XPOT and KRT75

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		XPOT	KRT75
Description		exportin for tRNA	keratin 75
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Nuclear Matrix	Cornified Envelope Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	TRNA Binding RNA Binding Protein Binding Small GTPase Binding	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	TRNA Export From Nucleus Intracellular Protein Transport Nucleocytoplasmic Transport TRNA Re-export From Nucleus	Hematopoietic Progenitor Cell Differentiation Keratinization Intermediate Filament Organization
Pathways		tRNA processing in the nucleus	Keratinization Formation of the cornified envelope
Drugs
Diseases			Pseudofolliculitis barbae
GWAS		Mean corpuscular hemoglobin ( 32888494)
Interacting Genes		13 interacting genes: CEBPA FILNC1 HDLBP HSPA13 KRT75 NUP153 NUP214 POU6F2 RAN RANBP2 RNF10 TRA2A XPO7	119 interacting genes: - ABI2 AIRIM AMOT ANKS1A ARMC7 ASB15 BCAS2 BEX2 C19orf25 C1orf216 CAMK2A CARD10 CARD9 CATSPERT CCDC102B CCDC197 CCHCR1 CDC37 CDK18 CDKN2D CEP57 CFAP206 CPNE7 CRACR2A DHX15 DMAP1 DTNBP1 DYDC1 EFHC1 EPM2AIP1 FBXO17 FKBP6 GLYCTK GMCL1 GOLGA2 GOLGA6L9 GPANK1 HGS HNRNPF INCA1 IQUB KANK2 KCTD7 KIF9 KIFC3 KRT13 KRT20 KRT24 KRT25 KRT26 KRT27 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 KRT76 LCA5L LMO1 LMO2 LMO4 LONRF1 MAGOHB MID2 MKRN3 MNS1 MTUS2 MYO15B MYOZ3 NCDN NDC80 NEK6 NFKBID NME7 NUDT21 NUP62 OIP5 OSGIN1 PLEKHG4 PM20D2 POLR1C POLR3C RCOR3 RSPH14 SCNM1 SMARCD1 SPAG5 SPTA1 STX11 SUFU TBC1D1 TCHP TEKT1 TEKT4 TJAP1 TNPO2 TNPO3 TRAF1 TRIM23 TRIM27 TRIM54 TRIML2 TSG101 TSSK3 TXLNA TXLNB U2AF1 USHBP1 WASHC1 WASHC3 WWOX XPOT ZNF76 ZWINT
Entrez ID		11260	9119
HPRD ID		04418	11057
Ensembl ID		ENSG00000184575	ENSG00000170454
Uniprot IDs		O43592	O95678
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear Pore Nuclear Export Nuclear Export Signal Receptor Activity Nuclear Transport Nucleocytoplasmic Transport Regulation Of Nucleocytoplasmic Transport Import Into Nucleus Protein Export From Nucleus Protein Import Into Nucleus RNA Transport Negative Regulation Of RNA Export From Nucleus Protein Localization To Nucleus Nucleobase-containing Compound Transport Nuclear Envelope RNA Export From Nucleus Intracellular Protein Transport Nuclear Inclusion Body Regulation Of Intracellular Transport Nuclear Pore Nuclear Basket Regulation Of RNA Export From Nucleus Establishment Of Protein Localization To Organelle MRNA Transport Structural Constituent Of Nuclear Pore Nuclear Localization Sequence Binding Regulation Of Cellular Localization Nucleus RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Cytoplasmic Side Of Nuclear Pore Protein Transport Negative Regulation Of Intracellular Transport Protein Localization To Organelle Intracellular Transport Response To Vitamin B2 C/EBP Complex RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Cytoplasmic Periphery Of The Nuclear Pore Complex Establishment Of Protein Localization Protein-containing Complex Binding CHOP-C/EBP Complex White Fat Cell Proliferation RNA Import Into Nucleus SUMO Ligase Complex Nuclear Pore Cytoplasmic Filaments Viral Penetration Into Host Nucleus Cholesterol Metabolic Process Sterol Metabolic Process Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Keratin Filament Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Structural Molecule Activity Supramolecular Fiber Organization Cytoskeleton Organization Protein Binding Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Motile Cilium Organelle Organization Axonemal A Tubule Inner Sheath Radial Spoke Microtubule-based Process Sperm Flagellum Axonemal Microtubule Cytoplasm Microtubule-based Movement Flagellated Sperm Motility Sperm Motility Cytosol Cilium-dependent Cell Motility Cilium Movement Cilium Movement Involved In Cell Motility Cilium Identical Protein Binding Microtubule Binding Regulation Of Actin Nucleation Microtubule Regulation Of Organelle Organization Spliceosomal Complex CBM Complex Centrosome Regulation Of Arp2/3 Complex-mediated Actin Nucleation Phosphatidylinositol 3-kinase Inhibitor Activity Polymeric Cytoskeletal Fiber Spindle Organization
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