GLS and ATXN10

Number of citations of the paper that reports this interaction (PMID 16498633)
5

Data Source:
BioGRID (two hybrid)

		GLS	ATXN10
Gene Name		glutaminase	ataxin 10
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Cytosol	Extracellular Space Cytoplasm Cytosol Plasma Membrane Membrane Dendrite Neuronal Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function	Glutaminase Activity Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Suckling Behavior Regulation Of Respiratory Gaseous Exchange By Neurological System Process Glutamate Biosynthetic Process Glutamine Catabolic Process Synaptic Transmission Neurotransmitter Secretion Cellular Amino Acid Biosynthetic Process Glutamate Secretion Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Protein Homotetramerization	Nervous System Development Neuron Projection Development
Pathways		Neurotransmitter Release Cycle Amino acid synthesis and interconversion (transamination) Glutamate Neurotransmitter Release Cycle Metabolism of amino acids and derivatives Transmission across Chemical Synapses
Drugs		L-Glutamic Acid
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ATXN10 PARD6A SNTA1 TAX1BP3	8 interactors: ABCA1 FN1 GLS GNB1 GNB2 GOLGA1 MRPS16 PPP1R12A
Entrez ID		2744	25814
HPRD ID		00700	04624
Ensembl ID		ENSG00000115419	ENSG00000130638
Uniprot IDs		O94925 Q68D38	Q9UBB4
PDB IDs		3CZD 3UNW 3UO9 3VOY 3VOZ 3VP0 3VP1 3VP2 3VP3 3VP4
Enriched GO Terms of Interacting Partners?		Regulation Of Vasoconstriction By Circulating Norepinephrine Negative Regulation Of Peptidyl-cysteine S-nitrosylation Negative Regulation Of Protein Localization To Cell Surface Cell-cell Junction Maintenance Activation Of Cdc42 GTPase Activity Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Positive Regulation Of Cdc42 GTPase Activity Regulation Of Protein Localization To Cell Surface Ventricular Cardiac Muscle Cell Action Potential Regulation Of Membrane Repolarization Cellular Component Maintenance Regulation Of Cdc42 GTPase Activity Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Cdc42 Protein Signal Transduction Regulation Of Sodium Ion Transmembrane Transport Cardiac Muscle Cell Action Potential Activation Of Rho GTPase Activity Regulation Of Cardiac Muscle Cell Contraction Tight Junction Assembly Neuromuscular Junction Development Activation Of Ras GTPase Activity Regulation Of Vasoconstriction Rho Protein Signal Transduction	Cellular Response To Glucagon Stimulus Response To Glucagon Secretion By Cell Synaptic Transmission Energy Reserve Metabolic Process Secretion Regulation Of Myosin-light-chain-phosphatase Activity Calcium-independent Cell-matrix Adhesion Interleukin-1 Beta Secretion Cellular Response To Acid Chemical Platelet Activation Glutamine Catabolic Process Apolipoprotein A-I-mediated Signaling Pathway Interleukin-1 Secretion Glutamate Biosynthetic Process Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Cholesterol Storage High-density Lipoprotein Particle Assembly Muscle Cell Apoptotic Process Establishment Of Localization In Cell Cell-cell Signaling Intracellular Cholesterol Transport Intracellular Sterol Transport Phospholipid Homeostasis Platelet Dense Granule Organization Integrin Activation Phospholipid Efflux Phagocytosis, Engulfment Energy Derivation By Oxidation Of Organic Compounds Regulation Of Respiratory Gaseous Exchange By Neurological System Process Response To Low-density Lipoprotein Particle Interleukin-1 Beta Production Cellular Response To Prostaglandin E Stimulus Cellular Response To Peptide Hormone Stimulus Small Molecule Metabolic Process G-protein Coupled Acetylcholine Receptor Signaling Pathway Cellular Response To Peptide Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Regulation Of Respiratory System Process Cellular Localization G-protein Coupled Receptor Signaling Pathway Cellular Response To Cholesterol Negative Regulation Of Macrophage Derived Foam Cell Differentiation Reverse Cholesterol Transport Response To Laminar Fluid Shear Stress Membrane Invagination Protein-lipid Complex Assembly Response To Lipoprotein Particle Cellular Response To Sterol Positive Regulation Of Cholesterol Efflux
Tagcloud ?		antigenically aphis bursa bursal conformationally d78 delaware dele delmarva ecorii georgia haeiii heptapeptide hypervariable ibdv miss mississippi pbg98 peninsula serologic southeastern spei stui styi swasasgs taqi univax vac vp2	adca adcas arca ascertained ataxia ataxias attct connections cypriot depended drpla encompass geographical hereby pentanucleotide rarer repeat sca sca1 sca10 sca12 sca17 sca2 sca3 sca6 sca7 sca8 scas triplet
Tagcloud (Difference) ?		antigenically aphis bursa bursal conformationally d78 delaware dele delmarva ecorii georgia haeiii heptapeptide hypervariable ibdv miss mississippi pbg98 peninsula serologic southeastern spei stui styi swasasgs taqi univax vac vp2	adca adcas arca ascertained ataxia ataxias attct connections cypriot depended drpla encompass geographical hereby pentanucleotide rarer repeat sca sca1 sca10 sca12 sca17 sca2 sca3 sca6 sca7 sca8 scas triplet
Tagcloud (Intersection) ?