein Import Into Nucleus RNA Transport Negative Regulation Of RNA Export From Nucleus Protein Localization To Nucleus Nucleobase-containing Compound Transport Nuclear Envelope RNA Export From Nucleus Intracellular Protein Transport Nuclear Inclusion Body Regulation Of Intracellular Transport Nuclear Pore Nuclear Basket Regulation Of RNA Export From Nucleus Establishment Of Protein Localization To Organelle MRNA Transport Structural Constituent Of Nuclear Pore Nuclear Localization Sequence Binding Regulation Of Cellular Localization Nucleus RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Cytoplasmic Side Of Nuclear Pore Protein Transport Negative Regulation Of Intracellular Transport Protein Localization To Organelle Intracellular Transport Response To Vitamin B2 C/EBP Complex RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Cytoplasmic Periphery Of The Nuclear Pore Complex Establishment Of Protein Localization Protein-containing Complex Binding CHOP-C/EBP Complex White Fat Cell Proliferation RNA Import Into Nucleus SUMO Ligase Complex Nuclear Pore Cytoplasmic Filaments Viral Penetration Into Host Nucleus Cholesterol Metabolic Process Sterol Metabolic Process Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?