XPOT and NUP153

Number of citations of the paper that reports this interaction (PMID 12138183)
6

Data Source:
HPRD (in vitro)

		XPOT	NUP153
Gene Name		exportin, tRNA	nucleoporin 153kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Pore Nucleoplasm Cytoplasm	Nuclear Pore Nucleoplasm Nucleolus Cytoplasm Nuclear Membrane Nuclear Periphery Nuclear Inclusion Body Nuclear Pore Nuclear Basket
	Molecular Function	TRNA Binding Ran GTPase Binding	DNA Binding Transporter Activity Nucleocytoplasmic Transporter Activity Protein Binding Zinc Ion Binding Structural Constituent Of Nuclear Pore Identical Protein Binding Protein Anchor
	Biological Process	TRNA Export From Nucleus Intracellular Protein Transport	Mitotic Cell Cycle Carbohydrate Metabolic Process Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Viral Entry Into Host Cell Negative Regulation Of RNA Export From Nucleus MRNA Transport Nuclear Pore Complex Assembly Transmembrane Transport Viral Penetration Into Host Nucleus
Pathways			Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS			Height ( 18391951) Obesity-related traits ( 23251661)
Protein-Protein Interactions		6 interactors: HDLBP NUP153 NUP214 RAN RANBP2 XPO7	24 interactors: APC BRCA1 IPO5 KPNA2 KPNB1 MAPK1 MAPK14 MAPK3 NFX1 NUP62 NUTF2 NXF1 NXF2 RAN SENP2 SMAD2 SMAD3 TNPO1 TPR TRN-GTT2-1 XPO1 XPO5 XPO7 XPOT
Entrez ID		11260	9972
HPRD ID		04418	04899
Ensembl ID			ENSG00000124789
Uniprot IDs		A8KA19 O43592	B4DIK2 F6QR24 P49790 Q4LE47 Q7Z743
PDB IDs			2EBQ 2EBR 2EBV 2GQE
Enriched GO Terms of Interacting Partners?		Nucleocytoplasmic Transport Nuclear Transport MRNA Transport Nuclear Import RNA Transport RNA Localization Mitotic Nuclear Envelope Disassembly Viral Life Cycle Protein Export From Nucleus Nuclear Envelope Disassembly Cytoplasmic Transport Nuclear Envelope Organization Glucose Transport Hexose Transport Viral Transcription Regulation Of Glucose Transport Nuclear Export Protein Import Into Nucleus Nucleus Organization Carbohydrate Transport Viral Process Protein Transport Protein Import Establishment Of Protein Localization Intracellular Transport Protein Localization To Nucleus Mitotic Cell Cycle Process Pathogenesis Mitotic Cell Cycle Intracellular Transport Of Virus Protein Localization Establishment Of Localization In Cell Intracellular Protein Transport Cell Cycle Process Small Molecule Metabolic Process Establishment Of Protein Localization To Organelle Cellular Localization Transport Protein Targeting Endomembrane System Organization Cytokine-mediated Signaling Pathway Cellular Protein Localization Cell Cycle Protein Localization To Organelle Cellular Response To Cytokine Stimulus Negative Regulation Of RNA Export From Nucleus Viral Penetration Into Host Nucleus Response To Cytokine Ribosomal Small Subunit Export From Nucleus Membrane Organization	Nucleocytoplasmic Transport Nuclear Transport Cytoplasmic Transport Viral Process Nuclear Export Protein Transport Establishment Of Protein Localization Intracellular Transport RNA Transport Establishment Of Localization In Cell RNA Localization Protein Localization To Nucleus Intracellular Protein Transport Protein Localization Protein Import Into Nucleus Nuclear Import MRNA Transport Cellular Localization Protein Import Protein Export From Nucleus Transport Cellular Protein Localization Protein Localization To Organelle Establishment Of Protein Localization To Organelle Cellular Response To Organic Substance Protein Targeting Regulation Of Intracellular Transport Cell Cycle NLS-bearing Protein Import Into Nucleus Regulation Of Cytoskeleton Organization Gene Expression RNA Export From Nucleus Response To DsRNA Response To Organic Substance Cellular Response To Cytokine Stimulus MAPK Import Into Nucleus Viral Life Cycle Response To Growth Factor Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Transcription, DNA-templated Intracellular Transport Of Virus Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Nucleocytoplasmic Transport Ribosomal Small Subunit Export From Nucleus Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cellular Localization Response To Epidermal Growth Factor Response To Cytokine Regulation Of Intracellular Protein Transport
Tagcloud ?		12q14 autosomal chromosome duplicated duplication duplications ganglion ggo glaucoma glc1p gns inherited karyotype mapped muller neighboring ntg ocular organized pedigree proximity rassf3 retina retinal tandemly tbk1 tension trait uniform	acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup214 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Difference) ?		12q14 autosomal chromosome duplicated duplication duplications ganglion ggo glaucoma glc1p gns inherited karyotype mapped muller neighboring ntg ocular organized pedigree proximity rassf3 retina retinal tandemly tbk1 tension trait uniform	acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup214 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Intersection) ?