XPOT and NUP153

Number of citations of the paper that reports this interaction (PubMedID 35831314)
73

Data Source:
BioGRID (biochemical)
HPRD (in vitro)

		XPOT	NUP153
Description		exportin for tRNA	nucleoporin 153
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Nuclear Matrix	Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Nucleolus Cytosol Membrane Nuclear Membrane Nuclear Periphery Nuclear Inclusion Body Host Cell Nuclear Pore Nuclear Basket
	Molecular Function	TRNA Binding RNA Binding Protein Binding Small GTPase Binding	DNA Binding Protein Binding Nuclear Localization Sequence Binding Zinc Ion Binding Structural Constituent Of Nuclear Pore Identical Protein Binding Protein-membrane Adaptor Activity Metal Ion Binding Molecular Condensate Scaffold Activity
	Biological Process	TRNA Export From Nucleus Intracellular Protein Transport Nucleocytoplasmic Transport TRNA Re-export From Nucleus	RNA Export From Nucleus Protein Import Into Nucleus Nucleocytoplasmic Transport Protein Transport Symbiont Entry Into Host Cell Negative Regulation Of RNA Export From Nucleus MRNA Transport Nuclear Pore Complex Assembly Viral Penetration Into Host Nucleus Amyloid Fibril Formation
Pathways		tRNA processing in the nucleus	ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494)	Femur bone mineral density x serum urate levels interaction ( 34046847) Height ( 18391951) Obesity-related traits ( 23251661)
Interacting Genes		13 interacting genes: CEBPA FILNC1 HDLBP HSPA13 KRT75 NUP153 NUP214 POU6F2 RAN RANBP2 RNF10 TRA2A XPO7	29 interacting genes: APC BRCA1 CEBPA CLK1 DNMT3A DYNLT1 FILNC1 GRSF1 IPO5 KPNA2 KPNB1 MAPK1 MAPK14 MAPK3 NUP62 NXF1 NXF2 PTGER4 RAN SENP2 SMAD2 SMAD3 TNPO1 TPR TRN-GTT2-7 XPO1 XPO5 XPO7 XPOT
Entrez ID		11260	9972
HPRD ID		04418	04899
Ensembl ID		ENSG00000184575	ENSG00000124789
Uniprot IDs		O43592	P49790
PDB IDs			2EBQ 2EBR 2EBV 2GQE 4U0C 4U0D 5TSV 5TSX 6AYA 8CKY 8CL0 9CNU
Enriched GO Terms of Interacting Partners?		Nuclear Pore Nuclear Export Nuclear Export Signal Receptor Activity Nuclear Transport Nucleocytoplasmic Transport Regulation Of Nucleocytoplasmic Transport Import Into Nucleus Protein Export From Nucleus Protein Import Into Nucleus RNA Transport Negative Regulation Of RNA Export From Nucleus Protein Localization To Nucleus Nucleobase-containing Compound Transport Nuclear Envelope RNA Export From Nucleus Intracellular Protein Transport Nuclear Inclusion Body Regulation Of Intracellular Transport Nuclear Pore Nuclear Basket Regulation Of RNA Export From Nucleus Establishment Of Protein Localization To Organelle MRNA Transport Structural Constituent Of Nuclear Pore Nuclear Localization Sequence Binding Regulation Of Cellular Localization Nucleus RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Cytoplasmic Side Of Nuclear Pore Protein Transport Negative Regulation Of Intracellular Transport Protein Localization To Organelle Intracellular Transport Response To Vitamin B2 C/EBP Complex RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Cytoplasmic Periphery Of The Nuclear Pore Complex Establishment Of Protein Localization Protein-containing Complex Binding CHOP-C/EBP Complex White Fat Cell Proliferation RNA Import Into Nucleus SUMO Ligase Complex Nuclear Pore Cytoplasmic Filaments Viral Penetration Into Host Nucleus Cholesterol Metabolic Process Sterol Metabolic Process Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex	Nuclear Transport Nucleocytoplasmic Transport Nuclear Pore RNA Transport Nuclear Export RNA Export From Nucleus Nucleobase-containing Compound Transport Protein Transport Establishment Of Protein Localization Regulation Of Intracellular Transport Protein Localization To Nucleus Intracellular Protein Transport Protein Import Into Nucleus Nucleoplasm Import Into Nucleus Protein Export From Nucleus Intracellular Transport Nuclear Export Signal Receptor Activity Positive Regulation Of Protein Import Into Nucleus Intracellular Protein Localization Establishment Of Localization In Cell RNA Import Into Nucleus Nuclear Import Signal Receptor Activity Regulation Of Nucleocytoplasmic Transport Nuclear Localization Sequence Binding Regulation Of Protein Import Into Nucleus Positive Regulation Of Nucleocytoplasmic Transport Nuclear Envelope MRNA Transport RNA Binding Cellular Localization Positive Regulation Of Intracellular Transport Regulation Of Intracellular Protein Transport Regulation Of Cellular Localization Nuclear Membrane Positive Regulation Of Intracellular Protein Transport Small GTPase Binding Cellular Response To Tumor Necrosis Factor Positive Regulation Of Protein Localization To Nucleus Nucleus Establishment Of Protein Localization To Organelle Phosphatase Binding Response To Tumor Necrosis Factor Regulation Of Ossification MAP Kinase Activity RNA Nuclear Export Complex Pre-miRNA Export From Nucleus Regulation Of Cytoskeleton Organization MRNA Export From Nucleus Cytoplasm
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?