MAS1

Name	MAS1 proto-oncogene, G protein-coupled receptor
Structure	No pdb structure
Interactors	4 interactors: ACE2 AGT ARRB2 SNTA1
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Angiotensin Receptor Activity G Protein-coupled Receptor Activity Angiotensin Type II Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Peptide Binding
	Biological Process	Angiotensin-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Inflammatory Response Phospholipase C-activating Angiotensin-activated Signaling Pathway
Pathways	Peptide ligand-binding receptors
GWAS	Body mass index ( 26426971 ) Body mass index (age>50) ( 26426971 ) Body mass index x sex x age interaction (4df test) ( 26426971 ) Lipoprotein (a) levels ( 26377243 ) Metabolite levels ( 23823483 )
Entrez ID	4142
HPRD ID	01306
Ensembl ID	ENSG00000130368
Uniprot IDs	P04201 W8W3P4
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Regulation Of System Process Regulation Of Gap Junction Assembly Positive Regulation Of Gap Junction Assembly Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Regulation Of Heart Contraction Regulation Of Cardiac Conduction Regulation Of Blood Circulation Regulation Of Muscle System Process Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Sodium Channel Regulator Activity Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Systemic Arterial Blood Pressure System Process Regulation Of Membrane Potential Regulation Of Transport Regulation Of Vasoconstriction Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Sodium Ion Transport Regulation Of Cardiac Muscle Hypertrophy Endocytic Vesicle Membrane Regulation Of MAPK Cascade Positive Regulation Of Cell Junction Assembly Blood Vessel Diameter Maintenance Regulation Of Defense Response Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Intracellular Signal Transduction Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Tube Size Positive Regulation Of Membrane Hyperpolarization Regulation Of Cytokine Production G Protein-coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger Type 2 Angiotensin Receptor Binding Angiotensin Receptor Binding Positive Regulation Of L-proline Import Across Plasma Membrane Angiotensin-mediated Drinking Behavior Peptidyl-dipeptidase Activity Regulation Of Biological Quality Negative Regulation Of MAPK Cascade Regulation Of Blood Pressure Receptor-mediated Endocytosis Positive Regulation Of Angiotensin-activated Signaling Pathway Renin-angiotensin Regulation Of Aldosterone Production Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Regulation Of Renal Output By Angiotensin Positive Regulation Of Synaptic Transmission, Dopaminergic Entry Receptor-mediated Virion Attachment To Host Cell Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Multicellular Organismal Process