SOD2 and RAB4A

Number of citations of the paper that reports this interaction (PMID 123234)
0

Data Source:
HPRD (in vitro, in vivo)

		SOD2	RAB4A
Gene Name		superoxide dismutase 2, mitochondrial	RAB4A, member RAS oncogene family
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Nucleoid Extracellular Vesicular Exosome	Endosome Membrane Vesicle Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Superoxide Dismutase Activity Oxygen Binding Manganese Ion Binding Identical Protein Binding	GTPase Activity Protein Binding GTP Binding Protein Transporter Activity GDP Binding
	Biological Process	Response To Reactive Oxygen Species Response To Superoxide Age-dependent Response To Reactive Oxygen Species Response To Hypoxia Release Of Cytochrome C From Mitochondria Liver Development Detection Of Oxygen Vasodilation By Acetylcholine Involved In Regulation Of Systemic Arterial Blood Pressure Regulation Of Transcription From RNA Polymerase II Promoter Glutathione Metabolic Process Superoxide Metabolic Process Heart Development Locomotory Behavior Regulation Of Blood Pressure Negative Regulation Of Cell Proliferation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Response To Cold Post-embryonic Development Response To Manganese Ion Response To Zinc Ion Response To Selenium Ion Response To Gamma Radiation Response To Activity Removal Of Superoxide Radicals Respiratory Electron Transport Chain Hemopoiesis Oxygen Homeostasis Response To Lipopolysaccharide Response To L-ascorbic Acid Response To Silicon Dioxide Response To Isolation Stress Response To Immobilization Stress Response To Drug Response To Hydrogen Peroxide Superoxide Anion Generation Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of Fat Cell Differentiation Response To Cadmium Ion Negative Regulation Of Fibroblast Proliferation Neuron Development Response To Axon Injury Erythrophore Differentiation Hydrogen Peroxide Biosynthetic Process Regulation Of Catalytic Activity Protein Homotetramerization Response To Electrical Stimulus Regulation Of Mitochondrial Membrane Potential Iron Ion Homeostasis Response To Hyperoxia Response To Magnetism Cellular Response To Ethanol Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway	Intracellular Protein Transport Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Membrane Organization
Pathways		Detoxification of Reactive Oxygen Species	Translocation of GLUT4 to the plasma membrane
Drugs
Diseases
GWAS		Age-related macular degeneration (GA) ( 22705344)	Aging ( 22773346)
Protein-Protein Interactions		8 interactors: APP CYP4F12 GET4 HDHD2 KIAA1549 NOL12 RAB4A RPS3A	31 interactors: ACTB APBB3 CD2AP CDK1 CHM DYNC1LI1 DYNLL1 EXOC5 GDI2 GRIPAP1 HACE1 IDH3A KIF3B MAPK3 PIN1 PRKCI PTTG1IP RAB11FIP1 RAB7A RABAC1 RABEP1 RABEP2 RABGAP1 RABGEF1 RBSN RUFY1 SOD2 STX4 TP53 VPS52 ZNF830
Entrez ID		6648	5867
HPRD ID		00938	01541
Ensembl ID		ENSG00000112096	ENSG00000168118
Uniprot IDs		P04179	P20338
PDB IDs		1AP5 1AP6 1EM1 1JA8 1LUV 1LUW 1MSD 1N0J 1N0N 1PL4 1PM9 1QNM 1SZX 1VAR 1XDC 1XIL 1ZSP 1ZTE 1ZUQ 2ADP 2ADQ 2GDS 2P4K 2QKA 2QKC 3C3S 3C3T	1YU9 1Z0K 2BMD 2BME
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Pressure Natriuresis Vitamin K Biosynthetic Process Membrane Organization Leukotriene B4 Catabolic Process Vitamin E Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Cellular Localization Establishment Of Protein Localization To Membrane Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Vitamin K Metabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Long-chain Fatty Acid Catabolic Process Protein Insertion Into ER Membrane Neuron Remodeling Cellular Protein Localization Protein Localization To Membrane	Membrane Organization Protein Transport Establishment Of Protein Localization Protein Localization Vesicle-mediated Transport Cell Cycle Transport Regulation Of Catalytic Activity Regulation Of Cellular Localization Organelle Organization Ras Protein Signal Transduction Positive Regulation Of Catalytic Activity Protein Targeting Endocytosis Mitotic Cell Cycle Process Response To Wounding Membrane Fusion Positive Regulation Of GTPase Activity Mitotic Cell Cycle Regulation Of GTPase Activity Regulation Of Protein Localization Mitotic Nuclear Division Intracellular Transport Regulation Of Cellular Component Organization Cellular Localization Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Intracellular Protein Transport Organelle Fusion Regulation Of Mitotic Cell Cycle Regulation Of Establishment Of Protein Localization Blood Coagulation Cellular Protein Localization Hemostasis Regulation Of Intracellular Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Hydrolase Activity Cell Cycle Process Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Membrane Docking Mitotic DNA Damage Checkpoint Positive Regulation Of Transport Regulation Of Signal Transduction Intracellular Signal Transduction Mitotic DNA Integrity Checkpoint Vascular Endothelial Growth Factor Receptor Signaling Pathway Cellular Component Assembly Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Positive Regulation Of Metabolic Process
Tagcloud ?		arbitrary biogenesis catalase centrally damages dihydroethidium dw femoral hypoperfusion iliac ligatures methoxyisobutylisonitrile mibi mimicking minute mmol muscles myopathic paramagnetic pgc proliferator respiration rounded scintigraphic scintigraphies submitted swiss vmax wider	abnormally accessing anova cascades ckit decoupled dex dexamethasone ery erys erythroblast erythroblasts erythropoiesis escape expansion fdr gata1 gpr56 il3 pdgfrbeta polycythemia polycythemic pv repertoire scf tal1 tgfbeta tightly vera
Tagcloud (Difference) ?		arbitrary biogenesis catalase centrally damages dihydroethidium dw femoral hypoperfusion iliac ligatures methoxyisobutylisonitrile mibi mimicking minute mmol muscles myopathic paramagnetic pgc proliferator respiration rounded scintigraphic scintigraphies submitted swiss vmax wider	abnormally accessing anova cascades ckit decoupled dex dexamethasone ery erys erythroblast erythroblasts erythropoiesis escape expansion fdr gata1 gpr56 il3 pdgfrbeta polycythemia polycythemic pv repertoire scf tal1 tgfbeta tightly vera
Tagcloud (Intersection) ?