SOD2 and NOL12

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SOD2	NOL12
Gene Name		superoxide dismutase 2, mitochondrial	nucleolar protein 12
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Nucleoid Extracellular Vesicular Exosome	Nucleolus
	Molecular Function	DNA Binding Superoxide Dismutase Activity Oxygen Binding Manganese Ion Binding Identical Protein Binding	RRNA Binding Poly(A) RNA Binding
	Biological Process	Response To Reactive Oxygen Species Response To Superoxide Age-dependent Response To Reactive Oxygen Species Response To Hypoxia Release Of Cytochrome C From Mitochondria Liver Development Detection Of Oxygen Vasodilation By Acetylcholine Involved In Regulation Of Systemic Arterial Blood Pressure Regulation Of Transcription From RNA Polymerase II Promoter Glutathione Metabolic Process Superoxide Metabolic Process Heart Development Locomotory Behavior Regulation Of Blood Pressure Negative Regulation Of Cell Proliferation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Response To Cold Post-embryonic Development Response To Manganese Ion Response To Zinc Ion Response To Selenium Ion Response To Gamma Radiation Response To Activity Removal Of Superoxide Radicals Respiratory Electron Transport Chain Hemopoiesis Oxygen Homeostasis Response To Lipopolysaccharide Response To L-ascorbic Acid Response To Silicon Dioxide Response To Isolation Stress Response To Immobilization Stress Response To Drug Response To Hydrogen Peroxide Superoxide Anion Generation Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of Fat Cell Differentiation Response To Cadmium Ion Negative Regulation Of Fibroblast Proliferation Neuron Development Response To Axon Injury Erythrophore Differentiation Hydrogen Peroxide Biosynthetic Process Regulation Of Catalytic Activity Protein Homotetramerization Response To Electrical Stimulus Regulation Of Mitochondrial Membrane Potential Iron Ion Homeostasis Response To Hyperoxia Response To Magnetism Cellular Response To Ethanol Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways		Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Age-related macular degeneration (GA) ( 22705344)
Protein-Protein Interactions		8 interactors: APP CYP4F12 GET4 HDHD2 KIAA1549 NOL12 RAB4A RPS3A	12 interactors: APP CDK4 CEP70 DVL3 KIAA1191 KRTAP10-7 SAP18 SF3B3 SLC25A38 SOD2 SSX2IP TERF1
Entrez ID		6648	79159
HPRD ID		00938	17537
Ensembl ID		ENSG00000112096	ENSG00000100101
Uniprot IDs		P04179	Q9UGY1
PDB IDs		1AP5 1AP6 1EM1 1JA8 1LUV 1LUW 1MSD 1N0J 1N0N 1PL4 1PM9 1QNM 1SZX 1VAR 1XDC 1XIL 1ZSP 1ZTE 1ZUQ 2ADP 2ADQ 2GDS 2P4K 2QKA 2QKC 3C3S 3C3T
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Pressure Natriuresis Vitamin K Biosynthetic Process Membrane Organization Leukotriene B4 Catabolic Process Vitamin E Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Cellular Localization Establishment Of Protein Localization To Membrane Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Vitamin K Metabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Long-chain Fatty Acid Catabolic Process Protein Insertion Into ER Membrane Neuron Remodeling Cellular Protein Localization Protein Localization To Membrane	Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Response To Drug Response To Hyperoxia Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Phase Transition Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Cycle Phase Transition Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Cell Cycle Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Vasodilation By Acetylcholine Involved In Regulation Of Systemic Arterial Blood Pressure Erythrophore Differentiation Age-dependent Response To Reactive Oxygen Species Regulation Of Mitotic Cell Cycle MRNA Processing Regulation Of Fibroblast Proliferation Synaptic Growth At Neuromuscular Junction Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Cellular Component Assembly Regulation Of Cell Cycle Process G2/M Transition Of Mitotic Cell Cycle Organelle Organization Collateral Sprouting In Absence Of Injury Telomeric Loop Formation Age-dependent Telomere Shortening Response To Silicon Dioxide Response To Magnetism MRNA Metabolic Process Microtubule-based Transport Telomere Maintenance Via Telomere Shortening Cytoskeleton-dependent Intracellular Transport RNA Processing Transition Metal Ion Homeostasis Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Detection Of Oxygen Collateral Sprouting Axon Midline Choice Point Recognition Non-canonical Wnt Signaling Pathway Via JNK Cascade Age-dependent Response To Oxidative Stress Positive Regulation Of Cell Death Homeostatic Process Intraciliary Transport Involved In Cilium Morphogenesis Response To Selenium Ion Negative Regulation Of Telomere Maintenance Via Telomerase Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Tagcloud ?		arbitrary biogenesis catalase centrally damages dihydroethidium dw femoral hypoperfusion iliac ligatures methoxyisobutylisonitrile mibi mimicking minute mmol muscles myopathic paramagnetic pgc proliferator respiration rounded scintigraphic scintigraphies submitted swiss vmax wider
Tagcloud (Difference) ?		arbitrary biogenesis catalase centrally damages dihydroethidium dw femoral hypoperfusion iliac ligatures methoxyisobutylisonitrile mibi mimicking minute mmol muscles myopathic paramagnetic pgc proliferator respiration rounded scintigraphic scintigraphies submitted swiss vmax wider
Tagcloud (Intersection) ?