XPOT and NUP214

Number of citations of the paper that reports this interaction (PMID 12138183)
6

Data Source:
HPRD (in vitro)

		XPOT	NUP214
Gene Name		exportin, tRNA	nucleoporin 214kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Pore Nucleoplasm Cytoplasm	Nucleus Nuclear Pore Nucleoplasm Cytosol Focal Adhesion Intracellular Membrane-bounded Organelle
	Molecular Function	TRNA Binding Ran GTPase Binding	Transporter Activity Nucleocytoplasmic Transporter Activity Protein Binding
	Biological Process	TRNA Export From Nucleus Intracellular Protein Transport	Mitotic Cell Cycle Carbohydrate Metabolic Process MRNA Export From Nucleus Protein Import Into Nucleus Protein Export From Nucleus Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Regulation Of Cell Cycle Transmembrane Transport
Pathways			Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport HuR stabilizes mRNA M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Regulation of mRNA stability by proteins that bind AU-rich elements Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear Pore Complex (NPC) Disassembly Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: HDLBP NUP153 NUP214 RAN RANBP2 XPO7	19 interactors: APC CLEC4G DDX19B IPO5 NFX1 NUP107 NUP88 NUPL2 NXF1 NXF2 NXF3 SMAD2 SMAD3 SMAD4 TNPO1 XPO1 XPO5 XPOT ZFP36
Entrez ID		11260	8021
HPRD ID		04418	00258
Ensembl ID			ENSG00000126883
Uniprot IDs		A8KA19 O43592	P35658
PDB IDs			2OIT 3FHC 3FMO 3FMP
Enriched GO Terms of Interacting Partners?		Nucleocytoplasmic Transport Nuclear Transport MRNA Transport Nuclear Import RNA Transport RNA Localization Mitotic Nuclear Envelope Disassembly Viral Life Cycle Protein Export From Nucleus Nuclear Envelope Disassembly Cytoplasmic Transport Nuclear Envelope Organization Glucose Transport Hexose Transport Viral Transcription Regulation Of Glucose Transport Nuclear Export Protein Import Into Nucleus Nucleus Organization Carbohydrate Transport Viral Process Protein Transport Protein Import Establishment Of Protein Localization Intracellular Transport Protein Localization To Nucleus Mitotic Cell Cycle Process Pathogenesis Mitotic Cell Cycle Intracellular Transport Of Virus Protein Localization Establishment Of Localization In Cell Intracellular Protein Transport Cell Cycle Process Small Molecule Metabolic Process Establishment Of Protein Localization To Organelle Cellular Localization Transport Protein Targeting Endomembrane System Organization Cytokine-mediated Signaling Pathway Cellular Protein Localization Cell Cycle Protein Localization To Organelle Cellular Response To Cytokine Stimulus Negative Regulation Of RNA Export From Nucleus Viral Penetration Into Host Nucleus Response To Cytokine Ribosomal Small Subunit Export From Nucleus Membrane Organization	Nucleocytoplasmic Transport Nuclear Transport Nuclear Export RNA Transport RNA Localization MRNA Transport Cytoplasmic Transport RNA Export From Nucleus Viral Process Gene Expression MRNA Export From Nucleus Establishment Of Localization In Cell Intracellular Transport Cellular Localization Protein Transport SMAD Protein Complex Assembly Establishment Of Protein Localization Gene Silencing By RNA Protein Localization Transport Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Gene Silencing Positive Regulation Of Epithelial To Mesenchymal Transition Protein Export From Nucleus Gene Silencing By MiRNA Mitotic Nuclear Envelope Disassembly Transforming Growth Factor Beta Receptor Signaling Pathway Posttranscriptional Gene Silencing Nuclear Envelope Disassembly Positive Regulation Of Stem Cell Differentiation SMAD Protein Signal Transduction Regulation Of Epithelial To Mesenchymal Transition Primary MiRNA Processing Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Cellular Response To Growth Factor Stimulus Viral Life Cycle Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Transcription From RNA Polymerase II Promoter Nuclear Envelope Organization Somatic Stem Cell Maintenance Regulation Of Transforming Growth Factor Beta2 Production Paraxial Mesoderm Morphogenesis Poly(A)+ MRNA Export From Nucleus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Glucose Transport Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Endoderm Development Hexose Transport Embryonic Pattern Specification
Tagcloud ?		12q14 autosomal chromosome duplicated duplication duplications ganglion ggo glaucoma glc1p gns inherited karyotype mapped muller neighboring ntg ocular organized pedigree proximity rassf3 retina retinal tandemly tbk1 tension trait uniform	acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup153 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Difference) ?		12q14 autosomal chromosome duplicated duplication duplications ganglion ggo glaucoma glc1p gns inherited karyotype mapped muller neighboring ntg ocular organized pedigree proximity rassf3 retina retinal tandemly tbk1 tension trait uniform	acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup153 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Intersection) ?